STRINGSTRING
PFDN6 PFDN6 STAT3 STAT3 ERMARD ERMARD ARFGEF1 ARFGEF1 TUBA1C TUBA1C RGS9 RGS9 NOP56 NOP56 ACTB ACTB LOC105596933 LOC105596933 CCT5 CCT5 ENSCATP00000012545 ENSCATP00000012545 TUBA8 TUBA8 FBXO6 FBXO6 ENSCATP00000011418 ENSCATP00000011418 ARL2 ARL2 VBP1 VBP1 LONP2 LONP2 TBCE TBCE ENSCATP00000008723 ENSCATP00000008723 GNB3 GNB3 LOC105581531 LOC105581531 CSNK2A2 CSNK2A2 ENSCATP00000007662 ENSCATP00000007662 GNB5 GNB5 PFDN1 PFDN1 HDAC3 HDAC3 GNG5 GNG5 ENSCATP00000004605 ENSCATP00000004605 ENSCATP00000004528 ENSCATP00000004528 AP3M1 AP3M1 RGS11 RGS11 GNG12 GNG12 GNB1 GNB1 LOC105571676 LOC105571676 GNB4 GNB4 ENSCATP00000001853 ENSCATP00000001853 FBXW5 FBXW5 ENSCATP00000001050 ENSCATP00000001050 FKBP9 FKBP9 KIF13A KIF13A TBCB TBCB GNG11 GNG11 GNA14 GNA14 GNAQ GNAQ LOC105582850 LOC105582850 CCNE2 CCNE2 TBCD TBCD GNA15 GNA15 FBXW10 FBXW10 CSNK2A1 CSNK2A1 TBCC TBCC ENSCATP00000040481 ENSCATP00000040481 PFDN4 PFDN4 CCT2 CCT2 ENSCATP00000039367 ENSCATP00000039367 FBXW2 FBXW2 AP3M2 AP3M2 FBXW4 FBXW4 ENSCATP00000038494 ENSCATP00000038494 CCT7 CCT7 LOC105584454 LOC105584454 KIFC3 KIFC3 FBXL5 FBXL5 PFDN5 PFDN5 CSNK2B CSNK2B RGS6 RGS6 TCP1 TCP1 ENSCATP00000035075 ENSCATP00000035075 GNGT2 GNGT2 XRN2 XRN2 FBXW7 FBXW7 CCT6B CCT6B SPHK1 SPHK1 ENSCATP00000033138 ENSCATP00000033138 GBA GBA GNB2 GNB2 GNG2 GNG2 TP53 TP53 CCT4 CCT4 FBXO4 FBXO4 CCT8 CCT8 ENSCATP00000031508 ENSCATP00000031508 GNG3 GNG3 GNG8 GNG8 TUBB6 TUBB6 DCAF7 DCAF7 GNA11 GNA11 GNG4 GNG4 WRAP53 WRAP53 SKIV2L SKIV2L TUBAL3 TUBAL3 PDC PDC CCNE1 CCNE1 ENSCATP00000026030 ENSCATP00000026030 TUBB1 TUBB1 ENSCATP00000025852 ENSCATP00000025852 FBXW9 FBXW9 LOC105601524 LOC105601524 ARFGEF2 ARFGEF2 ENSCATP00000024568 ENSCATP00000024568 FBXL3 FBXL3 CCT6A CCT6A RGS7 RGS7 PDCL PDCL ENSCATP00000022192 ENSCATP00000022192 PFDN2 PFDN2 USP11 USP11 GNGT1 GNGT1 FKBP10 FKBP10 ENSCATP00000021304 ENSCATP00000021304 TBCA TBCA GAPDHS GAPDHS ENSCATP00000019657 ENSCATP00000019657 TUBA4A TUBA4A ENSCATP00000018990 ENSCATP00000018990 GNG13 GNG13 CCT3 CCT3 FBXO44 FBXO44
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PFDN6Prefoldin subunit 6. (129 aa)
STAT3Signal transducer and activator of transcription. (777 aa)
ERMARDER membrane associated RNA degradation. (669 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1852 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
RGS9Regulator of G protein signaling 9. (674 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
ACTBUncharacterized protein. (375 aa)
LOC105596933Uncharacterized protein. (521 aa)
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
ENSCATP00000012545Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (112 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
FBXO6F-box protein 6. (293 aa)
ENSCATP00000011418Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (70 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
VBP1VHL binding protein 1. (239 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (825 aa)
TBCEUncharacterized protein. (555 aa)
ENSCATP00000008723T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (53 aa)
GNB3G protein subunit beta 3. (340 aa)
LOC105581531Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
ENSCATP00000007662Tubulin-specific chaperone A; Belongs to the TBCA family. (108 aa)
GNB5G protein subunit beta 5. (409 aa)
PFDN1Prefoldin subunit 1. (122 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSCATP00000004605Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
ENSCATP00000004528Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (140 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
RGS11Regulator of G protein signaling 11. (467 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB1G protein subunit beta 1. (340 aa)
