STRINGSTRING
FGF16 FGF16 FGF5 FGF5 FGF17 FGF17 KL KL ENSCATP00000044421 ENSCATP00000044421 FLT3LG FLT3LG SPEM1 SPEM1 GRB2 GRB2 FGFR1 FGFR1 FGF7 FGF7 TLR9 TLR9 PIK3C3 PIK3C3 FGF22 FGF22 FGF18 FGF18 AKT2 AKT2 FGF23 FGF23 FGF10 FGF10 FGF19 FGF19 PIK3R4 PIK3R4 PDE3B PDE3B FGFR4 FGFR4 IRS2 IRS2 FGFR2 FGFR2 PIK3R1 PIK3R1 FRS2 FRS2 PIK3CA PIK3CA FGF6 FGF6 TRIB3 TRIB3 PIK3CB PIK3CB PIK3R2 PIK3R2 FGF4 FGF4 GAB2 GAB2 FGFR3 FGFR3 PTPN11 PTPN11 PDPK1 PDPK1 THEM4 THEM4 FGF1 FGF1 FGF8 FGF8 GAB4 GAB4 IRS1 IRS1 FGF9 FGF9 SPEM2 SPEM2 KLB KLB FGF3 FGF3 GAB1 GAB1 ENSCATP00000005869 ENSCATP00000005869 FLT3 FLT3 FGF20 FGF20 FGF2 FGF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
KLKlotho. (1001 aa)
ENSCATP00000044421Uncharacterized protein. (441 aa)
FLT3LGFms related tyrosine kinase 3 ligand. (236 aa)
SPEM1Spermatid maturation 1. (309 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
TLR9TIR domain-containing protein. (1033 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
PDE3BPhosphodiesterase. (1117 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
IRS2Insulin receptor substrate 2. (1338 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
PIK3R2Uncharacterized protein. (624 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
GAB2GRB2 associated binding protein 2. (676 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (552 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (534 aa)
THEM4Thioesterase superfamily member 4. (240 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GAB4GRB2 associated binding protein family member 4. (536 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SPEM2SPEM family member 2. (505 aa)
KLBKlotho beta. (1044 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
ENSCATP00000005869Uncharacterized protein. (526 aa)
FLT3Fms related tyrosine kinase 3. (741 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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