Your Input: | |
| | ENSCATP00000038940 | Uncharacterized protein. (566 aa) |
| | TIGD2 | Tigger transposable element derived 2. (525 aa) |
| | RANGAP1 | Ran GTPase activating protein 1. (627 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (927 aa) |
| | ZBTB38 | Zinc finger and BTB domain containing 38. (1195 aa) |
| | TIGD3 | Tigger transposable element derived 3. (471 aa) |
| | ENSCATP00000001118 | WD_REPEATS_REGION domain-containing protein. (357 aa) |
| | LOC105572655 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | SCML1 | Scm polycomb group protein like 1. (359 aa) |
| | ENSCATP00000001543 | Ig-like domain-containing protein. (271 aa) |
| | SMC6 | Structural maintenance of chromosomes 6. (1092 aa) |
| | MAGEF1 | MAGE family member F1. (308 aa) |
| | LOC105572666 | Histone H4. (103 aa) |
| | ENSCATP00000002218 | Uncharacterized protein. (228 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (651 aa) |
| | LOC105572652 | Histone H4. (103 aa) |
| | THRA | Thyroid hormone receptor alpha. (602 aa) |
| | LOC105572651 | Histone H4. (103 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | LOC105572676 | Histone H4. (103 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | LOC105572671 | Histone H4. (103 aa) |
| | LOC105585120 | Histone H4. (103 aa) |
| | CASP8AP2 | Caspase 8 associated protein 2. (1934 aa) |
| | ENSCATP00000003984 | Uncharacterized protein. (276 aa) |
| | LOC105593194 | Histone H4. (103 aa) |
| | LOC105572665 | Histone H4. (103 aa) |
| | ENSCATP00000004545 | Small ubiquitin-related modifier. (101 aa) |
| | MAGEB6B | MAGE family member B6B. (407 aa) |
| | NRIP1 | Nuclear receptor interacting protein 1. (1155 aa) |
| | JRKL | JRK like. (524 aa) |
| | LOC105593174 | Histone H4. (103 aa) |
| | FOXD1 | Forkhead box D1. (468 aa) |
| | SATB2 | DNA-binding protein SATB. (733 aa) |
| | H4C11 | Histone H4. (103 aa) |
| | SP4 | Sp4 transcription factor. (786 aa) |
| | TIGD6 | Tigger transposable element derived 6. (521 aa) |
| | HMGN5 | High mobility group nucleosome binding domain 5. (289 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (266 aa) |
| | SP100 | SP100 nuclear antigen. (863 aa) |
| | CTXN2 | Cortexin 2. (81 aa) |
| | ZBED4 | Zinc finger BED-type containing 4. (1171 aa) |
| | TIGD5 | Tigger transposable element derived 5. (643 aa) |
| | TIGD1 | Tigger transposable element derived 1. (591 aa) |
| | CENPB | Centromere protein B. (605 aa) |
| | TIGD4 | Tigger transposable element derived 4. (512 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | NUP155 | Nucleoporin 155. (1352 aa) |
| | FOXD2 | Forkhead box D2. (486 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1409 aa) |
| | ENSCATP00000008855 | Uncharacterized protein. (331 aa) |
| | CFAP53 | Cilia and flagella associated protein 53. (514 aa) |
| | RING1 | Ring finger protein 1. (412 aa) |
| | NUP58 | Nucleoporin 58. (599 aa) |
| | VDR | Vitamin D receptor. (477 aa) |
| | ENSCATP00000009428 | Rad60-SLD domain-containing protein. (91 aa) |
| | SP3 | Sp3 transcription factor. (780 aa) |
| | ENSCATP00000009666 | Uncharacterized protein. (121 aa) |
| | PGR | Progesterone receptor. (933 aa) |
| | RAE1 | Ribonucleic acid export 1. (368 aa) |
| | STAG2 | Stromal antigen 2. (1268 aa) |
| | TFE3 | Transcription factor binding to IGHM enhancer 3. (575 aa) |
| | ENSCATP00000010735 | Ubiquitin-like domain-containing protein. (132 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1626 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (862 aa) |
| | CETN2 | Centrin 2. (163 aa) |
| | CBX4 | Chromobox 4. (560 aa) |
| | MBD1 | Methyl-CpG binding domain protein 1. (630 aa) |
| | SAFB | Scaffold attachment factor B. (916 aa) |
| | ENSCATP00000011850 | Small ubiquitin-related modifier. (101 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1530 aa) |
