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| | HMGB2 | Uncharacterized protein. (206 aa) |
| | H1-5 | Histone cluster 1 H1 family member b. (226 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | ENSCATP00000004934 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1068 aa) |
| | HMGB1 | High mobility group box 1. (215 aa) |
| | UBE2L5 | Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | LOC105595225 | FIIND domain-containing protein. (515 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) |
| | NMT1 | Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (543 aa) |
| | H1-0 | H1 histone family member 0. (194 aa) |
| | LOC105576738 | Ubiquitin-like domain-containing protein. (134 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | H1-4 | Histone cluster 1 H1 family member e. (219 aa) |
| | LOC105588083 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa) |
| | ADD1 | Adducin 1. (768 aa) |
| | LOC105589984 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC105579396 | Ubiquitin-like domain-containing protein. (156 aa) |
| | DCC | DCC netrin 1 receptor. (1447 aa) |
| | LOC105595668 | Ubiquitin-like domain-containing protein. (126 aa) |
| | ENSCATP00000007583 | Uncharacterized protein. (188 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (336 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa) |
| | TMEM198 | Transmembrane protein 198. (360 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | TTC6 | TPR_REGION domain-containing protein. (1886 aa) |
| | YWHAZ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa) |
| | ENSCATP00000008212 | Uncharacterized protein. (145 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | DSG3 | Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (999 aa) |
| | STK24 | Serine/threonine kinase 24. (417 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (212 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (471 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ENSCATP00000010732 | CSN8_PSD8_EIF3K domain-containing protein. (249 aa) |
| | ARHGAP10 | Rho GTPase activating protein 10. (786 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | BCAP29 | B cell receptor associated protein 29. (317 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (519 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) |
| | ENSCATP00000029662 | Uncharacterized protein. (305 aa) |
| | ENSCATP00000029366 | Uncharacterized protein. (101 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | ENSCATP00000029075 | IRF tryptophan pentad repeat domain-containing protein. (140 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | ENSCATP00000028876 | Uncharacterized protein. (89 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | GZMB | Granzyme B; Belongs to the peptidase S1 family. (281 aa) |
| | GSDME | Gasdermin E. (495 aa) |
| | SEPTIN1 | Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (403 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | OPA1 | OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa) |
| | KPNB1 | Karyopherin subunit beta 1. (876 aa) |
| | UNC5A | Unc-5 netrin receptor A. (898 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (515 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (505 aa) |
| | BCL2L10 | Uncharacterized protein. (194 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1134 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | ENSCATP00000045432 | Uncharacterized protein. (173 aa) |
| | DSG2 | Desmoglein 2. (1118 aa) |
| | PSME4 | Proteasome activator subunit 4. (1792 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | GAS2 | Growth arrest specific 2. (314 aa) |
| | LMNTD2 | Lamin tail domain containing 2. (634 aa) |
| | DBNL | Drebrin like. (440 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | ENSCATP00000011232 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | SDCBP | Syndecan binding protein. (318 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa) |
| | HP1BP3 | Heterochromatin protein 1 binding protein 3. (521 aa) |
| | ENSCATP00000011745 | AAA domain-containing protein. (410 aa) |
| | TRADD | TNFRSF1A associated via death domain. (308 aa) |
| | ENSCATP00000011808 | Ubiquitin-like domain-containing protein. (130 aa) |
| | ENSCATP00000011971 | Uncharacterized protein. (191 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | ENSCATP00000012820 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (363 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (374 aa) |
| | ENSCATP00000013533 | Uncharacterized protein. (215 aa) |
| | APC | APC regulator of WNT signaling pathway. (2861 aa) |
| | PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | GSDMB | Gasdermin B. (370 aa) |
| | HMGB3 | Uncharacterized protein. (210 aa) |
| | LMNTD1 | Lamin tail domain containing 1. (413 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (441 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | ENSCATP00000014541 | Prot_ATP_ID_OB domain-containing protein. (172 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | LOC105595226 | FIIND domain-containing protein. (349 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSCATP00000015253 | AAA domain-containing protein. (373 aa) |
| | ENSCATP00000015286 | PDZ domain-containing protein. (251 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | ROCK1 | Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1337 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa) |
| | ENSCATP00000016334 | Uncharacterized protein. (338 aa) |
| | ENSCATP00000016481 | AAA domain-containing protein. (370 aa) |
| | ENSCATP00000016559 | PDZ domain-containing protein. (294 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | CDC37 | Cell division cycle 37. (378 aa) |
| | BID | BH3 interacting domain death agonist. (244 aa) |
| | DIABLO | Uncharacterized protein. (239 aa) |
| | LOC105579883 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (238 aa) |
| | STAT3 | Signal transducer and activator of transcription. (777 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (249 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) |
| | SEPTIN4 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (985 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | CASP5 | Caspase 5; Belongs to the peptidase C14A family. (355 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | LMNB2 | Lamin B2; Belongs to the intermediate filament family. (621 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (728 aa) |
| | SCIN | Scinderin. (706 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (293 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | ENSCATP00000020255 | Dynein light chain. (83 aa) |
| | ENSCATP00000020357 | AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | DAPK1 | Death associated protein kinase 1. (1440 aa) |
| | DYNLL1 | Dynein light chain. (89 aa) |
| | STK25 | Serine/threonine kinase 25. (426 aa) |
| | BNIP5 | BCL2 interacting protein 5. (651 aa) |
| | ACIN1 | Apoptotic chromatin condensation inducer 1. (1340 aa) |
| | BMX | Tyrosine-protein kinase. (679 aa) |
| | ENSCATP00000043644 | Ubiquitin-like domain-containing protein. (120 aa) |
