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VPS4B VPS4B ATAD1 ATAD1 IQCA1 IQCA1 BCS1L BCS1L RFC5 RFC5 VPS4A VPS4A RFC1 RFC1 FIGNL2 FIGNL2 ENSCATP00000004934 ENSCATP00000004934 PSMC3 PSMC3 VCP VCP SPG7 SPG7 LONP2 LONP2 ATAD2 ATAD2 TRIP13 TRIP13 ENSCATP00000011745 ENSCATP00000011745 RFC4 RFC4 RFC2 RFC2 CDC6 CDC6 PSMC6 PSMC6 ENSCATP00000015253 ENSCATP00000015253 LOC105589328 LOC105589328 NAV3 NAV3 ENSCATP00000016334 ENSCATP00000016334 FIGN FIGN ENSCATP00000016481 ENSCATP00000016481 AFG3L2 AFG3L2 ENSCATP00000018270 ENSCATP00000018270 SPATA5L1 SPATA5L1 ENSCATP00000020357 ENSCATP00000020357 PSMC5 PSMC5 PEX1 PEX1 IQCA1L IQCA1L ATAD2B ATAD2B KATNAL1 KATNAL1 SPATA5 SPATA5 ENSCATP00000027317 ENSCATP00000027317 KATNAL2 KATNAL2 CHTF18 CHTF18 ATAD5 ATAD5 CLPB CLPB ENSCATP00000041490 ENSCATP00000041490 ORC1 ORC1 PSMC4 PSMC4 WRNIP1 WRNIP1 ATAD3A ATAD3A NSF NSF ENSCATP00000037470 ENSCATP00000037470 CLPX CLPX YME1L1 YME1L1 LONP1 LONP1 SPAST SPAST NVL NVL PSMC2 PSMC2 ENSCATP00000032409 ENSCATP00000032409 PSMC1 PSMC1 PEX6 PEX6 KATNA1 KATNA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (532 aa)
ATAD1AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
IQCA1IQ motif containing with AAA domain 1. (831 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
RFC5Replication factor C subunit 5. (343 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (501 aa)
RFC1Replication factor C subunit 1. (1113 aa)
FIGNL2Fidgetin like 2. (652 aa)
ENSCATP00000004934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (794 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (825 aa)
ATAD2ATPase family AAA domain containing 2. (1382 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
ENSCATP00000011745AAA domain-containing protein. (410 aa)
RFC4Replication factor C subunit 4. (349 aa)
RFC2Replication factor C subunit 2. (352 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (599 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
ENSCATP00000015253AAA domain-containing protein. (373 aa)
LOC105589328AAA domain-containing protein. (683 aa)
NAV3Neuron navigator 3. (2383 aa)
ENSCATP00000016334Uncharacterized protein. (338 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
ENSCATP00000016481AAA domain-containing protein. (370 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (800 aa)
ENSCATP00000018270AAA domain-containing protein. (497 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (740 aa)
ENSCATP00000020357AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PEX1Peroxisomal biogenesis factor 1. (1283 aa)
IQCA1LIQ motif containing with AAA domain 1 like. (819 aa)
ATAD2BATPase family AAA domain containing 2B. (1458 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
SPATA5Spermatogenesis associated 5. (852 aa)
ENSCATP00000027317AAA domain-containing protein; Belongs to the AAA ATPase family. (343 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
CHTF18Chromosome transmission fidelity factor 18. (1003 aa)
ATAD5ATPase family AAA domain containing 5. (1832 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (704 aa)
ENSCATP00000041490AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
WRNIP1WRN helicase interacting protein 1. (665 aa)
ATAD3AATPase family AAA domain containing 3A. (616 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (744 aa)
ENSCATP00000037470AAA domain-containing protein. (389 aa)
CLPXUncharacterized protein. (633 aa)
YME1L1YME1 like 1 ATPase. (765 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (599 aa)
NVLNuclear VCP like. (858 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
ENSCATP00000032409Uncharacterized protein. (359 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PEX6Peroxisomal biogenesis factor 6. (980 aa)
KATNA1Katanin catalytic subunit A1; Belongs to the AAA ATPase family. (322 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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