Your Input: | |
| | MAPKAPK5 | MAPK activated protein kinase 5. (474 aa) |
| | ENSCATP00000000090 | Uncharacterized protein. (233 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (994 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (241 aa) |
| | RNF34 | Ring finger protein 34. (377 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (905 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa) |
| | EXO1 | Exonuclease 1. (846 aa) |
| | ENSCATP00000001548 | Protein kinase domain-containing protein. (250 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa) |
| | HUS1B | Checkpoint protein; Belongs to the HUS1 family. (277 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | CHD4 | Uncharacterized protein. (1912 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1205 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (738 aa) |
| | RFC5 | Replication factor C subunit 5. (343 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (516 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | RMI2 | RecQ mediated genome instability 2. (147 aa) |
| | LOC105576738 | Ubiquitin-like domain-containing protein. (134 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | ENSCATP00000006421 | Protein kinase domain-containing protein. (297 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | CHEK1 | Checkpoint kinase 1. (493 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | BRD9 | Bromodomain containing 9. (597 aa) |
| | LOC105579396 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSCATP00000007311 | Uncharacterized protein. (297 aa) |
| | LOC105595668 | Ubiquitin-like domain-containing protein. (126 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (593 aa) |
| | TAF9B | Uncharacterized protein. (251 aa) |
| | ZNF385B | Zinc finger protein 385B. (471 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (986 aa) |
| | FOXP4 | Forkhead box P4. (680 aa) |
| | C17orf113 | Chromosome 17 open reading frame 113. (675 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | BRD7 | Bromodomain containing 7. (652 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | PRDM1 | PR/SET domain 1. (825 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | ENSCATP00000011714 | Uncharacterized protein. (288 aa) |
| | RFC4 | Replication factor C subunit 4. (349 aa) |
| | ENSCATP00000011808 | Ubiquitin-like domain-containing protein. (130 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | ENSCATP00000012198 | TAFII28 domain-containing protein. (196 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (335 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (620 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (931 aa) |
| | PHF20 | PHD finger protein 20. (1012 aa) |
| | RECQL4 | RecQ like helicase 4. (1208 aa) |
| | USP7 | Uncharacterized protein; Belongs to the peptidase C19 family. (1093 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | PRR5 | Proline rich 5. (410 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (990 aa) |
| | PLK5 | Polo like kinase 5. (336 aa) |
| | BANP | BTG3 associated nuclear protein. (538 aa) |
| | ENSCATP00000016162 | TAFII28 domain-containing protein. (167 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PWWP2A | PWWP domain containing 2A. (755 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (534 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (862 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (440 aa) |
| | AURKA | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa) |
| | LOC105576377 | Uncharacterized protein. (261 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (747 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ENSCATP00000020093 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (433 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1056 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | AIRE | Autoimmune regulator. (549 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (720 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (828 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa) |
| | ATRIP | ATR interacting protein. (711 aa) |
| | CHEK2 | Checkpoint kinase 2. (589 aa) |
| | GATAD2A | GATA-type domain-containing protein. (642 aa) |
| | ZNF385A | Zinc finger protein 385A. (414 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | SETD9 | SET domain containing 9. (270 aa) |
| | L3MBTL4 | L3MBTL histone methyl-lysine binding protein 4. (623 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | ENSCATP00000039365 | WD_REPEATS_REGION domain-containing protein. (253 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | L3MBTL1 | Uncharacterized protein. (839 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | BRPF1 | Uncharacterized protein. (1253 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (280 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1934 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (777 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1298 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | SMYD2 | SET and MYND domain containing 2. (426 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1090 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa) |
| | ENSCATP00000042480 | Uncharacterized protein. (159 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (213 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | NUAK2 | NUAK family kinase 2. (672 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (291 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (529 aa) |
| | ENSCATP00000043644 | Ubiquitin-like domain-containing protein. (120 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1266 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (994 aa) |
| | KMT5A | Lysine methyltransferase 5A. (360 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (424 aa) |
| | ING1 | Inhibitor of growth protein. (397 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa) |
| | ZNF385C | Zinc finger protein 385C. (500 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (592 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1059 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1134 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1215 aa) |
| | BRD1 | Bromodomain containing 1. (1119 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | ENSCATP00000030465 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (199 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | ENSCATP00000031033 | Ubiquitin-like domain-containing protein. (149 aa) |
| | TBP | TATA-box binding protein. (327 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (643 aa) |
| | ENSCATP00000031804 | WD_REPEATS_REGION domain-containing protein. (361 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | LOC105575995 | WD_REPEATS_REGION domain-containing protein. (430 aa) |
| | LOC105573813 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3073 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | ING5 | Inhibitor of growth family member 5. (253 aa) |
| | ENSCATP00000033461 | P66_CC domain-containing protein. (162 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | ENSCATP00000034029 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (581 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | NUAK1 | NUAK family kinase 1. (667 aa) |
| | ENSCATP00000034768 | Ubiquitin-like domain-containing protein. (144 aa) |
| | LOC105594398 | TATA-box binding protein associated factor 13. (92 aa) |
| | ENSCATP00000035073 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (451 aa) |
| | ENSCATP00000035134 | Ubiquitin-like domain-containing protein. (146 aa) |
| | CSNK2B | Uncharacterized protein. (298 aa) |
| | WRN | WRN RecQ like helicase. (1418 aa) |
| | BLM | BLM RecQ like helicase. (1416 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | LOC105599742 | Zinc-hook domain-containing protein. (1192 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (211 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1199 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | DAXX | Death domain associated protein. (739 aa) |
| | ENSCATP00000027160 | Uncharacterized protein. (232 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (668 aa) |
| | ENSCATP00000027386 | Uncharacterized protein. (109 aa) |
| | MEAF6 | Uncharacterized protein. (201 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (464 aa) |
| | ENSCATP00000027778 | WD_REPEATS_REGION domain-containing protein. (356 aa) |
| | POU4F1 | POU domain protein. (389 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (369 aa) |
| | LOC105594328 | Uncharacterized protein. (86 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (340 aa) |
| | LOC105573488 | WD_REPEATS_REGION domain-containing protein. (371 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | ENSCATP00000036401 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (262 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (673 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2059 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1217 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ENSCATP00000039008 | Uncharacterized protein. (112 aa) |
| | TP53RK | TP53 regulating kinase. (253 aa) |
