STRINGSTRING
STK11 STK11 PRKAA2 PRKAA2 PRKAR2A PRKAR2A THAP6 THAP6 AHCYL1 AHCYL1 ENSCATP00000035075 ENSCATP00000035075 GNGT2 GNGT2 PPP2R1A PPP2R1A PPP2R5D PPP2R5D ENSCATP00000033138 ENSCATP00000033138 PPP2CA PPP2CA CNBD2 CNBD2 GCGR GCGR GNB2 GNB2 GNG2 GNG2 GNAS GNAS GNG3 GNG3 GNG8 GNG8 ACACB ACACB GNA11 GNA11 GNG4 GNG4 ITPR2 ITPR2 ITPR3 ITPR3 PLCB2 PLCB2 TKT TKT ENSCATP00000027386 ENSCATP00000027386 CACNB3 CACNB3 ADCY5 ADCY5 AGPAT1 AGPAT1 CACNB2 CACNB2 ENSCATP00000026030 ENSCATP00000026030 FASN FASN LOC105601524 LOC105601524 STX1A STX1A ACACA ACACA VAMP2 VAMP2 CACNA1E CACNA1E SLC2A2 SLC2A2 ACLY ACLY ENSCATP00000023911 ENSCATP00000023911 ADIPOR1 ADIPOR1 TALDO1 TALDO1 SYT5 SYT5 KCNC2 KCNC2 GNGT1 GNGT1 PKLR PKLR ADCY8 ADCY8 SNAP25 SNAP25 ADCY2 ADCY2 RAPGEF4 RAPGEF4 TKTL1 TKTL1 ENSCATP00000018990 ENSCATP00000018990 GNG13 GNG13 CACNA1A CACNA1A SLC2A1 SLC2A1 PLCB3 PLCB3 ABCC8 ABCC8 ADCY6 ADCY6 GCG GCG PRKCA PRKCA PRKAR1A PRKAR1A THAP7 THAP7 MLXIPL MLXIPL ADCY9 ADCY9 RAPGEF3 RAPGEF3 CACNA1D CACNA1D ADIPOR2 ADIPOR2 PPP2R1B PPP2R1B PFKFB1 PFKFB1 GNB3 GNB3 CACNA1F CACNA1F LOC105581531 LOC105581531 KCNJ11 KCNJ11 TKTL2 TKTL2 ADCY7 ADCY7 FAP FAP GNB5 GNB5 MLX MLX MLXIP MLXIP KCNS3 KCNS3 GNG5 GNG5 ENSCATP00000004605 ENSCATP00000004605 CACNA2D2 CACNA2D2 ACSL3 ACSL3 GNG12 GNG12 GNB1 GNB1 FFAR1 FFAR1 PPP2CB PPP2CB MARCKS MARCKS GNB4 GNB4 ENSCATP00000001853 ENSCATP00000001853 CD36 CD36 ADCY3 ADCY3 ADCY4 ADCY4 ENSCATP00000001050 ENSCATP00000001050 ADCY1 ADCY1 GNG11 GNG11 GNA14 GNA14 GNAQ GNAQ ADRA2A ADRA2A PRKAB2 PRKAB2 PRKAR1B PRKAR1B CACNA2D1 CACNA2D1 ACSL4 ACSL4 GLP1R GLP1R PLCB1 PLCB1 KCNG2 KCNG2 GNA15 GNA15 RAP1A RAP1A RAPGEFL1 RAPGEFL1 INS INS PRKACA PRKACA PRKAR2B PRKAR2B CACNA1C CACNA1C STXBP1 STXBP1 GNAI2 GNAI2 IQGAP1 IQGAP1 RAPGEF5 RAPGEF5 PRKAG2 PRKAG2 PRKACB PRKACB ADRA2C ADRA2C ADIPOQ ADIPOQ ENSCATP00000038494 ENSCATP00000038494 ITPR1 ITPR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
THAP6THAP domain containing 6. (222 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
ENSCATP00000035075Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
ENSCATP00000033138Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (585 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (491 aa)
GNB2G protein subunit beta 2. (340 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GNASGNAS complex locus. (1028 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
GNA11G protein subunit alpha 11. (394 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2568 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
TKTTransketolase. (631 aa)
ENSCATP00000027386Uncharacterized protein. (109 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (283 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
ENSCATP00000026030G protein gamma domain-containing protein. (59 aa)
FASNFatty acid synthase. (2511 aa)
LOC105601524Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
ACACAAcetyl-CoA carboxylase alpha. (2389 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2315 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1155 aa)
ENSCATP00000023911Uncharacterized protein. (368 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
SYT5Synaptotagmin 5. (386 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
TKTL1Transketolase like 1. (596 aa)
ENSCATP00000018990Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2497 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (504 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
GCGGlucagon. (180 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PRKAR1AUncharacterized protein. (381 aa)
THAP7THAP domain containing 7. (309 aa)
MLXIPLMLX interacting protein like. (880 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (925 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (479 aa)
GNB3G protein subunit beta 3. (340 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
LOC105581531Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
TKTL2Transketolase like 2. (626 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (770 aa)
GNB5G protein subunit beta 5. (409 aa)
MLXMAX dimerization protein MLX. (298 aa)
MLXIPMLX interacting protein. (919 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSCATP00000004605Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1148 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB1G protein subunit beta 1. (340 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (331 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSCATP00000001853Uncharacterized protein. (293 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ENSCATP00000001050G protein gamma domain-containing protein. (63 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAQUncharacterized protein. (359 aa)
ADRA2AAdrenoceptor alpha 2A. (465 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1069 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (461 aa)
GNA15G protein subunit alpha 15. (374 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (662 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
GNAI2G protein subunit alpha i2. (355 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1696 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADRA2CAdrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family. (336 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
ENSCATP00000038494Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2745 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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