STRINGSTRING
CBL CBL TEC TEC SYK SYK STAT5B STAT5B PTPN6 PTPN6 ENSCATP00000003364 ENSCATP00000003364 SOS1 SOS1 INPP5D INPP5D ENSCATP00000005869 ENSCATP00000005869 LOC105576738 LOC105576738 IL2RA IL2RA LOC105579396 LOC105579396 LOC105595668 LOC105595668 ENSCATP00000007407 ENSCATP00000007407 JAK3 JAK3 YWHAZ YWHAZ JAK2 JAK2 RAPGEF1 RAPGEF1 LYN LYN ENSCATP00000012914 ENSCATP00000012914 GAB4 GAB4 IL2RG IL2RG UBA52 UBA52 IL5 IL5 VAV1 VAV1 PTPN11 PTPN11 GAB2 GAB2 HCK HCK IL5RA IL5RA IL2 IL2 FYN FYN ENSCATP00000023795 ENSCATP00000023795 PIK3R2 PIK3R2 PIK3CB PIK3CB LOC105585293 LOC105585293 ENSCATP00000024947 ENSCATP00000024947 YES1 YES1 PIK3CA PIK3CA SHC1 SHC1 PIK3R3 PIK3R3 PIK3R1 PIK3R1 CSF2RA CSF2RA ENSCATP00000031033 ENSCATP00000031033 INPPL1 INPPL1 STAT5A STAT5A IL2RB IL2RB CRKL CRKL ENSCATP00000034768 ENSCATP00000034768 CSF2RB CSF2RB ENSCATP00000035134 ENSCATP00000035134 IL3 IL3 JAK1 JAK1 ENSCATP00000037714 ENSCATP00000037714 PIK3CD PIK3CD CRK CRK CSF2 CSF2 RPS27A RPS27A GRB2 GRB2 ENSCATP00000043644 ENSCATP00000043644 ENSCATP00000044421 ENSCATP00000044421
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBLCbl proto-oncogene. (907 aa)
TECTyrosine-protein kinase. (630 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
ENSCATP0000000336414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1184 aa)
ENSCATP00000005869Uncharacterized protein. (526 aa)
LOC105576738Ubiquitin-like domain-containing protein. (134 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
LOC105595668Ubiquitin-like domain-containing protein. (126 aa)
ENSCATP00000007407PID domain-containing protein. (502 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1303 aa)
LYNTyrosine-protein kinase. (507 aa)
ENSCATP00000012914Tyrosine-protein kinase. (399 aa)
GAB4GRB2 associated binding protein family member 4. (536 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
VAV1Vav guanine nucleotide exchange factor 1. (856 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (552 aa)
GAB2GRB2 associated binding protein 2. (676 aa)
HCKTyrosine-protein kinase. (504 aa)
IL5RAInterleukin 5 receptor subunit alpha. (420 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSCATP0000002379514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (238 aa)
PIK3R2Uncharacterized protein. (624 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
LOC105585293Uncharacterized protein. (290 aa)
ENSCATP00000024947Uncharacterized protein. (303 aa)
YES1Tyrosine-protein kinase. (543 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
SHC1SHC adaptor protein 1. (584 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CSF2RAColony stimulating factor 2 receptor alpha subunit. (361 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (897 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
ENSCATP0000003771414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (232 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CSF2Colony stimulating factor 2. (144 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSCATP00000043644Ubiquitin-like domain-containing protein. (120 aa)
ENSCATP00000044421Uncharacterized protein. (441 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.