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ENSCATP00000001118 ENSCATP00000001118 SCML1 SCML1 SMC6 SMC6 MAGEF1 MAGEF1 PIAS1 PIAS1 MEIOB MEIOB MAGEB6B MAGEB6B NSMCE1 NSMCE1 SP100 SP100 NUP155 NUP155 RING1 RING1 NUP58 NUP58 ENSCATP00000009428 ENSCATP00000009428 ENSCATP00000009666 ENSCATP00000009666 RAE1 RAE1 STAG2 STAG2 ENSCATP00000010735 ENSCATP00000010735 CETN2 CETN2 CBX4 CBX4 ENSCATP00000011850 ENSCATP00000011850 NUP205 NUP205 RECQL4 RECQL4 SMC5 SMC5 PML PML CETN3 CETN3 MAGEE1 MAGEE1 XRCC4 XRCC4 BMI1 BMI1 NUP214 NUP214 SEC13 SEC13 RNF2 RNF2 PHC3 PHC3 RANBP2 RANBP2 NUP35 NUP35 NUP85 NUP85 NUP98 NUP98 SEH1L SEH1L ENSCATP00000019755 ENSCATP00000019755 ENSCATP00000020360 ENSCATP00000020360 PIAS2 PIAS2 SP110 SP110 SP140 SP140 TDG TDG ENSCATP00000022567 ENSCATP00000022567 NUP88 NUP88 RAD21 RAD21 NUP210 NUP210 PHC1 PHC1 SUMO1 SUMO1 MAGEB4 MAGEB4 ENSCATP00000024775 ENSCATP00000024775 SP140L SP140L STAG1 STAG1 KCTD2 KCTD2 NUP50 NUP50 RNF168 RNF168 SCMH1 SCMH1 XPC XPC NFATC2IP NFATC2IP NUP62CL NUP62CL CBX8 CBX8 ENSCATP00000029025 ENSCATP00000029025 ENSCATP00000029205 ENSCATP00000029205 NSMCE4A NSMCE4A UBE2I UBE2I ENSCATP00000030652 ENSCATP00000030652 CBX2 CBX2 SMC1A SMC1A PIAS4 PIAS4 ENSCATP00000031206 ENSCATP00000031206 NUP160 NUP160 PARP1 PARP1 SCML2 SCML2 NUP43 NUP43 ENSCATP00000032866 ENSCATP00000032866 SUMO2 SUMO2 NUP42 NUP42 NUP188 NUP188 NSMCE2 NSMCE2 WRN WRN TPR TPR LOC105593367 LOC105593367 BLM BLM ENSCATP00000035593 ENSCATP00000035593 NUP107 NUP107 RAD52 RAD52 NUP54 NUP54 ENSCATP00000036401 ENSCATP00000036401 LOC105584067 LOC105584067 HERC2 HERC2 NUP153 NUP153 SUMO3 SUMO3 PCGF2 PCGF2 MAGEB6 MAGEB6 ENSCATP00000038940 ENSCATP00000038940 SHLD1 SHLD1 NUP37 NUP37 NUP133 NUP133 RNF169 RNF169 AAAS AAAS NUP62 NUP62 HDAC7 HDAC7 SMC3 SMC3 BRCA1 BRCA1 NUP93 NUP93 NDC1 NDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000001118WD_REPEATS_REGION domain-containing protein. (357 aa)
SCML1Scm polycomb group protein like 1. (359 aa)
SMC6Structural maintenance of chromosomes 6. (1092 aa)
MAGEF1MAGE family member F1. (308 aa)
PIAS1Protein inhibitor of activated STAT 1. (651 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
MAGEB6BMAGE family member B6B. (407 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (266 aa)
SP100SP100 nuclear antigen. (863 aa)
NUP155Nucleoporin 155. (1352 aa)
RING1Ring finger protein 1. (412 aa)
NUP58Nucleoporin 58. (599 aa)
ENSCATP00000009428Rad60-SLD domain-containing protein. (91 aa)
ENSCATP00000009666Uncharacterized protein. (121 aa)
RAE1Ribonucleic acid export 1. (368 aa)
STAG2Stromal antigen 2. (1268 aa)
ENSCATP00000010735Ubiquitin-like domain-containing protein. (132 aa)
CETN2Centrin 2. (163 aa)
CBX4Chromobox 4. (560 aa)
ENSCATP00000011850Small ubiquitin-related modifier. (101 aa)
NUP205Nucleoporin 205. (2013 aa)
RECQL4RecQ like helicase 4. (1208 aa)
SMC5SMC_N domain-containing protein. (1201 aa)
PMLPromyelocytic leukemia. (882 aa)
CETN3Centrin 3. (191 aa)
MAGEE1MAGE family member E1. (894 aa)
XRCC4X-ray repair cross complementing 4. (334 aa)
BMI1RING-type domain-containing protein. (326 aa)
NUP214Nucleoporin 214. (2089 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (325 aa)
RNF2Ring finger protein 2. (336 aa)
PHC3Polyhomeotic homolog 3. (983 aa)
RANBP2RAN binding protein 2. (3196 aa)
NUP35Nucleoporin 35. (278 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
