42 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMG1	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2. (288 aa)
	ENSCATP00000012545	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (112 aa)
	CCT5	Chaperonin containing TCP1 subunit 5. (541 aa)
	LOC105596933	Uncharacterized protein. (521 aa)
	CALR3	Calreticulin 3. (284 aa)
	ENSCATP00000016292	Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (245 aa)
	CCT3	T-complex protein 1 subunit gamma. (545 aa)
	CRYAB	Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
	CALR	Calreticulin. (389 aa)
	TBCA	Tubulin-specific chaperone A; Belongs to the TBCA family. (131 aa)
	CLGN	Calmegin. (612 aa)
	CCT6A	Uncharacterized protein. (566 aa)
	ENSCATP00000025852	Uncharacterized protein. (506 aa)
	CCT8	Uncharacterized protein. (548 aa)
	CCT4	T-complex protein 1 subunit delta. (509 aa)
	CCT6B	Chaperonin containing TCP1 subunit 6B. (535 aa)
	GRPEL2	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (225 aa)
	TCP1	Uncharacterized protein. (556 aa)
	GRPEL1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
	CCT7	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (481 aa)
	LOC105584043	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (83 aa)
	ENSCATP00000039428	Uncharacterized protein; Belongs to the GroES chaperonin family. (103 aa)
	CCT2	Chaperonin containing TCP1 subunit 2. (589 aa)
	PFDN4	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
	RSAD1	Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa)
	SDHAF2	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
	TIMM8B	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (98 aa)
	CRYAA	SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (172 aa)
	MDN1	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5597 aa)
	LOC105582850	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (467 aa)
	LOC105581366	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	TIMM13	Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
	ENSCATP00000004528	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (140 aa)
	ENSCATP00000005275	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	TIMM8A	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (97 aa)
	ENSCATP00000007662	Tubulin-specific chaperone A; Belongs to the TBCA family. (108 aa)
	ENSCATP00000007754	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (97 aa)
	HSPE1	Uncharacterized protein; Belongs to the GroES chaperonin family. (108 aa)
	PSMG2	Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
	CANX	Calnexin. (592 aa)
	ENSCATP00000008723	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (53 aa)
	ENSCATP00000009309	Uncharacterized protein; Belongs to the GroES chaperonin family. (91 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALR	CANX	ENSCATP00000019363	ENSCATP00000008317	Calreticulin.	Calnexin.	0.960
CALR	CLGN	ENSCATP00000019363	ENSCATP00000020690	Calreticulin.	Calmegin.	0.910
CALR3	CANX	ENSCATP00000014334	ENSCATP00000008317	Calreticulin 3.	Calnexin.	0.940
CALR3	CLGN	ENSCATP00000014334	ENSCATP00000020690	Calreticulin 3.	Calmegin.	0.910
CANX	CALR	ENSCATP00000008317	ENSCATP00000019363	Calnexin.	Calreticulin.	0.960
CANX	CALR3	ENSCATP00000008317	ENSCATP00000014334	Calnexin.	Calreticulin 3.	0.940
CCT2	CCT3	ENSCATP00000039999	ENSCATP00000018535	Chaperonin containing TCP1 subunit 2.	T-complex protein 1 subunit gamma.	0.999
CCT2	CCT4	ENSCATP00000039999	ENSCATP00000031638	Chaperonin containing TCP1 subunit 2.	T-complex protein 1 subunit delta.	0.999
CCT2	CCT5	ENSCATP00000039999	ENSCATP00000013282	Chaperonin containing TCP1 subunit 2.	Chaperonin containing TCP1 subunit 5.	0.992
CCT2	CCT6A	ENSCATP00000039999	ENSCATP00000023992	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein.	0.995
CCT2	CCT6B	ENSCATP00000039999	ENSCATP00000034094	Chaperonin containing TCP1 subunit 2.	Chaperonin containing TCP1 subunit 6B.	0.991
CCT2	CCT7	ENSCATP00000039999	ENSCATP00000038151	Chaperonin containing TCP1 subunit 2.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.988
CCT2	CCT8	ENSCATP00000039999	ENSCATP00000031533	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein.	0.996
CCT2	ENSCATP00000004528	ENSCATP00000039999	ENSCATP00000004528	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.989
CCT2	ENSCATP00000005275	ENSCATP00000039999	ENSCATP00000005275	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.624
CCT2	ENSCATP00000008723	ENSCATP00000039999	ENSCATP00000008723	Chaperonin containing TCP1 subunit 2.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.988
CCT2	ENSCATP00000009309	ENSCATP00000039999	ENSCATP00000009309	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.624
CCT2	ENSCATP00000012545	ENSCATP00000039999	ENSCATP00000012545	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.984
CCT2	ENSCATP00000025852	ENSCATP00000039999	ENSCATP00000025852	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein.	0.985
CCT2	ENSCATP00000039428	ENSCATP00000039999	ENSCATP00000039428	Chaperonin containing TCP1 subunit 2.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.624