| | CARD18 | Caspase recruitment domain family member 18. (92 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (508 aa) |
| | CHMP4B | Charged multivesicular body protein 4B. (224 aa) |
| | LOC105589886 | Uncharacterized protein. (339 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | CLSPN | Claspin. (1342 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | ENSCATP00000042870 | Uncharacterized protein. (348 aa) |
| | ENSCATP00000042857 | Dynein light chain. (79 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (233 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (213 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1090 aa) |
| | DAPK2 | Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (474 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | ENSCATP00000042056 | Dynein light chain. (74 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSCATP00000041581 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | ENSCATP00000041490 | AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa) |
| | BCAP31 | B cell receptor associated protein 31. (313 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | LOC105571593 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | MAP2 | Microtubule-associated protein. (1914 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2301 aa) |
| | ENSCATP00000040576 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa) |
| | ENSCATP00000040310 | ANK_REP_REGION domain-containing protein. (159 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | MLKL | Mixed lineage kinase domain like pseudokinase. (477 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (315 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | TFDP1 | Transcription factor. (417 aa) |
| | DFFA | DNA fragmentation factor subunit alpha. (331 aa) |
| | LOC105587074 | Uncharacterized protein. (186 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (379 aa) |
| | NPVF | Neuropeptide VF precursor. (196 aa) |
| | ENSCATP00000038453 | Uncharacterized protein; Belongs to the peptidase C14A family. (262 aa) |
| | IGDCC4 | Immunoglobulin superfamily DCC subclass member 4. (1250 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | DAPK3 | Death associated protein kinase 3. (422 aa) |
| | PSMA4 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (831 aa) |
| | ENSCATP00000037714 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (232 aa) |
| | CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa) |
| | PSMB6 | Proteasome subunit beta. (285 aa) |
| | ENSCATP00000037470 | AAA domain-containing protein. (389 aa) |
| | UNC5B | Unc-5 netrin receptor B. (904 aa) |
| | C1QBP | Complement C1q binding protein. (281 aa) |
| | IGDCC3 | Immunoglobulin superfamily DCC subclass member 3. (809 aa) |
| | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1418 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (271 aa) |
| | SATB1 | DNA-binding protein SATB. (794 aa) |
| | H1-8 | H1 histone family member O oocyte specific. (338 aa) |
| | SEPTIN5 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa) |
| | ENSCATP00000035134 | Ubiquitin-like domain-containing protein. (146 aa) |
| | ENSCATP00000035052 | Uncharacterized protein. (211 aa) |
| | SH3GLB1 | SH3 domain containing GRB2 like, endophilin B1. (402 aa) |
| | ENSCATP00000034768 | Ubiquitin-like domain-containing protein. (144 aa) |
| | ENSCATP00000034742 | JAB_MPN domain-containing protein. (166 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa) |
| | PDCD6IP | Programmed cell death 6 interacting protein. (873 aa) |
| | GSDMD | Gasdermin D. (532 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (438 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | ENSCATP00000032552 | Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (109 aa) |
| | OMA1 | OMA1 zinc metallopeptidase. (524 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (445 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | ENSCATP00000031033 | Ubiquitin-like domain-containing protein. (149 aa) |
| | SH3GLB2 | SH3 domain containing GRB2 like, endophilin B2. (404 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (715 aa) |
| | SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2498 aa) |
| | TJP3 | Tight junction protein 3; Belongs to the MAGUK family. (917 aa) |
| | AVEN | Apoptosis and caspase activation inhibitor. (355 aa) |
| | MAPT | Microtubule-associated protein. (776 aa) |
| | IRF1 | Interferon regulatory factor. (325 aa) |
| | BMF | Bcl2 modifying factor. (184 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | STK26 | Serine/threonine kinase 26. (438 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa) |
| | CHMP3 | Charged multivesicular body protein 3. (221 aa) |
| | ENSCATP00000024481 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) |
| | MDP1 | Magnesium dependent phosphatase 1. (164 aa) |
| | PKP1 | Plakophilin 1. (744 aa) |
| | TFDP2 | Transcription factor. (446 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | CAPG | Capping actin protein, gelsolin like. (348 aa) |
| | ENSCATP00000023795 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (238 aa) |
| | DSG1 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (938 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1742 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | LMNB1 | Lamin B1; Belongs to the intermediate filament family. (586 aa) |
| | DSP | Desmoplakin. (2272 aa) |
| | LOC105588756 | Caspase recruitment domain family member 17. (110 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | ENSCATP00000021172 | Uncharacterized protein. (278 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | ENSCATP00000000117 | Uncharacterized protein. (93 aa) |
| | ENSCATP00000000678 | Uncharacterized protein. (211 aa) |
| | TJP2 | Uncharacterized protein; Belongs to the MAGUK family. (1247 aa) |
| | DFFB | DNA fragmentation factor subunit beta. (337 aa) |
| | LOC105595720 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | HMGB4 | High mobility group box 4. (191 aa) |
| | ENSCATP00000001361 | DUF4203 domain-containing protein. (100 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1403 aa) |
| | ENSCATP00000001452 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (98 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | FNTA | Farnesyltransferase, CAAX box, alpha. (379 aa) |
| | PLEC | Plectin. (4684 aa) |
| | GSN | Gelsolin. (809 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | ENSCATP00000003010 | Uncharacterized protein. (189 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | ENSCATP00000003364 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa) |
| | ENSCATP00000003394 | Transcription factor. (393 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (214 aa) |
| | ENSCATP00000003644 | ANK_REP_REGION domain-containing protein. (116 aa) |
| | ENSCATP00000003774 | Uncharacterized protein. (291 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (862 aa) |
| | ENSCATP00000004066 | Uncharacterized protein. (189 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (328 aa) |