| | NUP205 | Nucleoporin 205. (2013 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | NR2C1 | Nuclear receptor subfamily 2 group C member 1. (579 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa) |
| | RECQL4 | RecQ like helicase 4. (1208 aa) |
| | AR | Androgen receptor. (897 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | HNRNPC | RRM domain-containing protein. (278 aa) |
| | SMC5 | SMC_N domain-containing protein. (1201 aa) |
| | NR3C2 | Nuclear receptor subfamily 3 group C member 2. (985 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1632 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | CETN3 | Centrin 3. (191 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | MAGEE1 | MAGE family member E1. (894 aa) |
| | XRCC4 | X-ray repair cross complementing 4. (334 aa) |
| | ENSCATP00000015079 | RRM domain-containing protein. (286 aa) |
| | BMI1 | RING-type domain-containing protein. (326 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (466 aa) |
| | PARK7 | DJ-1_PfpI domain-containing protein. (198 aa) |
| | NUP214 | Nucleoporin 214. (2089 aa) |
| | BIRC5 | Uncharacterized protein. (147 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (325 aa) |
| | RNF2 | Ring finger protein 2. (336 aa) |
| | PHC3 | Polyhomeotic homolog 3. (983 aa) |
| | HIC2 | HIC ZBTB transcriptional repressor 2. (615 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | RANBP2 | RAN binding protein 2. (3196 aa) |
| | NR5A1 | Nuclear receptor subfamily 5 group A member 1. (461 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1979 aa) |
| | TFEB | Transcription factor EB. (490 aa) |
| | NUP35 | Nucleoporin 35. (278 aa) |
| | ENSCATP00000018615 | Uncharacterized protein. (422 aa) |
| | AURKA | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (461 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa) |
| | CENPBD1 | CENPB DNA-binding domain containing 1. (165 aa) |
| | ENSCATP00000019300 | TTD domain-containing protein. (163 aa) |
| | NUP98 | Nucleoporin 98. (1817 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (367 aa) |
| | ENSCATP00000019755 | Rad21_Rec8 domain-containing protein. (141 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (693 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) |
| | TFAP2B | Transcription factor AP-2 beta. (460 aa) |
| | ENSCATP00000020093 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (433 aa) |
| | ENSCATP00000020360 | SP-RING-type domain-containing protein. (201 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | ENSCATP00000020494 | Uncharacterized protein. (408 aa) |
| | RXRA | Retinoid X receptor alpha. (630 aa) |
| | PIAS3 | Protein inhibitor of activated STAT 3. (634 aa) |
| | PIAS2 | Protein inhibitor of activated STAT 2. (619 aa) |
| | ENSCATP00000020728 | Uncharacterized protein. (310 aa) |
| | SP110 | SP110 nuclear body protein. (550 aa) |
| | TOP1MT | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (682 aa) |
| | SP140 | SP140 nuclear body protein. (848 aa) |
| | ZNF350 | Zinc finger protein 350. (533 aa) |
| | TDG | Thymine DNA glycosylase. (410 aa) |
| | ENSCATP00000022567 | Rad60-SLD domain-containing protein. (78 aa) |
| | FAM111B | Family with sequence similarity 111 member B. (731 aa) |
| | NUP88 | Nucleoporin 88. (741 aa) |
| | RAD21 | RAD21 cohesin complex component. (631 aa) |
| | ZNF618 | Zinc finger protein 618. (988 aa) |
| | TRIM28 | Tripartite motif containing 28. (834 aa) |
| | NUP210 | Nucleoporin 210. (1887 aa) |
| | TRIM7 | Tripartite motif containing 7. (511 aa) |
| | PHC1 | Polyhomeotic homolog 1. (1003 aa) |
| | SUMO1 | Ubiquitin-like domain-containing protein. (146 aa) |
| | ENSCATP00000024192 | DJ-1_PfpI domain-containing protein. (150 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (285 aa) |
| | DDX17 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa) |
| | MAGEB4 | MAGE family member B4. (268 aa) |
