STRINGSTRING
DYNLL2 DYNLL2 ENSCATP00000012820 ENSCATP00000012820 YWHAZ YWHAZ YWHAQ YWHAQ AKT1 AKT1 ENSCATP00000003394 ENSCATP00000003394 ENSCATP00000003364 ENSCATP00000003364 AKT3 AKT3 MAPK8 MAPK8 SFN SFN ENSCATP00000020255 ENSCATP00000020255 ENSCATP00000023795 ENSCATP00000023795 ENSCATP00000037714 ENSCATP00000037714 YWHAB YWHAB PPP3CC PPP3CC E2F1 E2F1 AKT2 AKT2 TFDP1 TFDP1 YWHAE YWHAE YWHAH YWHAH ENSCATP00000040576 ENSCATP00000040576 BCL2L11 BCL2L11 ENSCATP00000042056 ENSCATP00000042056 MAPK10 MAPK10 PPP1R13B PPP1R13B ENSCATP00000042857 ENSCATP00000042857 BCL2 BCL2 DYNLL1 DYNLL1 TP53BP2 TP53BP2 TP53 TP53 YWHAG YWHAG TP73 TP73 BMF BMF PPP3R1 PPP3R1 TP63 TP63 TFDP2 TFDP2 BAD BAD BID BID
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYNLL2Dynein light chain. (89 aa)
ENSCATP0000001282014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSCATP00000003394Transcription factor. (393 aa)
ENSCATP0000000336414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
ENSCATP00000020255Dynein light chain. (83 aa)
ENSCATP0000002379514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (238 aa)
ENSCATP0000003771414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (232 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
PPP3CCSerine/threonine-protein phosphatase. (438 aa)
E2F1E2F transcription factor 1. (437 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
TFDP1Transcription factor. (417 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
ENSCATP0000004057614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
ENSCATP00000042056Dynein light chain. (74 aa)
MAPK10Mitogen-activated protein kinase. (474 aa)
PPP1R13BProtein phosphatase 1 regulatory subunit 13B. (1090 aa)
ENSCATP00000042857Dynein light chain. (79 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
DYNLL1Dynein light chain. (89 aa)
TP53BP2Tumor protein p53 binding protein 2. (1134 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
BMFBcl2 modifying factor. (184 aa)
PPP3R1Uncharacterized protein. (189 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
TFDP2Transcription factor. (446 aa)
BADBCL2 associated agonist of cell death. (167 aa)
BIDBH3 interacting domain death agonist. (244 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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