(30 nodes) ATPase, AAA-type, conserved site network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (532 aa)
	PEX6	Peroxisomal biogenesis factor 6. (980 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	ATAD1	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	BCS1L	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (501 aa)
	ENSCATP00000004934	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
	NVL	Nuclear VCP like. (858 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (599 aa)
	YME1L1	YME1 like 1 ATPase. (765 aa)
	NSF	N-ethylmaleimide sensitive factor, vesicle fusing ATPase. (744 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
	ENSCATP00000041490	AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa)
	PSMC6	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	FIGN	Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
	AFG3L2	AFG3 like matrix AAA peptidase subunit 2. (800 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1. (740 aa)
	ENSCATP00000020357	AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1283 aa)
	ATAD2B	ATPase family AAA domain containing 2B. (1458 aa)
	PSMC3	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ATAD2	ATPase family AAA domain containing 2. (1382 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
	SPATA5	Spermatogenesis associated 5. (852 aa)
	ENSCATP00000027317	AAA domain-containing protein; Belongs to the AAA ATPase family. (343 aa)
	KATNA1	Katanin catalytic subunit A1; Belongs to the AAA ATPase family. (322 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD2	ENSCATP00000020357	ENSCATP00000010060	ENSCATP00000020357	ATPase family AAA domain containing 2.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2	PSMC3	ENSCATP00000010060	ENSCATP00000006808	ATPase family AAA domain containing 2.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2	PSMC4	ENSCATP00000010060	ENSCATP00000039763	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.475
ATAD2	PSMC6	ENSCATP00000010060	ENSCATP00000013555	ATPase family AAA domain containing 2.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2B	ENSCATP00000020357	ENSCATP00000024157	ENSCATP00000020357	ATPase family AAA domain containing 2B.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2B	PSMC3	ENSCATP00000024157	ENSCATP00000006808	ATPase family AAA domain containing 2B.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2B	PSMC4	ENSCATP00000024157	ENSCATP00000039763	ATPase family AAA domain containing 2B.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.475
ATAD2B	PSMC6	ENSCATP00000024157	ENSCATP00000013555	ATPase family AAA domain containing 2B.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
BCS1L	NSF	ENSCATP00000002803	ENSCATP00000037798	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	N-ethylmaleimide sensitive factor, vesicle fusing ATPase.	0.480
ENSCATP00000004934	ENSCATP00000020357	ENSCATP00000004934	ENSCATP00000020357	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.981
ENSCATP00000004934	ENSCATP00000027317	ENSCATP00000004934	ENSCATP00000027317	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.543
ENSCATP00000004934	ENSCATP00000041490	ENSCATP00000004934	ENSCATP00000041490	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.968
ENSCATP00000004934	KATNA1	ENSCATP00000004934	ENSCATP00000028202	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	Katanin catalytic subunit A1; Belongs to the AAA ATPase family.	0.467
ENSCATP00000004934	PSMC1	ENSCATP00000004934	ENSCATP00000030397	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.	0.969
ENSCATP00000004934	PSMC3	ENSCATP00000004934	ENSCATP00000006808	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.981
ENSCATP00000004934	PSMC4	ENSCATP00000004934	ENSCATP00000039763	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.986
ENSCATP00000004934	PSMC5	ENSCATP00000004934	ENSCATP00000020459	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.984
ENSCATP00000004934	PSMC6	ENSCATP00000004934	ENSCATP00000013555	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.964
ENSCATP00000004934	SPATA5	ENSCATP00000004934	ENSCATP00000025891	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	Spermatogenesis associated 5.	0.563
ENSCATP00000004934	SPATA5L1	ENSCATP00000004934	ENSCATP00000019978	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	Spermatogenesis associated 5 like 1.	0.574