49 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOB	Ras homolog family member B. (196 aa)
	FCER1G	Fc fragment of IgE receptor Ig. (111 aa)
	SYK	Non-specific protein-tyrosine kinase. (637 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (875 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (512 aa)
	RHOG	Uncharacterized protein. (191 aa)
	ENSCATP00000005869	Uncharacterized protein. (526 aa)
	COL1A1	Collagen type I alpha 1 chain. (1464 aa)
	PRDM2	PR/SET domain 2. (1711 aa)
	ENSCATP00000011395	Uncharacterized protein. (175 aa)
	LYN	Tyrosine-protein kinase. (507 aa)
	ENSCATP00000013162	Uncharacterized protein. (173 aa)
	COL1A2	Collagen type I alpha 2 chain. (1366 aa)
	ENSCATP00000017084	Uncharacterized protein. (185 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (534 aa)
	GP6	Glycoprotein VI platelet. (563 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (856 aa)
	PTPN11	Protein tyrosine phosphatase non-receptor type 11. (552 aa)
	PIK3R6	Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
	CDC42	Uncharacterized protein. (191 aa)
	LAT	Linker for activation of T cells. (270 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PIK3R2	Uncharacterized protein. (624 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
	LCP2	Lymphocyte cytosolic protein 2. (533 aa)
	CLEC1A	C-type lectin domain family 1 member A. (280 aa)
	LOC105571986	Uncharacterized protein. (189 aa)
	ENSCATP00000004469	Uncharacterized protein. (191 aa)
	RHOA	Ras homolog family member A. (193 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (868 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	CLEC1B	C-type lectin domain family 1 member B. (229 aa)
	CLNK	Cytokine dependent hematopoietic cell linker. (428 aa)
	PDPN	Podoplanin. (206 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	MPIG6B	Megakaryocyte and platelet inhibitory receptor G6b. (237 aa)
	SPNS1	Sphingolipid transporter 1 (putative). (571 aa)
	PIK3R5	Phosphoinositide-3-kinase regulatory subunit 5. (880 aa)
	ENSCATP00000042801	Uncharacterized protein. (136 aa)
	LCK	Tyrosine-protein kinase. (540 aa)
	MFSD6	Major facilitator superfamily domain containing 6. (793 aa)
	ENSCATP00000044421	Uncharacterized protein. (441 aa)
	CLEC9A	C-type lectin domain containing 9A. (216 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	FYN	ENSCATP00000021684	ENSCATP00000023367	Uncharacterized protein.	Tyrosine-protein kinase.	0.830
CDC42	PDPK1	ENSCATP00000021684	ENSCATP00000018326	Uncharacterized protein.	3-phosphoinositide dependent protein kinase 1.	0.419
CDC42	PIK3CA	ENSCATP00000021684	ENSCATP00000027089	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.861
CDC42	PIK3CB	ENSCATP00000021684	ENSCATP00000024233	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.947
CDC42	PIK3R1	ENSCATP00000021684	ENSCATP00000027907	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.847
CDC42	PIK3R2	ENSCATP00000021684	ENSCATP00000023918	Uncharacterized protein.	Uncharacterized protein.	0.825
CDC42	PIK3R3	ENSCATP00000021684	ENSCATP00000027270	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 3.	0.809
CDC42	PRKCZ	ENSCATP00000021684	ENSCATP00000025573	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.856
CDC42	RAC2	ENSCATP00000021684	ENSCATP00000034595	Uncharacterized protein.	Rac family small GTPase 2.	0.817
CDC42	RHOA	ENSCATP00000021684	ENSCATP00000005572	Uncharacterized protein.	Ras homolog family member A.	0.845
CDC42	RHOB	ENSCATP00000021684	ENSCATP00000006883	Uncharacterized protein.	Ras homolog family member B.	0.409
CDC42	VAV1	ENSCATP00000021684	ENSCATP00000018444	Uncharacterized protein.	Vav guanine nucleotide exchange factor 1.	0.670
CDC42	VAV2	ENSCATP00000021684	ENSCATP00000025843	Uncharacterized protein.	Vav guanine nucleotide exchange factor 2.	0.871
CDC42	VAV3	ENSCATP00000021684	ENSCATP00000002336	Uncharacterized protein.	Vav guanine nucleotide exchange factor 3.	0.862
CLEC1A	LCP2	ENSCATP00000004287	ENSCATP00000004225	C-type lectin domain family 1 member A.	Lymphocyte cytosolic protein 2.	0.514
CLEC1A	PLCG2	ENSCATP00000004287	ENSCATP00000020331	C-type lectin domain family 1 member A.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.403
CLEC1A	PRDM2	ENSCATP00000004287	ENSCATP00000010021	C-type lectin domain family 1 member A.	PR/SET domain 2.	0.742
CLEC1A	SYK	ENSCATP00000004287	ENSCATP00000002131	C-type lectin domain family 1 member A.	Non-specific protein-tyrosine kinase.	0.714
CLEC1B	CLEC9A	ENSCATP00000032188	ENSCATP00000045564	C-type lectin domain family 1 member B.	C-type lectin domain containing 9A.	0.475
CLEC1B	FCER1G	ENSCATP00000032188	ENSCATP00000000510	C-type lectin domain family 1 member B.	Fc fragment of IgE receptor Ig.	0.404