(30 nodes) AAA ATPase, AAA+ lid domain network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCATP00000027317	AAA domain-containing protein; Belongs to the AAA ATPase family. (343 aa)
	ENSCATP00000016481	AAA domain-containing protein. (370 aa)
	ENSCATP00000016334	Uncharacterized protein. (338 aa)
	LOC105589328	AAA domain-containing protein. (683 aa)
	ENSCATP00000015253	AAA domain-containing protein. (373 aa)
	PSMC6	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1. (740 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1283 aa)
	ATAD2B	ATPase family AAA domain containing 2B. (1458 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
	SPATA5	Spermatogenesis associated 5. (852 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (532 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	ENSCATP00000032409	Uncharacterized protein. (359 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
	NVL	Nuclear VCP like. (858 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (599 aa)
	YME1L1	YME1 like 1 ATPase. (765 aa)
	NSF	N-ethylmaleimide sensitive factor, vesicle fusing ATPase. (744 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
	ENSCATP00000011745	AAA domain-containing protein. (410 aa)
	ATAD2	ATPase family AAA domain containing 2. (1382 aa)
	AFG3L2	AFG3 like matrix AAA peptidase subunit 2. (800 aa)
	SPG7	SPG7 matrix AAA peptidase subunit, paraplegin. (794 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	PSMC3	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (501 aa)
	ATAD1	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFG3L2	LOC105589328	ENSCATP00000017959	ENSCATP00000016167	AFG3 like matrix AAA peptidase subunit 2.	AAA domain-containing protein.	0.910
AFG3L2	SPG7	ENSCATP00000017959	ENSCATP00000009429	AFG3 like matrix AAA peptidase subunit 2.	SPG7 matrix AAA peptidase subunit, paraplegin.	0.834
ATAD2	ENSCATP00000011745	ENSCATP00000010060	ENSCATP00000011745	ATPase family AAA domain containing 2.	AAA domain-containing protein.	0.475
ATAD2	ENSCATP00000015253	ENSCATP00000010060	ENSCATP00000015253	ATPase family AAA domain containing 2.	AAA domain-containing protein.	0.475
ATAD2	ENSCATP00000016334	ENSCATP00000010060	ENSCATP00000016334	ATPase family AAA domain containing 2.	Uncharacterized protein.	0.475
ATAD2	PSMC3	ENSCATP00000010060	ENSCATP00000006808	ATPase family AAA domain containing 2.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2	PSMC4	ENSCATP00000010060	ENSCATP00000039763	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.475
ATAD2	PSMC6	ENSCATP00000010060	ENSCATP00000013555	ATPase family AAA domain containing 2.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2B	ENSCATP00000011745	ENSCATP00000024157	ENSCATP00000011745	ATPase family AAA domain containing 2B.	AAA domain-containing protein.	0.475
ATAD2B	ENSCATP00000015253	ENSCATP00000024157	ENSCATP00000015253	ATPase family AAA domain containing 2B.	AAA domain-containing protein.	0.475
ATAD2B	ENSCATP00000016334	ENSCATP00000024157	ENSCATP00000016334	ATPase family AAA domain containing 2B.	Uncharacterized protein.	0.475
ATAD2B	PSMC3	ENSCATP00000024157	ENSCATP00000006808	ATPase family AAA domain containing 2B.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ATAD2B	PSMC4	ENSCATP00000024157	ENSCATP00000039763	ATPase family AAA domain containing 2B.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.475
ATAD2B	PSMC6	ENSCATP00000024157	ENSCATP00000013555	ATPase family AAA domain containing 2B.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.475
ENSCATP00000011745	ATAD2	ENSCATP00000011745	ENSCATP00000010060	AAA domain-containing protein.	ATPase family AAA domain containing 2.	0.475
ENSCATP00000011745	ATAD2B	ENSCATP00000011745	ENSCATP00000024157	AAA domain-containing protein.	ATPase family AAA domain containing 2B.	0.475
ENSCATP00000011745	ENSCATP00000015253	ENSCATP00000011745	ENSCATP00000015253	AAA domain-containing protein.	AAA domain-containing protein.	0.945
ENSCATP00000011745	ENSCATP00000016334	ENSCATP00000011745	ENSCATP00000016334	AAA domain-containing protein.	Uncharacterized protein.	0.945
ENSCATP00000011745	ENSCATP00000016481	ENSCATP00000011745	ENSCATP00000016481	AAA domain-containing protein.	AAA domain-containing protein.	0.954
ENSCATP00000011745	KATNAL1	ENSCATP00000011745	ENSCATP00000025029	AAA domain-containing protein.	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...]	0.516