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CLTC CLTC SH3GL2 SH3GL2 ENSCATP00000001293 ENSCATP00000001293 CLTA CLTA PIK3C2A PIK3C2A SNX2 SNX2 BLOC1S3 BLOC1S3 ENSCATP00000004890 ENSCATP00000004890 PUM1 PUM1 AP4B1 AP4B1 BLOC1S4 BLOC1S4 AP1M2 AP1M2 TBC1D9 TBC1D9 VAMP8 VAMP8 GOLGB1 GOLGB1 AP1S1 AP1S1 HIP1R HIP1R NECAP1 NECAP1 TPD52L2 TPD52L2 AP3B2 AP3B2 AP4E1 AP4E1 TXNDC5 TXNDC5 AP3S1 AP3S1 CLINT1 CLINT1 VAMP7 VAMP7 SBSN SBSN FTL FTL DTNBP1 DTNBP1 YIPF6 YIPF6 SNX9 SNX9 CPD CPD SORT1 SORT1 ENSCATP00000019466 ENSCATP00000019466 TPD52L1 TPD52L1 SNX1 SNX1 ARF1 ARF1 ENSCATP00000020884 ENSCATP00000020884 MTSS2 MTSS2 ENSCATP00000021227 ENSCATP00000021227 AP1S3 AP1S3 ENSCATP00000022027 ENSCATP00000022027 DNAJC6 DNAJC6 ENSCATP00000022722 ENSCATP00000022722 TFRC TFRC TBC1D8B TBC1D8B SPAG5 SPAG5 TGOLN2 TGOLN2 HSPA8 HSPA8 VAMP2 VAMP2 LOC105571822 LOC105571822 TBC1D9B TBC1D9B GAK GAK OCRL OCRL MTSS1 MTSS1 LOC105592392 LOC105592392 AP3B1 AP3B1 SNX32 SNX32 ENSCATP00000031565 ENSCATP00000031565 DNM2 DNM2 AP1G1 AP1G1 AP1S2 AP1S2 NAPA NAPA ARRB1 ARRB1 BLOC1S6 BLOC1S6 SH3D19 SH3D19 IGF2R IGF2R TBC1D8 TBC1D8 LOC105594535 LOC105594535 RAB5C RAB5C HCLS1 HCLS1 AP1B1 AP1B1 SNX5 SNX5 AP1M1 AP1M1 TPD52 TPD52 ACBD3 ACBD3 SNAPIN SNAPIN SNX6 SNX6 LOC105574579 LOC105574579 PICALM PICALM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
ENSCATP00000001293Uncharacterized protein; Belongs to the heat shock protein 70 family. (604 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
SNX2Sorting nexin 2. (519 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa)
ENSCATP00000004890PX domain-containing protein. (199 aa)
PUM1Pumilio RNA binding family member 1. (1161 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
BLOC1S4Biogenesis of lysosomal organelles complex 1 subunit 4. (216 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (419 aa)
TBC1D9TBC1 domain family member 9. (1236 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
GOLGB1Golgin B1. (3270 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
NECAP1NECAP endocytosis associated 1. (275 aa)
TPD52L2TPD52 like 2. (229 aa)
AP3B2AP-3 complex subunit beta. (1102 aa)
AP4E1AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1125 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (363 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (193 aa)
CLINT1Clathrin interactor 1. (643 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
SBSNSuprabasin. (569 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
DTNBP1Dystrobrevin binding protein 1. (305 aa)
YIPF6Protein YIPF. (209 aa)
SNX9Sorting nexin. (596 aa)
CPDCarboxypeptidase D. (1378 aa)
SORT1Sortilin. (814 aa)
ENSCATP00000019466Uncharacterized protein; Belongs to the heat shock protein 70 family. (621 aa)
TPD52L1TPD52 like 1. (221 aa)
SNX1Sorting nexin 1. (557 aa)
ARF1Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ENSCATP00000020884PX domain-containing protein. (337 aa)
MTSS2MTSS I-BAR domain containing 2. (747 aa)
ENSCATP00000021227Uncharacterized protein. (212 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
ENSCATP00000022027Uncharacterized protein; Belongs to the heat shock protein 70 family. (594 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (970 aa)
ENSCATP00000022722Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
TFRCTransferrin receptor. (755 aa)
TBC1D8BTBC1 domain family member 8B. (1107 aa)
SPAG5Sperm associated antigen 5. (1194 aa)
TGOLN2Trans-golgi network protein 2. (431 aa)
HSPA8Uncharacterized protein. (129 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
LOC105571822Uncharacterized protein; Belongs to the heat shock protein 70 family. (534 aa)
TBC1D9BTBC1 domain family member 9B. (1255 aa)
GAKCyclin G associated kinase. (1311 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (1014 aa)
MTSS1MTSS I-BAR domain containing 1. (799 aa)
LOC105592392Clat_adaptor_s domain-containing protein. (394 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (391 aa)
ENSCATP00000031565Uncharacterized protein. (357 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
AP1G1AP-1 complex subunit gamma. (744 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
NAPANSF attachment protein alpha. (295 aa)
ARRB1Arrestin beta 1. (418 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
SH3D19SH3 domain containing 19. (1046 aa)
IGF2RInsulin like growth factor 2 receptor. (2445 aa)
TBC1D8TBC1 domain family member 8. (1155 aa)
LOC105594535Clat_adaptor_s domain-containing protein. (203 aa)
RAB5CRAB5C, member RAS oncogene family. (246 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
AP1B1AP complex subunit beta. (949 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (405 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa)
TPD52Uncharacterized protein. (274 aa)
ACBD3Acyl-CoA binding domain containing 3. (528 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (410 aa)
LOC105574579Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (181 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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