node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBFB | CREBBP | ENSCATP00000040224 | ENSCATP00000033055 | Core-binding factor subunit beta. | CREB binding protein. | 0.608 |
CBFB | RUNX1 | ENSCATP00000040224 | ENSCATP00000035566 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.979 |
CBFB | RUNX2 | ENSCATP00000040224 | ENSCATP00000027316 | Core-binding factor subunit beta. | RUNX family transcription factor 2. | 0.973 |
CREBBP | CBFB | ENSCATP00000033055 | ENSCATP00000040224 | CREB binding protein. | Core-binding factor subunit beta. | 0.608 |
CREBBP | RUNX1 | ENSCATP00000033055 | ENSCATP00000035566 | CREB binding protein. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.731 |
CREBBP | RUNX2 | ENSCATP00000033055 | ENSCATP00000027316 | CREB binding protein. | RUNX family transcription factor 2. | 0.634 |
CSF2 | RUNX1 | ENSCATP00000039017 | ENSCATP00000035566 | Colony stimulating factor 2. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.901 |
CSF2 | RUNX2 | ENSCATP00000039017 | ENSCATP00000027316 | Colony stimulating factor 2. | RUNX family transcription factor 2. | 0.655 |
LGALS3 | RUNX1 | ENSCATP00000044540 | ENSCATP00000035566 | Galectin. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.453 |
LGALS3 | RUNX2 | ENSCATP00000044540 | ENSCATP00000027316 | Galectin. | RUNX family transcription factor 2. | 0.486 |
PRKCB | RUNX1 | ENSCATP00000008587 | ENSCATP00000035566 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.417 |
RUNX1 | CBFB | ENSCATP00000035566 | ENSCATP00000040224 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Core-binding factor subunit beta. | 0.979 |
RUNX1 | CREBBP | ENSCATP00000035566 | ENSCATP00000033055 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | CREB binding protein. | 0.731 |
RUNX1 | CSF2 | ENSCATP00000035566 | ENSCATP00000039017 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Colony stimulating factor 2. | 0.901 |
RUNX1 | LGALS3 | ENSCATP00000035566 | ENSCATP00000044540 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Galectin. | 0.453 |
RUNX1 | PRKCB | ENSCATP00000035566 | ENSCATP00000008587 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.417 |
RUNX1 | RUNX2 | ENSCATP00000035566 | ENSCATP00000027316 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | RUNX family transcription factor 2. | 0.504 |
RUNX2 | CBFB | ENSCATP00000027316 | ENSCATP00000040224 | RUNX family transcription factor 2. | Core-binding factor subunit beta. | 0.973 |
RUNX2 | CREBBP | ENSCATP00000027316 | ENSCATP00000033055 | RUNX family transcription factor 2. | CREB binding protein. | 0.634 |
RUNX2 | CSF2 | ENSCATP00000027316 | ENSCATP00000039017 | RUNX family transcription factor 2. | Colony stimulating factor 2. | 0.655 |