STRINGSTRING
GNAS GNAS ADCY10 ADCY10 TUBB6 TUBB6 ENSCATP00000031033 ENSCATP00000031033 WDR19 WDR19 GLIS3 GLIS3 PSMC1 PSMC1 TUBA1B TUBA1B PSMA6 PSMA6 PSMD8 PSMD8 PSMD1 PSMD1 RPGRIP1L RPGRIP1L PSMD2 PSMD2 IFT52 IFT52 ADCY5 ADCY5 GLI3 GLI3 TUBB1 TUBB1 RBX1 RBX1 PSMB1 PSMB1 MKS1 MKS1 IFT140 IFT140 CSNK1A1L CSNK1A1L ENSCATP00000023911 ENSCATP00000023911 GSK3B GSK3B GLI2 GLI2 PSMD9 PSMD9 TTC21A TTC21A PSME1 PSME1 ENSCATP00000021172 ENSCATP00000021172 ADCY8 ADCY8 CSNK1A1 CSNK1A1 PSMC5 PSMC5 ADCY2 ADCY2 ENSCATP00000020357 ENSCATP00000020357 PSMB7 PSMB7 ENSCATP00000020004 ENSCATP00000020004 PTRHD1 PTRHD1 SMO SMO PSMD10 PSMD10 IFT172 IFT172 TUBA4A TUBA4A PSMA5 PSMA5 PTCH1 PTCH1 PSMD12 PSMD12 PSMB10 PSMB10 PDCD2L PDCD2L LOC105579883 LOC105579883 IFT88 IFT88 ENSCATP00000016805 ENSCATP00000016805 UBA52 UBA52 PDCD2 PDCD2 TULP2 TULP2 ENSCATP00000016481 ENSCATP00000016481 ADCY3 ADCY3 ENSCATP00000016334 ENSCATP00000016334 TUBA1C TUBA1C ADCY6 ADCY6 ENSCATP00000015253 ENSCATP00000015253 PSMB3 PSMB3 ENSCATP00000014541 ENSCATP00000014541 PSMC6 PSMC6 PSMD4 PSMD4 PRKAR1A PRKAR1A THAP7 THAP7 ADCY9 ADCY9 PSMD6 PSMD6 ENSCATP00000011971 ENSCATP00000011971 ENSCATP00000011808 ENSCATP00000011808 ENSCATP00000011745 ENSCATP00000011745 TTC21B TTC21B ENSCATP00000010732 ENSCATP00000010732 PSMA2 PSMA2 FUZ FUZ PSMB8 PSMB8 DYNC2H1 DYNC2H1 PSMD7 PSMD7 ADCY7 ADCY7 LOC105595668 LOC105595668 LOC105579396 LOC105579396 PSMC3 PSMC3 GPR161 GPR161 LOC105576738 LOC105576738 IFT122 IFT122 TEX52 TEX52 ENSCATP00000004934 ENSCATP00000004934 PSMF1 PSMF1 PSMA1 PSMA1 INTU INTU ITCH ITCH ENSCATP00000003644 ENSCATP00000003644 PSMA7 PSMA7 PSMB11 PSMB11 ENSCATP00000000117 ENSCATP00000000117 ADCY1 ADCY1 ADCY4 ADCY4 KIF3A KIF3A ENSCATP00000041490 ENSCATP00000041490 RPS27A RPS27A PSME3 PSME3 PSMD11 PSMD11 TULP1 TULP1 WDR35 WDR35 GLI1 GLI1 ENSCATP00000042937 ENSCATP00000042937 PSMB5 PSMB5 PSMD5 PSMD5 PRKAR2B PRKAR2B ENSCATP00000043644 ENSCATP00000043644 PRKACA PRKACA PSME2 PSME2 OFD1 OFD1 TUB TUB PSME4 PSME4 PRKAR1B PRKAR1B ENSCATP00000040310 ENSCATP00000040310 NUMBL NUMBL PSMD14 PSMD14 PSMC4 PSMC4 PRKACB PRKACB PSMD13 PSMD13 NUMB NUMB SKP1 SKP1 PSMB9 PSMB9 PSMA4 PSMA4 BTRC BTRC PSMB6 PSMB6 ENSCATP00000037470 ENSCATP00000037470 PSMD3 PSMD3 CUL1 CUL1 PRKAR2A PRKAR2A FOPNL FOPNL THAP6 THAP6 ENSCATP00000035134 ENSCATP00000035134 ENSCATP00000035052 ENSCATP00000035052 ENSCATP00000034768 ENSCATP00000034768 ENSCATP00000034742 ENSCATP00000034742 GLIS1 GLIS1 ENSCATP00000034003 ENSCATP00000034003 ENSCATP00000033713 ENSCATP00000033713 SUFU SUFU PSMA8 PSMA8 PSMC2 PSMC2 CNBD2 CNBD2 PSMA3 PSMA3 IFT57 IFT57 TULP3 TULP3 PSMB4 PSMB4 PSMB2 PSMB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNASGNAS complex locus. (1028 aa)
ADCY10Adenylate cyclase 10. (1609 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
WDR19WD repeat domain 19. (1343 aa)
GLIS3GLIS family zinc finger 3. (931 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (490 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
RPGRIP1LRPGRIP1 like. (1314 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
IFT52Intraflagellar transport 52. (437 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
GLI3GLI family zinc finger 3. (1580 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
RBX1Ring-box 1. (108 aa)
PSMB1Proteasome subunit beta. (241 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
IFT140Intraflagellar transport 140. (1475 aa)
CSNK1A1LCasein kinase 1 alpha 1 like. (243 aa)
ENSCATP00000023911Uncharacterized protein. (368 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa)
GLI2GLI family zinc finger 2. (1586 aa)
PSMD9PDZ domain-containing protein. (223 aa)
TTC21ATetratricopeptide repeat domain 21A. (1321 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSCATP00000021172Uncharacterized protein. (278 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (353 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ENSCATP00000020357AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSCATP00000020004Uncharacterized protein; Belongs to the SKP1 family. (198 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (139 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
IFT172Intraflagellar transport 172. (1730 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PTCH1Patched 1. (1452 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB10Proteasome subunit beta. (273 aa)
