55 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STUB1	STIP1 homology and U-box containing protein 1. (303 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1298 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	UBE2M	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	ENSCATP00000037022	Peptidylprolyl isomerase. (127 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
	ENSCATP00000043644	Ubiquitin-like domain-containing protein. (120 aa)
	MTMR4	Myotubularin related protein 4. (1195 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (755 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ENSCATP00000011066	Ubiquitin-like domain-containing protein. (74 aa)
	PMEPA1	Prostate transmembrane protein, androgen induced 1. (287 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (259 aa)
	ENSCATP00000011808	Ubiquitin-like domain-containing protein. (130 aa)
	PPP1R15A	Protein phosphatase 1 regulatory subunit 15A. (688 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	ENSCATP00000034768	Ubiquitin-like domain-containing protein. (144 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
	PPP1CC	Serine/threonine-protein phosphatase. (293 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	ENSCATP00000031033	Ubiquitin-like domain-containing protein. (149 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
	SMAD7	Mothers against decapentaplegic homolog. (483 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	FKBP1A	Peptidylprolyl isomerase. (108 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (621 aa)
	LTBP2	Latent transforming growth factor beta binding protein 2. (1821 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (799 aa)
	NEDD8	Ubiquitin-like domain-containing protein. (82 aa)
	XPO1	Exportin 1. (1070 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	LTBP1	Latent transforming growth factor beta binding protein 1. (1520 aa)
	ENSCATP00000035134	Ubiquitin-like domain-containing protein. (146 aa)
	ZFYVE9	Zinc finger FYVE domain-containing protein. (1425 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (769 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (1257 aa)
	CBL	Cbl proto-oncogene. (907 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	USP15	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
	STRAP	Serine/threonine kinase receptor associated protein. (363 aa)
	LOC105576738	Ubiquitin-like domain-containing protein. (134 aa)
	LTBP4	Latent transforming growth factor beta binding protein 4. (1617 aa)
	SMURF1	E3 ubiquitin-protein ligase. (757 aa)
	LOC105579396	Ubiquitin-like domain-containing protein. (156 aa)
	LOC105595668	Ubiquitin-like domain-containing protein. (126 aa)
	FBN1	Fibrillin 1. (2871 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAMBI	SMAD2	ENSCATP00000000550	ENSCATP00000001163	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.508
BAMBI	SMAD3	ENSCATP00000000550	ENSCATP00000002316	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.500
BAMBI	SMAD4	ENSCATP00000000550	ENSCATP00000036741	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.594
BAMBI	SMAD7	ENSCATP00000000550	ENSCATP00000028813	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.906
BAMBI	TGFB1	ENSCATP00000000550	ENSCATP00000009334	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.706
BAMBI	TGFBR1	ENSCATP00000000550	ENSCATP00000010933	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.941
BAMBI	TGFBR2	ENSCATP00000000550	ENSCATP00000034434	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.734
CBL	ENSCATP00000011066	ENSCATP00000000146	ENSCATP00000011066	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.564
CBL	ENSCATP00000011808	ENSCATP00000000146	ENSCATP00000011808	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.516
CBL	ENSCATP00000031033	ENSCATP00000000146	ENSCATP00000031033	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.782
CBL	ENSCATP00000034768	ENSCATP00000000146	ENSCATP00000034768	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.759
CBL	ENSCATP00000035134	ENSCATP00000000146	ENSCATP00000035134	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.782
CBL	ENSCATP00000043644	ENSCATP00000000146	ENSCATP00000043644	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.817
CBL	LOC105576738	ENSCATP00000000146	ENSCATP00000006132	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.626
CBL	LOC105579396	ENSCATP00000000146	ENSCATP00000007127	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.782
CBL	LOC105595668	ENSCATP00000000146	ENSCATP00000007389	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.817
CBL	NEDD4L	ENSCATP00000000146	ENSCATP00000035985	Cbl proto-oncogene.	NEDD4 like E3 ubiquitin protein ligase.	0.793
CBL	NEDD8	ENSCATP00000000146	ENSCATP00000020954	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.564
CBL	RPS27A	ENSCATP00000000146	ENSCATP00000041739	Cbl proto-oncogene.	Ubiquitin-like domain-containing protein.	0.782
CBL	SMURF1	ENSCATP00000000146	ENSCATP00000006607	Cbl proto-oncogene.	E3 ubiquitin-protein ligase.	0.800