STRINGSTRING
PSMD5 PSMD5 UBE2S UBE2S CDT1 CDT1 GMNN GMNN GINS1 GINS1 ANAPC4 ANAPC4 PSMB1 PSMB1 RBX1 RBX1 ENSCATP00000025966 ENSCATP00000025966 ENSCATP00000026110 ENSCATP00000026110 CCNE1 CCNE1 MCM8 MCM8 PSMD2 PSMD2 PSMD1 PSMD1 PSMD8 PSMD8 PSMA6 PSMA6 PSMC1 PSMC1 ENSCATP00000031033 ENSCATP00000031033 FAM89B FAM89B PSMB2 PSMB2 ANAPC10 ANAPC10 ANAPC5 ANAPC5 MCM7 MCM7 CCNA1 CCNA1 PSMB4 PSMB4 PSMA3 PSMA3 POLA1 POLA1 TM4SF19 TM4SF19 PSMC2 PSMC2 PSMA8 PSMA8 MCM9 MCM9 CDC27 CDC27 ANAPC2 ANAPC2 ENSCATP00000034742 ENSCATP00000034742 ENSCATP00000034768 ENSCATP00000034768 ENSCATP00000035052 ENSCATP00000035052 ENSCATP00000035134 ENSCATP00000035134 POLD2 POLD2 CDK3 CDK3 ENSCATP00000036401 ENSCATP00000036401 CUL1 CUL1 PSMD3 PSMD3 GINS3 GINS3 ENSCATP00000037470 ENSCATP00000037470 PSMB6 PSMB6 PSMA4 PSMA4 PSMB9 PSMB9 SKP1 SKP1 PSMD13 PSMD13 ORC6 ORC6 GINS4 GINS4 ENSCATP00000000117 ENSCATP00000000117 UBE2D1 UBE2D1 FEN1 FEN1 POLE POLE PSMB11 PSMB11 ENSCATP00000002953 ENSCATP00000002953 PSMA7 PSMA7 RFC3 RFC3 RFC5 RFC5 ENSCATP00000003644 ENSCATP00000003644 MEIOB MEIOB ENSCATP00000003690 ENSCATP00000003690 PSMA1 PSMA1 RFC1 RFC1 PSMF1 PSMF1 ENSCATP00000004934 ENSCATP00000004934 CDC26 CDC26 POLA2 POLA2 ORC2 ORC2 LOC105576738 LOC105576738 PSMC3 PSMC3 LOC105579396 LOC105579396 ANAPC11 ANAPC11 LOC105595668 LOC105595668 PSMD7 PSMD7 PSMB8 PSMB8 RPA3 RPA3 ANAPC1 ANAPC1 CDC23 CDC23 MCM6 MCM6 CCNA2 CCNA2 ENSCATP00000010534 ENSCATP00000010534 MCM2 MCM2 PSMC4 PSMC4 PSMD14 PSMD14 RCBTB1 RCBTB1 LIG1 LIG1 ORC1 ORC1 ENSCATP00000040310 ENSCATP00000040310 ENSCATP00000040523 ENSCATP00000040523 CDK2 CDK2 ORC3 ORC3 ENSCATP00000041490 ENSCATP00000041490 POLD3 POLD3 POLE3 POLE3 RPS27A RPS27A ANAPC15 ANAPC15 PSME3 PSME3 PSMD11 PSMD11 GINS2 GINS2 ENSCATP00000042421 ENSCATP00000042421 MCM5 MCM5 ENSCATP00000042752 ENSCATP00000042752 CDC16 CDC16 PSMB5 PSMB5 ENSCATP00000020357 ENSCATP00000020357 PSMB7 PSMB7 ENSCATP00000020004 ENSCATP00000020004 RCBTB2 RCBTB2 POLE4 POLE4 PSMD10 PSMD10 PSMA5 PSMA5 POLE2 POLE2 PSMD12 PSMD12 PSMB10 PSMB10 UBE2E1 UBE2E1 LOC105579883 LOC105579883 CDC45 CDC45 UBA52 UBA52 FAM89A FAM89A ENSCATP00000016481 ENSCATP00000016481 ORC5 ORC5 ENSCATP00000016334 ENSCATP00000016334 ANAPC7 ANAPC7 ENSCATP00000015253 ENSCATP00000015253 PSMB3 PSMB3 MCM3 MCM3 MCM4 MCM4 POLD4 POLD4 TM7SF3 TM7SF3 PSMD9 PSMD9 PSME1 PSME1 ENSCATP00000021172 ENSCATP00000021172 SKP2 SKP2 ENSCATP00000020493 ENSCATP00000020493 PRIM1 PRIM1 PSMC5 PSMC5 DNA2 DNA2 ENSCATP00000014541 ENSCATP00000014541 PSMC6 PSMC6 CDC6 CDC6 PSMD4 PSMD4 UBE2C UBE2C PCNA PCNA RFC2 RFC2 PSMD6 PSMD6 ANAPC16 ANAPC16 ENSCATP00000011971 ENSCATP00000011971 ENSCATP00000011808 ENSCATP00000011808 RFC4 RFC4 ENSCATP00000011745 ENSCATP00000011745 POLD1 POLD1 ENSCATP00000011080 ENSCATP00000011080 ENSCATP00000010732 ENSCATP00000010732 PSMA2 PSMA2 CCNE2 CCNE2 ORC4 ORC4 PSME4 PSME4 FZR1 FZR1 PSME2 PSME2 ATAD5 ATAD5 ENSCATP00000043644 ENSCATP00000043644
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD5Proteasome 26S subunit, non-ATPase 5. (508 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
CDT1Chromatin licensing and DNA replication factor 1. (545 aa)
GMNNGeminin DNA replication inhibitor. (211 aa)
GINS1GINS complex subunit 1. (196 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa)
PSMB1Proteasome subunit beta. (241 aa)
RBX1Ring-box 1. (108 aa)
ENSCATP00000025966DOC domain-containing protein. (128 aa)
ENSCATP00000026110Uncharacterized protein. (222 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (880 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
FAM89BFamily with sequence similarity 89 member B. (154 aa)
PSMB2Proteasome subunit beta. (201 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
ANAPC5Anaphase promoting complex subunit 5. (679 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
POLA1DNA polymerase. (1469 aa)
TM4SF19Uncharacterized protein. (209 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa)
CDC27Cell division cycle 27. (830 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
ENSCATP00000034742JAB_MPN domain-containing protein. (166 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
ENSCATP00000035052Uncharacterized protein. (211 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
ENSCATP00000036401Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (262 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
GINS3GINS complex subunit 3. (255 aa)
ENSCATP00000037470AAA domain-containing protein. (389 aa)
PSMB6Proteasome subunit beta. (285 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
PSMB9Proteasome subunit beta. (219 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (379 aa)
ORC6Origin recognition complex subunit 6. (229 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
ENSCATP00000000117Uncharacterized protein. (93 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
PSMB11Proteasome subunit beta. (300 aa)
