39 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYK	Non-specific protein-tyrosine kinase. (637 aa)
	EFS	Embryonal Fyn-associated substrate. (561 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	SRC	Tyrosine-protein kinase. (644 aa)
	VWF	Von Willebrand factor. (2812 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1068 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1158 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSCATP00000007407	PID domain-containing protein. (502 aa)
	NEDD9	Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
	FGA	Fibrinogen alpha chain. (863 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (925 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	TLN1	Talin 1. (2546 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (534 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1011 aa)
	CASS4	Cas scaffold protein family member 4. (786 aa)
	ITGA2B	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
	FN1	Fibronectin 1. (2477 aa)
	FGB	Fibrinogen beta chain. (491 aa)
	LOC105585293	Uncharacterized protein. (290 aa)
	ENSCATP00000026377	Uncharacterized protein. (170 aa)
	SHC1	SHC adaptor protein 1. (584 aa)
	BCAR1	BCAR1 scaffold protein, Cas family member. (916 aa)
	FGG	Fibrinogen gamma chain. (453 aa)
	TLN2	Talin 2. (2542 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	APBB1IP	Amyloid beta precursor protein binding family B member 1 interacting protein. (665 aa)
	CRK	CRK proto-oncogene, adaptor protein. (304 aa)
	RASGRP2	RAS guanyl releasing protein 2. (610 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (730 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	RASGRP1	RAS guanyl releasing protein 1. (837 aa)
	RAP1B	Uncharacterized protein. (184 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor like 1. (662 aa)
	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1311 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	BCAR1	ENSCATP00000006645	ENSCATP00000030187	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCAR1 scaffold protein, Cas family member.	0.430
AKT1	CRK	ENSCATP00000006645	ENSCATP00000038333	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CRK proto-oncogene, adaptor protein.	0.448
AKT1	CSK	ENSCATP00000006645	ENSCATP00000014453	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.453
AKT1	GRB2	ENSCATP00000006645	ENSCATP00000042750	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor bound protein 2.	0.563
AKT1	PDPK1	ENSCATP00000006645	ENSCATP00000018326	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.988
AKT1	PTK2	ENSCATP00000006645	ENSCATP00000005130	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.570
AKT1	SOS1	ENSCATP00000006645	ENSCATP00000004020	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.478
AKT1	SRC	ENSCATP00000006645	ENSCATP00000004115	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.787
AKT1	TLN1	ENSCATP00000006645	ENSCATP00000015006	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Talin 1.	0.410
APBB1IP	BCAR1	ENSCATP00000036402	ENSCATP00000030187	Amyloid beta precursor protein binding family B member 1 interacting protein.	BCAR1 scaffold protein, Cas family member.	0.556
APBB1IP	CASS4	ENSCATP00000036402	ENSCATP00000020039	Amyloid beta precursor protein binding family B member 1 interacting protein.	Cas scaffold protein family member 4.	0.423
APBB1IP	CRK	ENSCATP00000036402	ENSCATP00000038333	Amyloid beta precursor protein binding family B member 1 interacting protein.	CRK proto-oncogene, adaptor protein.	0.630
APBB1IP	CSK	ENSCATP00000036402	ENSCATP00000014453	Amyloid beta precursor protein binding family B member 1 interacting protein.	Tyrosine-protein kinase.	0.503
APBB1IP	EFS	ENSCATP00000036402	ENSCATP00000002918	Amyloid beta precursor protein binding family B member 1 interacting protein.	Embryonal Fyn-associated substrate.	0.423
APBB1IP	ENSCATP00000007407	ENSCATP00000036402	ENSCATP00000007407	Amyloid beta precursor protein binding family B member 1 interacting protein.	PID domain-containing protein.	0.484
APBB1IP	ENSCATP00000026377	ENSCATP00000036402	ENSCATP00000026377	Amyloid beta precursor protein binding family B member 1 interacting protein.	Uncharacterized protein.	0.950
APBB1IP	GRB2	ENSCATP00000036402	ENSCATP00000042750	Amyloid beta precursor protein binding family B member 1 interacting protein.	Growth factor receptor bound protein 2.	0.718
APBB1IP	ITGB3	ENSCATP00000036402	ENSCATP00000016198	Amyloid beta precursor protein binding family B member 1 interacting protein.	Integrin beta; Belongs to the integrin beta chain family.	0.476
APBB1IP	LOC105585293	ENSCATP00000036402	ENSCATP00000024270	Amyloid beta precursor protein binding family B member 1 interacting protein.	Uncharacterized protein.	0.484
APBB1IP	NEDD9	ENSCATP00000036402	ENSCATP00000010845	Amyloid beta precursor protein binding family B member 1 interacting protein.	Neural precursor cell expressed, developmentally down-regulated 9.	0.535