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SPNS3 SPNS3 CD3E CD3E LOC105575603 LOC105575603 ENAH ENAH LCP2 LCP2 PGBD4 PGBD4 HLA-DPA1 HLA-DPA1 ENSCATP00000010103 ENSCATP00000010103 HLA-DQB1 HLA-DQB1 NCK1 NCK1 GRAP2 GRAP2 LOC105575604 LOC105575604 ITK ITK ENSCATP00000014761 ENSCATP00000014761 PAK1 PAK1 ENSCATP00000018187 ENSCATP00000018187 LOC105575605 LOC105575605 TRBV27 TRBV27 PLCG2 PLCG2 LOC105576725 LOC105576725 LAT LAT PLCG1 PLCG1 LOC105600307 LOC105600307 LOC105576724 LOC105576724 FYB1 FYB1 EVL EVL PAK3 PAK3 TRAC TRAC ENSCATP00000028696 ENSCATP00000028696 HLA-DPB1 HLA-DPB1 CD4 CD4 ZAP70 ZAP70 PAK2 PAK2 LOC105600305 LOC105600305 CD101 CD101 ENSCATP00000034919 ENSCATP00000034919 LOC105583891 LOC105583891 SPNS1 SPNS1 CD3G CD3G TRBV10-1 TRBV10-1 TRBV11-1 TRBV11-1 VASP VASP TRBV6-1 TRBV6-1 LCK LCK WAS WAS CD247 CD247 CD3D CD3D HLA-DRA HLA-DRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPNS3Sphingolipid transporter 3 (putative). (512 aa)
CD3ECD3e molecule. (198 aa)
LOC105575603Ig-like domain-containing protein. (284 aa)
ENAHENAH actin regulator. (790 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
ENSCATP00000010103Ig-like domain-containing protein. (273 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (284 aa)
NCK1Cytoplasmic protein. (377 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
LOC105575604Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
ITKTyrosine-protein kinase. (620 aa)
ENSCATP00000014761Ig-like domain-containing protein. (262 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ENSCATP00000018187Ig-like domain-containing protein. (265 aa)
LOC105575605Ig-like domain-containing protein. (263 aa)
TRBV27T cell receptor beta variable 27. (148 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
LOC105576725Ig-like domain-containing protein. (283 aa)
LATLinker for activation of T cells. (270 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LOC105600307Ig-like domain-containing protein. (268 aa)
LOC105576724Ig-like domain-containing protein. (283 aa)
FYB1FYN binding protein 1. (839 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
TRACT cell receptor alpha constant. (110 aa)
ENSCATP00000028696Ig-like domain-containing protein. (133 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (462 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
LOC105600305Ig-like domain-containing protein; Belongs to the MHC class II family. (219 aa)
CD101CD101 molecule. (1021 aa)
ENSCATP00000034919Ig-like domain-containing protein. (264 aa)
LOC105583891Ig-like domain-containing protein. (339 aa)
SPNS1Sphingolipid transporter 1 (putative). (571 aa)
CD3GCD3g molecule. (181 aa)
TRBV10-1T cell receptor beta variable 10-1(gene/pseudogene). (131 aa)
TRBV11-1T cell receptor beta variable 11-1. (142 aa)
VASPVasodilator stimulated phosphoprotein. (431 aa)
TRBV6-1T cell receptor beta variable 6-1. (127 aa)
LCKTyrosine-protein kinase. (540 aa)
WASWASP actin nucleation promoting factor. (503 aa)
CD247CD247 molecule. (165 aa)
CD3DCD3d molecule. (171 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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