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LOC105597100 LOC105597100 PRKAB2 PRKAB2 DESI1 DESI1 LOC105588042 LOC105588042 LOC105595720 LOC105595720 ENSCATP00000001318 ENSCATP00000001318 ENSCATP00000001452 ENSCATP00000001452 SFN SFN C1orf198 C1orf198 G6PD G6PD GPI GPI ENSCATP00000002799 ENSCATP00000002799 ENSCATP00000003364 ENSCATP00000003364 COX6B1 COX6B1 LRPPRC LRPPRC LOC105600051 LOC105600051 RRAGA RRAGA ENSCATP00000004823 ENSCATP00000004823 CRYGN CRYGN SESN2 SESN2 RRAGD RRAGD ENSCATP00000005647 ENSCATP00000005647 ENSCATP00000005714 ENSCATP00000005714 ENSCATP00000006157 ENSCATP00000006157 TACO1 TACO1 LOC105574517 LOC105574517 LOC105588083 LOC105588083 AKT1 AKT1 LOC105589984 LOC105589984 RPTOR RPTOR RRAGB RRAGB YWHAQ YWHAQ YWHAZ YWHAZ TXNDC11 TXNDC11 SESN1 SESN1 RRM2B RRM2B TXNDC2 TXNDC2 TNRC6B TNRC6B PRKAB1 PRKAB1 ENSCATP00000010748 ENSCATP00000010748 LAMTOR4 LAMTOR4 AGO3 AGO3 GSR GSR MLST8 MLST8 LAMTOR2 LAMTOR2 NDUFA4 NDUFA4 ENSCATP00000012820 ENSCATP00000012820 PRDX2 PRDX2 PTEN PTEN ENSCATP00000014833 ENSCATP00000014833 AGO1 AGO1 LOC105594544 LOC105594544 COX6A1 COX6A1 ENSCATP00000016555 ENSCATP00000016555 SLC38A9 SLC38A9 TSC1 TSC1 NME8 NME8 TIGAR TIGAR COX8A COX8A TXNDC8 TXNDC8 AKT3 AKT3 ENSCATP00000019939 ENSCATP00000019939 LOC105574720 LOC105574720 TXN TXN COX7B COX7B TXNRD1 TXNRD1 LAMTOR5 LAMTOR5 GLS GLS PRKAG1 PRKAG1 ENSCATP00000023795 ENSCATP00000023795 H6PD H6PD SCO1 SCO1 ENSCATP00000024481 ENSCATP00000024481 TP63 TP63 ENSCATP00000025219 ENSCATP00000025219 ENSCATP00000025523 ENSCATP00000025523 RRAGC RRAGC PRDX5 PRDX5 COX6A2 COX6A2 LOC105571774 LOC105571774 ENSCATP00000026342 ENSCATP00000026342 MOV10 MOV10 RHEB RHEB COX20 COX20 NME9 NME9 ENSCATP00000027912 ENSCATP00000027912 ENSCATP00000028110 ENSCATP00000028110 LAMTOR3 LAMTOR3 TSC2 TSC2 RHEBL1 RHEBL1 COX4I2 COX4I2 COX7A1 COX7A1 GATC GATC YWHAG YWHAG AGO2 AGO2 TP53 TP53 AKT2 AKT2 ENSCATP00000032552 ENSCATP00000032552 DESI2 DESI2 GLS2 GLS2 TXNRD3 TXNRD3 SESN3 SESN3 PRKAA1 PRKAA1 ENSCATP00000034811 ENSCATP00000034811 ENSCATP00000034901 ENSCATP00000034901 COX11 COX11 MTOR MTOR ENSCATP00000035839 ENSCATP00000035839 ENSCATP00000036022 ENSCATP00000036022 COX6B2 COX6B2 PRKAA2 PRKAA2 YWHAB YWHAB TRIR TRIR ENSCATP00000037030 ENSCATP00000037030 COX6C COX6C ENSCATP00000037714 ENSCATP00000037714 ENSCATP00000037760 ENSCATP00000037760 CRYBB3 CRYBB3 NPVF NPVF ENSCATP00000038840 ENSCATP00000038840 LOC105583702 LOC105583702 PRKAG2 PRKAG2 COX7B2 COX7B2 YWHAE YWHAE YWHAH YWHAH PRDX1 PRDX1 PRKAG3 PRKAG3 ENSCATP00000040576 ENSCATP00000040576 SURF1 SURF1 NDUFA4L2 NDUFA4L2 ENSCATP00000040781 ENSCATP00000040781 LOC105571593 LOC105571593 ENSCATP00000041144 ENSCATP00000041144 ENSCATP00000041282 ENSCATP00000041282 AGO4 AGO4 ENSCATP00000041581 ENSCATP00000041581 GPX2 GPX2 ENSCATP00000042086 ENSCATP00000042086 KIAA1671 KIAA1671 DDIT4L DDIT4L DDIT4 DDIT4 COX18 COX18 COX16 COX16 ENSCATP00000045721 ENSCATP00000045721 LAMTOR1 LAMTOR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105597100Uncharacterized protein. (114 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
DESI1Desumoylating isopeptidase 1. (168 aa)
LOC105588042Uncharacterized protein. (115 aa)
LOC105595720Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCATP00000001318Uncharacterized protein. (63 aa)
ENSCATP00000001452Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (98 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
C1orf198Chromosome 1 open reading frame 198. (327 aa)
G6PDGlucose-6-phosphate dehydrogenase. (543 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa)
ENSCATP00000002799Thioredoxin; Belongs to the thioredoxin family. (101 aa)
ENSCATP0000000336414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (87 aa)
LRPPRCPPR_long domain-containing protein. (1461 aa)
LOC105600051Uncharacterized protein. (157 aa)
RRAGARas related GTP binding A. (313 aa)
ENSCATP00000004823Uncharacterized protein. (91 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (182 aa)
SESN2Sestrin 2. (480 aa)
RRAGDRas related GTP binding D. (400 aa)
ENSCATP00000005647Uncharacterized protein. (63 aa)
ENSCATP00000005714Uncharacterized protein. (109 aa)
ENSCATP00000006157Uncharacterized protein. (63 aa)
TACO1Translational activator of cytochrome c oxidase I. (297 aa)
LOC105574517Uncharacterized protein. (169 aa)
LOC105588083Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC105589984Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1314 aa)
RRAGBRas related GTP binding B. (383 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
TXNDC11Thioredoxin domain containing 11. (986 aa)
SESN1Sestrin 1. (551 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (352 aa)
TXNDC2Thioredoxin domain-containing protein. (367 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1823 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