| | LOC105593170 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa) |
| | ENSCATP00000024775 | Uncharacterized protein. (90 aa) |
| | ENSCATP00000024876 | RRM domain-containing protein. (286 aa) |
| | SP140L | SP140 nuclear body protein like. (571 aa) |
| | STAG1 | Stromal antigen 1. (1291 aa) |
| | E4F1 | E4F transcription factor 1. (785 aa) |
| | KCTD2 | Potassium channel tetramerization domain containing 2. (263 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1515 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | MITF | Melanocyte inducing transcription factor. (519 aa) |
| | NUP50 | Nucleoporin 50. (468 aa) |
| | THRB | Thyroid hormone receptor beta. (476 aa) |
| | ZMIZ2 | Zinc finger MIZ-type containing 2. (920 aa) |
| | MTA1 | Metastasis associated 1. (775 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (561 aa) |
| | RWDD3 | RWD domain containing 3. (267 aa) |
| | SCMH1 | Scm polycomb group protein homolog 1. (660 aa) |
| | XPC | XPC complex subunit, DNA damage recognition and repair factor. (939 aa) |
| | NFATC2IP | Nuclear factor of activated T cells 2 interacting protein. (419 aa) |
| | ENSCATP00000026830 | Uncharacterized protein. (233 aa) |
| | DAXX | Death domain associated protein. (739 aa) |
| | NR1I2 | Nuclear receptor subfamily 1 group I member 2. (473 aa) |
| | HNRNPK | Uncharacterized protein. (466 aa) |
| | VHL | Von Hippel-Lindau tumor suppressor. (213 aa) |
| | CBX5 | Chromobox 5. (191 aa) |
| | RANBP3L | RAN binding protein 3 like. (490 aa) |
| | INCENP | Inner centromere protein. (768 aa) |
| | SENP5 | SUMO specific peptidase 5. (755 aa) |
| | NUP62CL | Nucleoporin 62 C-terminal like. (184 aa) |
| | L3MBTL2 | L3MBTL histone methyl-lysine binding protein 2. (705 aa) |
| | HIC1 | HIC ZBTB transcriptional repressor 1. (733 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (511 aa) |
| | CBX8 | Chromobox 8. (385 aa) |
| | NOP58 | NOP58 ribonucleoprotein. (530 aa) |
| | ENSCATP00000029025 | annotation not available (87 aa) |
| | ENSCATP00000029205 | Rad60-SLD domain-containing protein. (74 aa) |
| | NSMCE4A | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (377 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (237 aa) |
| | NUP210L | Nucleoporin 210 like. (1861 aa) |
| | RWDD2B | RWD domain-containing protein. (319 aa) |
| | ENSCATP00000030652 | Ubiquitin-like domain-containing protein. (136 aa) |
| | CBX2 | Chromobox 2. (530 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (515 aa) |
| | RWDD2A | RWD domain-containing protein. (292 aa) |
| | FAM111A | Family with sequence similarity 111 member A. (611 aa) |
| | ENSCATP00000031206 | Ubiquitin-like domain-containing protein. (128 aa) |
| | CDCA8 | Cell division cycle associated 8. (300 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | POGK | Pogo transposable element derived with KRAB domain. (591 aa) |
| | UBA2 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (667 aa) |
| | ENSCATP00000031513 | Uncharacterized protein. (295 aa) |
| | ENSCATP00000031549 | DJ-1_PfpI domain-containing protein. (131 aa) |
| | NUP160 | Nucleoporin 160. (1436 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | SCML2 | Scm polycomb group protein like 2. (701 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1468 aa) |
| | NUP43 | WD_REPEATS_REGION domain-containing protein. (380 aa) |
| | LOC105573813 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa) |
| | ENSCATP00000032866 | Uncharacterized protein. (66 aa) |
| | ENSCATP00000032940 | ThiF domain-containing protein. (320 aa) |
| | SAFB2 | Scaffold attachment factor B2. (947 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | SUMO2 | Small ubiquitin-related modifier. (95 aa) |
| | NUP42 | Nucleoporin 42. (435 aa) |
| | NUP188 | Nucleoporin 188. (1751 aa) |
| | ENSCATP00000033827 | Uncharacterized protein. (96 aa) |