LOC105571676Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSCATP00000001853Uncharacterized protein. (293 aa)
FBXW5F-box and WD repeat domain containing 5. (641 aa)
ENSCATP00000001050G protein gamma domain-containing protein. (63 aa)
FKBP9Peptidylprolyl isomerase. (623 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1763 aa)
TBCBCAP-Gly domain-containing protein. (244 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAQUncharacterized protein. (359 aa)
LOC105582850T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (467 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
TBCDTubulin folding cofactor D. (1246 aa)
GNA15G protein subunit alpha 15. (374 aa)
FBXW10WD_REPEATS_REGION domain-containing protein. (1061 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
TBCCTubulin folding cofactor C. (359 aa)
ENSCATP00000040481Uncharacterized protein. (411 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
CCT2Chaperonin containing TCP1 subunit 2. (589 aa)
ENSCATP00000039367Uncharacterized protein. (360 aa)
FBXW2F-box and WD repeat domain containing 2. (454 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
FBXW4F-box and WD repeat domain containing 4. (410 aa)
ENSCATP00000038494Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (481 aa)
LOC105584454Uncharacterized protein. (152 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (913 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
PFDN5Uncharacterized protein. (160 aa)
CSNK2BUncharacterized protein. (298 aa)
RGS6Regulator of G protein signaling 6. (505 aa)
TCP1Uncharacterized protein. (556 aa)
ENSCATP00000035075Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (535 aa)
SPHK1Sphingosine kinase 1. (470 aa)
ENSCATP00000033138Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GBAGlucosylceramidase. (344 aa)
GNB2G protein subunit beta 2. (340 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
CCT4T-complex protein 1 subunit delta. (509 aa)
FBXO4F-box protein 4. (387 aa)
CCT8Uncharacterized protein. (548 aa)
ENSCATP00000031508Uncharacterized protein. (318 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
GNA11G protein subunit alpha 11. (394 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
WRAP53WD repeat containing antisense to TP53. (549 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PDCPhosducin. (246 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
ENSCATP00000026030G protein gamma domain-containing protein. (59 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ENSCATP00000025852Uncharacterized protein. (506 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
LOC105601524Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)
ENSCATP00000024568Uncharacterized protein. (450 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
CCT6AUncharacterized protein. (566 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
PDCLPhosducin like. (301 aa)
ENSCATP00000022192CAP-Gly domain-containing protein. (231 aa)
PFDN2Prefoldin subunit 2. (154 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (970 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
FKBP10Peptidylprolyl isomerase. (584 aa)
ENSCATP00000021304Glucosylceramidase. (480 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (131 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
ENSCATP00000019657Uncharacterized protein; Belongs to the actin family. (368 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
ENSCATP00000018990Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
FBXO44Uncharacterized protein. (255 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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