STRINGSTRING
PIK3R3 PIK3R3 SHC1 SHC1 PIK3CA PIK3CA ENSCATP00000024947 ENSCATP00000024947 LOC105585293 LOC105585293 PIK3CB PIK3CB PIK3R2 PIK3R2 HAVCR2 HAVCR2 IL2 IL2 ENSCATP00000021628 ENSCATP00000021628 IL5RA IL5RA GAB2 GAB2 SASH3 SASH3 PTK2B PTK2B LOC105591569 LOC105591569 STAT3 STAT3 IL5 IL5 IL2RG IL2RG IL21 IL21 GAB4 GAB4 IL9 IL9 IL9R IL9R JAK2 JAK2 JAK3 JAK3 LCK LCK GRB2 GRB2 IL21R IL21R SOS2 SOS2 CSF2 CSF2 IL15 IL15 PIK3CD PIK3CD JAK1 JAK1 IL3 IL3 ENSCATP00000007407 ENSCATP00000007407 IL2RA IL2RA STAT4 STAT4 INPP5D INPP5D SOS1 SOS1 PTPN6 PTPN6 PIK3R1 PIK3R1 STAT5B STAT5B SYK SYK CSF2RA CSF2RA INPPL1 INPPL1 STAT5A STAT5A IL2RB IL2RB STAT1 STAT1 LOC105591578 LOC105591578 CSF2RB CSF2RB IL15RA IL15RA SAMSN1 SAMSN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
SHC1SHC adaptor protein 1. (584 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
ENSCATP00000024947Uncharacterized protein. (303 aa)
LOC105585293Uncharacterized protein. (290 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
PIK3R2Uncharacterized protein. (624 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa)
ENSCATP00000021628Uncharacterized protein. (166 aa)
IL5RAInterleukin 5 receptor subunit alpha. (420 aa)
GAB2GRB2 associated binding protein 2. (676 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
LOC105591569Galectin. (296 aa)
STAT3Signal transducer and activator of transcription. (777 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
GAB4GRB2 associated binding protein family member 4. (536 aa)
IL9Interleukin 9. (145 aa)
IL9RInterleukin 9 receptor. (514 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
LCKTyrosine-protein kinase. (540 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
IL21RInterleukin 21 receptor. (538 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa)
CSF2Colony stimulating factor 2. (144 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa)
ENSCATP00000007407PID domain-containing protein. (502 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
STAT4Signal transducer and activator of transcription. (710 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1184 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
CSF2RAColony stimulating factor 2 receptor alpha subunit. (361 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
STAT1Signal transducer and activator of transcription. (780 aa)
LOC105591578Galectin. (285 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (897 aa)
IL15RAInterleukin 15 receptor subunit alpha. (219 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (441 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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