PDCD2LPDCD2_C domain-containing protein. (371 aa)
LOC105579883Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (238 aa)
IFT88Intraflagellar transport 88. (824 aa)
ENSCATP00000016805Protein kinase domain-containing protein. (324 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PDCD2Programmed cell death 2. (344 aa)
TULP2TUB like protein 2; Belongs to the TUB family. (519 aa)
ENSCATP00000016481AAA domain-containing protein. (370 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ENSCATP00000016334Uncharacterized protein. (338 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
ENSCATP00000015253AAA domain-containing protein. (373 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSCATP00000014541Prot_ATP_ID_OB domain-containing protein. (172 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (363 aa)
PRKAR1AUncharacterized protein. (381 aa)
THAP7THAP domain containing 7. (309 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSCATP00000011971Uncharacterized protein. (191 aa)
ENSCATP00000011808Ubiquitin-like domain-containing protein. (130 aa)
ENSCATP00000011745AAA domain-containing protein. (410 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
ENSCATP00000010732CSN8_PSD8_EIF3K domain-containing protein. (249 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
PSMB8Proteasome subunit beta. (276 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4314 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
LOC105595668Ubiquitin-like domain-containing protein. (126 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (592 aa)
LOC105576738Ubiquitin-like domain-containing protein. (134 aa)
IFT122Intraflagellar transport 122. (1241 aa)
TEX52Testis expressed 52. (305 aa)
ENSCATP00000004934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
INTUInturned planar cell polarity protein. (942 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
ENSCATP00000003644ANK_REP_REGION domain-containing protein. (116 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMB11Proteasome subunit beta. (300 aa)
ENSCATP00000000117Uncharacterized protein. (93 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (722 aa)
ENSCATP00000041490AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSME3Proteasome activator subunit 3. (265 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (542 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1197 aa)
GLI1GLI family zinc finger 1. (1106 aa)
ENSCATP00000042937MYND-type domain-containing protein. (217 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (508 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
ENSCATP00000043644Ubiquitin-like domain-containing protein. (120 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
PSME2Proteasome activator subunit 2. (239 aa)
OFD1OFD1 centriole and centriolar satellite protein. (1013 aa)
TUBTubby-like protein; Belongs to the TUB family. (562 aa)
PSME4Proteasome activator subunit 4. (1792 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
ENSCATP00000040310ANK_REP_REGION domain-containing protein. (159 aa)
NUMBLNUMB like endocytic adaptor protein. (608 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (379 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSCATP00000037470AAA domain-containing protein. (389 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
FOPNLFGFR1OP N-terminal like. (204 aa)
THAP6THAP domain containing 6. (222 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
ENSCATP00000035052Uncharacterized protein. (211 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
ENSCATP00000034742JAB_MPN domain-containing protein. (166 aa)
GLIS1GLIS family zinc finger 1. (758 aa)
ENSCATP00000034003Uncharacterized protein. (124 aa)
ENSCATP00000033713LisH domain-containing protein. (198 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (526 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (585 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
IFT57Intraflagellar transport 57. (429 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (443 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
PSMB2Proteasome subunit beta. (201 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (24%) [HD]