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ENSCATP00000000811 ENSCATP00000000811 ACTG1 ACTG1 LOC105571986 LOC105571986 ENSCATP00000004469 ENSCATP00000004469 ENSCATP00000005099 ENSCATP00000005099 PTK2 PTK2 ACTRT1 ACTRT1 WASHC1 WASHC1 NCKIPSD NCKIPSD FMN1 FMN1 ENSCATP00000006802 ENSCATP00000006802 ACTL7A ACTL7A NCKAP1 NCKAP1 ACTL7B ACTL7B WIPF1 WIPF1 WASF2 WASF2 ENSCATP00000009637 ENSCATP00000009637 WASF1 WASF1 MAPK3 MAPK3 NCK1 NCK1 ENSCATP00000013162 ENSCATP00000013162 ACTB ACTB BRK1 BRK1 MAPK1 MAPK1 ENSCATP00000017084 ENSCATP00000017084 ABL1 ABL1 ARPC2 ARPC2 ENSCATP00000019657 ENSCATP00000019657 ENSCATP00000019774 ENSCATP00000019774 BTK BTK ACTR3 ACTR3 ARPC1A ARPC1A CDC42 CDC42 ARPC4 ARPC4 ACTL8 ACTL8 ACTR2 ACTR2 ARPC1B ARPC1B ENSCATP00000027915 ENSCATP00000027915 ARPC5L ARPC5L CYFIP2 CYFIP2 WASF3 WASF3 ARPC5 ARPC5 ENSCATP00000029599 ENSCATP00000029599 ABI2 ABI2 WIPF2 WIPF2 NCKAP1L NCKAP1L WASL WASL LOC105579900 LOC105579900 ARPC3 ARPC3 WIPF3 WIPF3 CYFIP1 CYFIP1 BAIAP2 BAIAP2 ENSCATP00000039367 ENSCATP00000039367 LOC105573641 LOC105573641 ACTR3B ACTR3B GRB2 GRB2 ENSCATP00000042801 ENSCATP00000042801 ENSCATP00000043705 ENSCATP00000043705 WAS WAS ABI1 ABI1 FMN2 FMN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000000811Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (337 aa)
ACTG1Actin gamma 1. (377 aa)
LOC105571986Uncharacterized protein. (189 aa)
ENSCATP00000004469Uncharacterized protein. (191 aa)
ENSCATP00000005099Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (161 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1068 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
WASHC1WASH complex subunit 1. (473 aa)
NCKIPSDNCK interacting protein with SH3 domain. (719 aa)
FMN1Formin 1. (1425 aa)
ENSCATP00000006802Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
NCKAP1NCK associated protein 1. (1134 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
WIPF1WAS/WASL interacting protein family member 1. (510 aa)
WASF2WASP family member 2. (498 aa)
ENSCATP00000009637Uncharacterized protein. (61 aa)
WASF1WASP family member 1. (559 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
NCK1Cytoplasmic protein. (377 aa)
ENSCATP00000013162Uncharacterized protein. (173 aa)
ACTBUncharacterized protein. (375 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSCATP00000017084Uncharacterized protein. (185 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
ENSCATP00000019657Uncharacterized protein; Belongs to the actin family. (368 aa)
ENSCATP00000019774Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (139 aa)
BTKTyrosine-protein kinase. (659 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
CDC42Uncharacterized protein. (191 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (290 aa)
ACTL8Actin like 8; Belongs to the actin family. (386 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
ENSCATP00000027915Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (143 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
WASF3WASP family member 3. (502 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSCATP00000029599WD_REPEATS_REGION domain-containing protein. (334 aa)
ABI2Abl interactor 2. (513 aa)
WIPF2WAS/WASL interacting protein family member 2. (440 aa)
NCKAP1LNCK associated protein 1 like. (1060 aa)
WASLWASP like actin nucleation promoting factor. (503 aa)
LOC105579900Uncharacterized protein. (319 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (182 aa)
WIPF3WAS/WASL interacting protein family member 3. (486 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1239 aa)
BAIAP2BAI1 associated protein 2. (561 aa)
ENSCATP00000039367Uncharacterized protein. (360 aa)
LOC105573641Uncharacterized protein; Belongs to the actin family. (323 aa)
ACTR3BActin related protein 3B; Belongs to the actin family. (418 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSCATP00000042801Uncharacterized protein. (136 aa)
ENSCATP00000043705Uncharacterized protein. (238 aa)
WASWASP actin nucleation promoting factor. (503 aa)
ABI1Abl interactor 1. (508 aa)
FMN2Formin 2. (1435 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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