STRINGSTRING
LOC105595668 LOC105595668 ENSCATP00000007407 ENSCATP00000007407 HRAS HRAS MAPK1 MAPK1 FGF16 FGF16 KRAS KRAS MAPK3 MAPK3 FGF9 FGF9 KLB KLB ERAS ERAS CSDE1 CSDE1 FRS2 FRS2 PIK3R1 PIK3R1 FGFR4 FGFR4 ENSCATP00000030673 ENSCATP00000030673 FGF19 FGF19 ENSCATP00000031033 ENSCATP00000031033 FGF23 FGF23 FRS3 FRS3 PPP2CA PPP2CA PPP2R1A PPP2R1A ENSCATP00000034768 ENSCATP00000034768 ENSCATP00000035134 ENSCATP00000035134 FGF18 FGF18 NRAS NRAS MKNK1 MKNK1 MKNK2 MKNK2 RPS27A RPS27A GRB2 GRB2 FNDC3A FNDC3A ENSCATP00000043644 ENSCATP00000043644 ENSCATP00000044421 ENSCATP00000044421 FGF17 FGF17 SHC1 SHC1 PIK3CA PIK3CA FGF6 FGF6 LOC105585293 LOC105585293 PLCG1 PLCG1 FGF4 FGF4 BRAF BRAF SPRY2 SPRY2 FNDC3B FNDC3B ENSCATP00000005869 ENSCATP00000005869 GAB1 GAB1 CBL CBL FGF2 FGF2 FGF20 FGF20 PPP2CB PPP2CB SOS1 SOS1 SRC SRC PTPN11 PTPN11 FGF1 FGF1 UBA52 UBA52 FGF8 FGF8 LOC105576738 LOC105576738 LOC105579396 LOC105579396
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105595668Ubiquitin-like domain-containing protein. (126 aa)
ENSCATP00000007407PID domain-containing protein. (502 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KLBKlotho beta. (1044 aa)
ERASES cell expressed Ras. (233 aa)
CSDE1Cold shock domain containing E1. (844 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
ENSCATP00000030673Uncharacterized protein. (652 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (476 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSCATP00000043644Ubiquitin-like domain-containing protein. (120 aa)
ENSCATP00000044421Uncharacterized protein. (441 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
SHC1SHC adaptor protein 1. (584 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC105585293Uncharacterized protein. (290 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (762 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
FNDC3BFibronectin type III domain containing 3B. (1158 aa)
ENSCATP00000005869Uncharacterized protein. (526 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
CBLCbl proto-oncogene. (907 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SRCTyrosine-protein kinase. (644 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (552 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LOC105576738Ubiquitin-like domain-containing protein. (134 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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