STRINGSTRING
LCK LCK TYK2 TYK2 KIT KIT EPHB1 EPHB1 WEE2 WEE2 CSF1R CSF1R TEC TEC SYK SYK TIE1 TIE1 SRC SRC EPHA6 EPHA6 MST1R MST1R EPHA7 EPHA7 PDGFRA PDGFRA ROS1 ROS1 JAK3 JAK3 INSR INSR ERBB2 ERBB2 JAK2 JAK2 KDR KDR IGF1R IGF1R INSRR INSRR LYN LYN AXL AXL EPHA2 EPHA2 ENSCATP00000012914 ENSCATP00000012914 CSK CSK ITK ITK FES FES NTRK3 NTRK3 EPHA8 EPHA8 ABL1 ABL1 TEK TEK FGFR3 FGFR3 WEE1 WEE1 BTK BTK HCK HCK FLT1 FLT1 MUSK MUSK ABL2 ABL2 MERTK MERTK FYN FYN BLK BLK FLT4 FLT4 EPHA5 EPHA5 EPHA1 EPHA1 EPHA3 EPHA3 RET RET TYRO3 TYRO3 EPHB2 EPHB2 YES1 YES1 SRMS SRMS MATK MATK FGFR2 FGFR2 FGFR4 FGFR4 ZAP70 ZAP70 EPHA4 EPHA4 PTK6 PTK6 EPHB3 EPHB3 FRK FRK EGFR EGFR TXK TXK NTRK2 NTRK2 JAK1 JAK1 FER FER FGFR1 FGFR1 ERBB4 ERBB4 NTRK1 NTRK1 FGR FGR BMX BMX PDGFRB PDGFRB EPHB4 EPHB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LCKTyrosine-protein kinase. (540 aa)
TYK2Tyrosine-protein kinase. (1164 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
EPHB1EPH receptor B1. (984 aa)
WEE2Wee1-like protein kinase. (568 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
TECTyrosine-protein kinase. (630 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
SRCTyrosine-protein kinase. (644 aa)
EPHA6EPH receptor A6. (1130 aa)
MST1RMacrophage stimulating 1 receptor. (1426 aa)
EPHA7EPH receptor A7. (998 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1024 aa)
ROS1Tyrosine-protein kinase receptor. (2345 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
INSRTyrosine-protein kinase receptor. (1339 aa)
ERBB2Receptor protein-tyrosine kinase. (1399 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
INSRRTyrosine-protein kinase receptor. (1296 aa)
LYNTyrosine-protein kinase. (507 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
EPHA2EPH receptor A2. (1033 aa)
ENSCATP00000012914Tyrosine-protein kinase. (399 aa)
CSKTyrosine-protein kinase. (450 aa)
ITKTyrosine-protein kinase. (620 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (856 aa)
NTRK3Tyrosine-protein kinase receptor. (866 aa)
EPHA8EPH receptor A8. (1000 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
WEE1Wee1-like protein kinase. (646 aa)
BTKTyrosine-protein kinase. (659 aa)
HCKTyrosine-protein kinase. (504 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
MUSKMuscle associated receptor tyrosine kinase. (881 aa)
ABL2Tyrosine-protein kinase. (1172 aa)
MERTKMER proto-oncogene, tyrosine kinase. (954 aa)
FYNTyrosine-protein kinase. (537 aa)
BLKTyrosine-protein kinase. (505 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
EPHA5EPH receptor A5. (1038 aa)
EPHA1EPH receptor A1. (976 aa)
EPHA3EPH receptor A3. (984 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
EPHB2EPH receptor B2. (1085 aa)
YES1Tyrosine-protein kinase. (543 aa)
SRMSTyrosine-protein kinase. (492 aa)
MATKTyrosine-protein kinase. (591 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
EPHA4EPH receptor A4. (986 aa)
PTK6Tyrosine-protein kinase. (507 aa)
EPHB3EPH receptor B3. (1008 aa)
FRKTyrosine-protein kinase. (505 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
TXKTyrosine-protein kinase. (527 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
FGRTyrosine-protein kinase. (496 aa)
BMXTyrosine-protein kinase. (679 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
EPHB4EPH receptor B4. (987 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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