STRINGSTRING
ENSCATP00000043644 ENSCATP00000043644 E2F5 E2F5 LTBP1 LTBP1 UBA52 UBA52 NCOR1 NCOR1 XPO1 XPO1 ENSCATP00000019150 ENSCATP00000019150 ENSCATP00000020093 ENSCATP00000020093 PARD3 PARD3 NEDD8 NEDD8 STUB1 STUB1 CGN CGN PPP1CA PPP1CA IRX4 IRX4 ENSCATP00000014620 ENSCATP00000014620 LTBP3 LTBP3 MAPK1 MAPK1 COL1A2 COL1A2 ITGB3 ITGB3 F11R F11R TGFB2 TGFB2 PPP1R15A PPP1R15A ENSCATP00000011808 ENSCATP00000011808 LDLRAD4 LDLRAD4 PMEPA1 PMEPA1 MAPK3 MAPK3 ENSCATP00000011066 ENSCATP00000011066 TGFBR1 TGFBR1 UBE2M UBE2M MKX MKX TGFB1 TGFB1 CCNT2 CCNT2 PARD3B PARD3B TGFB3 TGFB3 FBN1 FBN1 LOC105595668 LOC105595668 CDK8 CDK8 JUNB JUNB LOC105579396 LOC105579396 SMURF1 SMURF1 LTBP4 LTBP4 LOC105576738 LOC105576738 TGIF2 TGIF2 RHOA RHOA SP1 SP1 STRAP STRAP YBX1 YBX1 PARD6A PARD6A MEN1 MEN1 USP15 USP15 ENSCATP00000003612 ENSCATP00000003612 ENSCATP00000003394 ENSCATP00000003394 CCNQ CCNQ CCNT1 CCNT1 TRIM33 TRIM33 SMAD3 SMAD3 IRX2 IRX2 UBE2D1 UBE2D1 SMAD2 SMAD2 TGIF2LY TGIF2LY ITGB6 ITGB6 ENSCATP00000030060 ENSCATP00000030060 PPM1A PPM1A ENSCATP00000031033 ENSCATP00000031033 ITGB1 ITGB1 WWTR1 WWTR1 ITGA8 ITGA8 CCNK CCNK SKI SKI BAMBI BAMBI TGIF1 TGIF1 CBL CBL PARP1 PARP1 STAT1 STAT1 IRX1 IRX1 RBL1 RBL1 PPP1CC PPP1CC TGFBR2 TGFBR2 ENSCATP00000034747 ENSCATP00000034747 ENSCATP00000034768 ENSCATP00000034768 ENSCATP00000035134 ENSCATP00000035134 SERPINE1 SERPINE1 ZFYVE9 ZFYVE9 ITGB8 ITGB8 NEDD4L NEDD4L SMAD4 SMAD4 ENSCATP00000037022 ENSCATP00000037022 CDK9 CDK9 NCOR2 NCOR2 TFDP1 TFDP1 E2F4 E2F4 ENSCATP00000040163 ENSCATP00000040163 CCNC CCNC RPS27A RPS27A EP300 EP300 HDAC1 HDAC1 ENSCATP00000021984 ENSCATP00000021984 FURIN FURIN SNW1 SNW1 MTMR4 MTMR4 MEIS3 MEIS3 IRX5 IRX5 USP9X USP9X PCSK4 PCSK4 IRX6 IRX6 TFDP2 TFDP2 IRX3 IRX3 LOC105571670 LOC105571670 CDKN2B CDKN2B PRKCZ PRKCZ SKIL SKIL ITGB5 ITGB5 LTBP2 LTBP2 SMURF2 SMURF2 FKBP1A FKBP1A PPP1CB PPP1CB ATP1B4 ATP1B4 SMAD7 SMAD7 ITGAV ITGAV MYC MYC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000043644Ubiquitin-like domain-containing protein. (120 aa)
E2F5E2F transcription factor 5. (346 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1520 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
XPO1Exportin 1. (1070 aa)
ENSCATP00000019150CSD_1 domain-containing protein. (291 aa)
ENSCATP00000020093Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (433 aa)
PARD3Par-3 family cell polarity regulator. (1353 aa)
NEDD8Ubiquitin-like domain-containing protein. (82 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
CGNCingulin. (1203 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
IRX4Iroquois homeobox 4. (515 aa)
ENSCATP00000014620SKIP_SNW domain-containing protein. (480 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
F11RF11 receptor. (259 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (688 aa)
ENSCATP00000011808Ubiquitin-like domain-containing protein. (130 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (259 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (287 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
ENSCATP00000011066Ubiquitin-like domain-containing protein. (74 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
MKXMohawk homeobox. (352 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
PARD3BPar-3 family cell polarity regulator beta. (1204 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FBN1Fibrillin 1. (2871 aa)
LOC105595668Ubiquitin-like domain-containing protein. (126 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1617 aa)
LOC105576738Ubiquitin-like domain-containing protein. (134 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
RHOARas homolog family member A. (193 aa)
SP1Sp1 transcription factor. (786 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
YBX1CSD_1 domain-containing protein. (324 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
MEN1Menin 1. (615 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
ENSCATP00000003612Uncharacterized protein. (380 aa)
ENSCATP00000003394Transcription factor. (393 aa)
CCNQCyclin Q; Belongs to the cyclin family. (248 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
TRIM33Tripartite motif containing 33. (1151 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
IRX2Iroquois homeobox 2. (462 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TGIF2LYTGFB induced factor homeobox 2 like Y-linked. (177 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ENSCATP00000030060Uncharacterized protein. (281 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
CCNKCyclin K; Belongs to the cyclin family. (580 aa)
SKISKI proto-oncogene. (783 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
TGIF1TGFB induced factor homeobox 1. (358 aa)
CBLCbl proto-oncogene. (907 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
STAT1Signal transducer and activator of transcription. (780 aa)
IRX1Iroquois homeobox 1. (480 aa)
RBL1RB transcriptional corepressor like 1. (1108 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ENSCATP00000034747Uncharacterized protein. (1170 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1425 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1257 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ENSCATP00000037022Peptidylprolyl isomerase. (127 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
TFDP1Transcription factor. (417 aa)
E2F4E2F transcription factor 4. (427 aa)
ENSCATP00000040163Uncharacterized protein. (87 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
EP300E1A binding protein p300. (2411 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ENSCATP00000021984PPM-type phosphatase domain-containing protein. (358 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
SNW1SNW domain containing 1. (598 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
MEIS3Meis homeobox 3. (439 aa)
IRX5Iroquois homeobox 5. (483 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2584 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (755 aa)
IRX6Iroquois homeobox 6. (446 aa)
TFDP2Transcription factor. (446 aa)
IRX3Iroquois homeobox 3. (501 aa)
LOC105571670Uncharacterized protein. (235 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
SKILSKI like proto-oncogene. (684 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (621 aa)
FKBP1APeptidylprolyl isomerase. (108 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
SMAD7Mothers against decapentaplegic homolog. (483 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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