| | NSMCE2 | SP-RING-type domain-containing protein. (246 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1073 aa) |
| | ENSCATP00000035237 | ROKNT domain-containing protein. (71 aa) |
| | WRN | WRN RecQ like helicase. (1418 aa) |
| | TPR | Translocated promoter region, nuclear basket protein. (2439 aa) |
| | NCOA5 | Nuclear receptor coactivator 5. (579 aa) |
| | LOC105593367 | Uncharacterized protein. (1225 aa) |
| | BLM | BLM RecQ like helicase. (1416 aa) |
| | SATB1 | DNA-binding protein SATB. (794 aa) |
| | ENSCATP00000035593 | Rad60-SLD domain-containing protein. (75 aa) |
| | ENSCATP00000035826 | Uncharacterized protein. (286 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa) |
| | ENSCATP00000035908 | Uncharacterized protein. (247 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (397 aa) |
| | TFAP2A | Transcription factor AP-2 alpha. (391 aa) |
| | NUP54 | Nucleoporin 54. (508 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (550 aa) |
| | ENSCATP00000036401 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (262 aa) |
| | FOXD4L1 | Forkhead box D4 like 1. (408 aa) |
| | ENSCATP00000036518 | BTB domain-containing protein. (145 aa) |
| | LOC105584067 | RING-type domain-containing protein. (334 aa) |
| | ENSCATP00000036747 | Uncharacterized protein. (391 aa) |
| | SAE1 | SUMO1 activating enzyme subunit 1. (335 aa) |
| | HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4801 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | TOPORS | TOP1 binding arginine/serine rich protein. (1085 aa) |
| | NUP153 | Nucleoporin 153. (1515 aa) |
| | SUMO3 | Ubiquitin-like domain-containing protein. (127 aa) |
| | NR3C1 | Nuclear receptor subfamily 3 group C member 1. (778 aa) |
| | LOC105575645 | Nucleoplasmin domain-containing protein. (210 aa) |
| | SP5 | Sp5 transcription factor. (398 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2059 aa) |
| | ZNF131 | Zinc finger protein 131. (611 aa) |
| | RORA | RAR related orphan receptor A. (555 aa) |
| | PCGF2 | Polycomb group ring finger 2. (344 aa) |
| | MAGEB6 | MAGE family member B6. (407 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (482 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2510 aa) |
| | ENSCATP00000039241 | Uncharacterized protein. (287 aa) |
| | ENSCATP00000039328 | Nucleoplasmin domain-containing protein. (209 aa) |
| | SHLD1 | Shieldin complex subunit 1. (254 aa) |
| | NUP37 | Nucleoporin 37. (326 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | NUP133 | Nucleoporin 133. (1156 aa) |
| | LOC105600316 | Uncharacterized protein. (702 aa) |
| | ENSCATP00000040578 | Nucleoplasmin domain-containing protein. (217 aa) |
| | SENP1 | SUMO specific peptidase 1. (627 aa) |
| | RNF169 | Ring finger protein 169. (708 aa) |
| | SENP2 | SUMO specific peptidase 2. (572 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | TFAP2C | Transcription factor AP-2 gamma. (450 aa) |
| | AAAS | Aladin WD repeat nucleoporin. (546 aa) |
| | NUP62 | Nucleoporin 62. (338 aa) |
| | HDAC7 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1017 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa) |
| | SMC3 | Structural maintenance of chromosomes 3. (1007 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | MRTFA | Myocardin related transcription factor A. (970 aa) |
| | UHRF2 | Ubiquitin like with PHD and ring finger domains 2. (802 aa) |
| | RANBP3 | RAN binding protein 3. (567 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa) |
| | ING1 | Inhibitor of growth protein. (397 aa) |
| | RARA | Retinoic acid receptor alpha. (478 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa) |
| | NDC1 | NDC1 transmembrane nucleoporin. (674 aa) |
| | JRK | Jrk helix-turn-helix protein. (558 aa) |
| | SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (739 aa) |
| | NR5A2 | Nuclear receptor subfamily 5 group A member 2. (541 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
