STRINGSTRING
ENSCATP00000017436 ENSCATP00000017436 ATF2 ATF2 MAPK8 MAPK8 PPP2CB PPP2CB MEF2A MEF2A ENSCATP00000004894 ENSCATP00000004894 ATF7 ATF7 PPP2R1B PPP2R1B MAPK11 MAPK11 MAPK3 MAPK3 VRK3 VRK3 RPS6KA2 RPS6KA2 ENSCATP00000014838 ENSCATP00000014838 DUSP4 DUSP4 MAPK1 MAPK1 ELK1 ELK1 RPS6KA1 RPS6KA1 MAPK9 MAPK9 MAPK7 MAPK7 LOC105585327 LOC105585327 ATF1 ATF1 DUSP7 DUSP7 PPP4R1 PPP4R1 RELCH RELCH RPS6KA3 RPS6KA3 CREM CREM ENSCATP00000027386 ENSCATP00000027386 CREB1 CREB1 RPS6KA5 RPS6KA5 FNBP4 FNBP4 CREB5 CREB5 MAPKAPK2 MAPKAPK2 PPP2CA PPP2CA FOSL2 FOSL2 PPP2R5D PPP2R5D PPP2R1A PPP2R1A DUSP3 DUSP3 PPP4R4 PPP4R4 MEF2C MEF2C DUSP6 DUSP6 MAPK15 MAPK15 MAPK14 MAPK14 MAPK10 MAPK10 FOS FOS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000017436ETS domain-containing protein. (394 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
MEF2AMyocyte enhancer factor 2A. (504 aa)
ENSCATP00000004894ETS domain-containing protein. (421 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
VRK3VRK serine/threonine kinase 3. (451 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ENSCATP00000014838ETS domain-containing protein. (418 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ELK1ETS domain-containing protein. (428 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
LOC105585327WRNPLPNID domain-containing protein. (954 aa)
ATF1Activating transcription factor 1. (270 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (907 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
RPS6KA3Ribosomal protein S6 kinase. (732 aa)
CREMcAMP responsive element modulator. (330 aa)
ENSCATP00000027386Uncharacterized protein. (109 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
RPS6KA5Non-specific serine/threonine protein kinase. (896 aa)
FNBP4Formin binding protein 4. (1017 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (872 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK10Mitogen-activated protein kinase. (474 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (18%) [HD]