NUP98Nucleoporin 98. (1817 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (367 aa)
ENSCATP00000019755Rad21_Rec8 domain-containing protein. (141 aa)
ENSCATP00000020360SP-RING-type domain-containing protein. (201 aa)
PIAS2Protein inhibitor of activated STAT 2. (619 aa)
SP110SP110 nuclear body protein. (550 aa)
SP140SP140 nuclear body protein. (848 aa)
TDGThymine DNA glycosylase. (410 aa)
ENSCATP00000022567Rad60-SLD domain-containing protein. (78 aa)
NUP88Nucleoporin 88. (741 aa)
RAD21RAD21 cohesin complex component. (631 aa)
NUP210Nucleoporin 210. (1887 aa)
PHC1Polyhomeotic homolog 1. (1003 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
MAGEB4MAGE family member B4. (268 aa)
ENSCATP00000024775Uncharacterized protein. (90 aa)
SP140LSP140 nuclear body protein like. (571 aa)
STAG1Stromal antigen 1. (1291 aa)
KCTD2Potassium channel tetramerization domain containing 2. (263 aa)
NUP50Nucleoporin 50. (468 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (561 aa)
SCMH1Scm polycomb group protein homolog 1. (660 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (419 aa)
NUP62CLNucleoporin 62 C-terminal like. (184 aa)
CBX8Chromobox 8. (385 aa)
ENSCATP00000029025annotation not available (87 aa)
ENSCATP00000029205Rad60-SLD domain-containing protein. (74 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (377 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (237 aa)
ENSCATP00000030652Ubiquitin-like domain-containing protein. (136 aa)
CBX2Chromobox 2. (530 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
PIAS4Protein inhibitor of activated STAT 4. (515 aa)
ENSCATP00000031206Ubiquitin-like domain-containing protein. (128 aa)
NUP160Nucleoporin 160. (1436 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
SCML2Scm polycomb group protein like 2. (701 aa)
NUP43WD_REPEATS_REGION domain-containing protein. (380 aa)
ENSCATP00000032866Uncharacterized protein. (66 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
NUP42Nucleoporin 42. (435 aa)
NUP188Nucleoporin 188. (1751 aa)
NSMCE2SP-RING-type domain-containing protein. (246 aa)
WRNWRN RecQ like helicase. (1418 aa)
TPRTranslocated promoter region, nuclear basket protein. (2439 aa)
LOC105593367Uncharacterized protein. (1225 aa)
BLMBLM RecQ like helicase. (1416 aa)
ENSCATP00000035593Rad60-SLD domain-containing protein. (75 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
RAD52RAD52 homolog, DNA repair protein. (397 aa)
NUP54Nucleoporin 54. (508 aa)
ENSCATP00000036401Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (262 aa)
LOC105584067RING-type domain-containing protein. (334 aa)
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4801 aa)
NUP153Nucleoporin 153. (1515 aa)
SUMO3Ubiquitin-like domain-containing protein. (127 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
MAGEB6MAGE family member B6. (407 aa)
ENSCATP00000038940Uncharacterized protein. (566 aa)
SHLD1Shieldin complex subunit 1. (254 aa)
NUP37Nucleoporin 37. (326 aa)
NUP133Nucleoporin 133. (1156 aa)
RNF169Ring finger protein 169. (708 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
NUP62Nucleoporin 62. (338 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1017 aa)
SMC3Structural maintenance of chromosomes 3. (1007 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
NDC1NDC1 transmembrane nucleoporin. (674 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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