ENSCATP00000002953Uncharacterized protein. (85 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
RFC3Replication factor C subunit 3. (356 aa)
RFC5Replication factor C subunit 5. (343 aa)
ENSCATP00000003644ANK_REP_REGION domain-containing protein. (116 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
ENSCATP00000003690UBIQUITIN_CONJUGAT_2 domain-containing protein. (157 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
RFC1Replication factor C subunit 1. (1113 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSCATP00000004934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
CDC26Cell division cycle 26. (85 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
ORC2Origin recognition complex subunit 2. (577 aa)
LOC105576738Ubiquitin-like domain-containing protein. (134 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
ANAPC11Anaphase promoting complex subunit 11. (180 aa)
LOC105595668Ubiquitin-like domain-containing protein. (126 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMB8Proteasome subunit beta. (276 aa)
RPA3Replication protein A3. (121 aa)
ANAPC1Anaphase promoting complex subunit 1. (1877 aa)
CDC23Cell division cycle 23. (597 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
ENSCATP00000010534Sld5 domain-containing protein. (165 aa)
MCM2DNA helicase; Belongs to the MCM family. (904 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
LIG1DNA ligase. (918 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
ENSCATP00000040310ANK_REP_REGION domain-containing protein. (159 aa)
ENSCATP00000040523UBIQUITIN_CONJUGAT_2 domain-containing protein. (179 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
ORC3Origin recognition complex subunit 3. (716 aa)
ENSCATP00000041490AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa)
POLD3Uncharacterized protein. (466 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ANAPC15Anaphase promoting complex subunit 15. (190 aa)
PSME3Proteasome activator subunit 3. (265 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
ENSCATP00000042421UBIQUITIN_CONJUGAT_2 domain-containing protein. (167 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
ENSCATP00000042752Uncharacterized protein. (79 aa)
CDC16Cell division cycle 16. (602 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSCATP00000020357AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSCATP00000020004Uncharacterized protein; Belongs to the SKP1 family. (198 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (556 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (117 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB10Proteasome subunit beta. (273 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
LOC105579883Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (238 aa)
CDC45Cell division cycle 45. (598 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FAM89AFamily with sequence similarity 89 member A. (184 aa)
ENSCATP00000016481AAA domain-containing protein. (370 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
ENSCATP00000016334Uncharacterized protein. (338 aa)
ANAPC7Anaphase promoting complex subunit 7. (559 aa)
ENSCATP00000015253AAA domain-containing protein. (373 aa)
PSMB3Proteasome subunit beta. (205 aa)
MCM3DNA helicase; Belongs to the MCM family. (853 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
POLD4Uncharacterized protein. (107 aa)
TM7SF3Transmembrane 7 superfamily member 3. (585 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSCATP00000021172Uncharacterized protein. (278 aa)
SKP2S-phase kinase associated protein 2. (437 aa)
ENSCATP00000020493Uncharacterized protein. (150 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
DNA2DNA replication helicase/nuclease 2. (1056 aa)
ENSCATP00000014541Prot_ATP_ID_OB domain-containing protein. (172 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (599 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (363 aa)
UBE2CUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (205 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RFC2Replication factor C subunit 2. (352 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
ENSCATP00000011971Uncharacterized protein. (191 aa)
ENSCATP00000011808Ubiquitin-like domain-containing protein. (130 aa)
RFC4Replication factor C subunit 4. (349 aa)
ENSCATP00000011745AAA domain-containing protein. (410 aa)
POLD1DNA polymerase. (1107 aa)
ENSCATP00000011080Uncharacterized protein. (77 aa)
ENSCATP00000010732CSN8_PSD8_EIF3K domain-containing protein. (249 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
ORC4Origin recognition complex subunit 4. (339 aa)
PSME4Proteasome activator subunit 4. (1792 aa)
FZR1Fizzy and cell division cycle 20 related 1. (587 aa)
PSME2Proteasome activator subunit 2. (239 aa)
ATAD5ATPase family AAA domain containing 5. (1832 aa)
ENSCATP00000043644Ubiquitin-like domain-containing protein. (120 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (24%) [HD]