ENSCATP00000010748Thioredoxin domain-containing protein. (193 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
GSRGlutathione-disulfide reductase. (444 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (135 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (81 aa)
ENSCATP0000001282014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa)
PRDX2Peroxiredoxin 2. (198 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ENSCATP00000014833Uncharacterized protein. (106 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC105594544Uncharacterized protein. (169 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
ENSCATP00000016555Uncharacterized protein. (72 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
TSC1TSC complex subunit 1. (1167 aa)
NME8NME/NM23 family member 8. (588 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSCATP00000019939Cytochrome c oxidase subunit 6A, mitochondrial. (98 aa)
LOC105574720Uncharacterized protein. (63 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
TXNRD1Thioredoxin reductase 1. (648 aa)
LAMTOR5Uncharacterized protein. (125 aa)
GLSGlutaminase. (669 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa)
ENSCATP0000002379514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (238 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (883 aa)
SCO1SCO cytochrome c oxidase assembly protein 1. (303 aa)
ENSCATP00000024481Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
ENSCATP00000025219Thioredoxin domain-containing protein. (94 aa)
ENSCATP00000025523Uncharacterized protein. (91 aa)
RRAGCRas related GTP binding C. (399 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (215 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
LOC105571774CHCH domain-containing protein. (90 aa)
ENSCATP00000026342Uncharacterized protein. (138 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
RHEBRas homolog, mTORC1 binding. (196 aa)
COX20Cytochrome c oxidase assembly factor COX20. (130 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
ENSCATP00000027912Uncharacterized protein. (90 aa)
ENSCATP00000028110Thioredoxin domain-containing protein. (179 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
TSC2TSC complex subunit 2. (1807 aa)
RHEBL1RHEB like 1. (187 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (171 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (79 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (136 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (859 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSCATP00000032552Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (109 aa)
DESI2Desumoylating isopeptidase 2. (194 aa)
GLS2Glutaminase 2. (602 aa)
TXNRD3Thioredoxin reductase 3. (611 aa)
SESN3Sestrin 3. (530 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENSCATP00000034811Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
ENSCATP00000034901Uncharacterized protein. (125 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (276 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ENSCATP00000035839Uncharacterized protein. (74 aa)
ENSCATP00000036022Thioredoxin; Belongs to the thioredoxin family. (106 aa)
COX6B2Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
TRIRTelomerase RNA component interacting RNase. (176 aa)
ENSCATP00000037030Uncharacterized protein. (117 aa)
COX6CCytochrome c oxidase subunit 6C. (75 aa)
ENSCATP0000003771414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (232 aa)
ENSCATP00000037760Uncharacterized protein. (137 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
NPVFNeuropeptide VF precursor. (196 aa)
ENSCATP000000388401-cysPrx_C domain-containing protein. (94 aa)
LOC105583702Uncharacterized protein. (129 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
PRDX1Peroxiredoxin 1. (199 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ENSCATP0000004057614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa)
SURF1SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (300 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (94 aa)
ENSCATP00000040781annotation not available (63 aa)
LOC105571593Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCATP00000041144annotation not available (63 aa)
ENSCATP00000041282Uncharacterized protein. (79 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
ENSCATP00000041581Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
ENSCATP00000042086Uncharacterized protein. (116 aa)
KIAA1671KIAA1671. (1802 aa)
DDIT4LDNA damage inducible transcript 4 like. (193 aa)
DDIT4DNA damage inducible transcript 4. (233 aa)
COX18Cytochrome c oxidase assembly factor COX18. (333 aa)
COX16Uncharacterized protein. (106 aa)
ENSCATP00000045721Uncharacterized protein. (138 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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