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| | HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (405 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (511 aa) |
| | SLC51A | Solute carrier family 51 alpha subunit. (340 aa) |
| | EBP | EXPERA domain-containing protein. (230 aa) |
| | GC | GC vitamin D binding protein. (474 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa) |
| | HSD17B3 | Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa) |
| | ENSCATP00000023108 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (338 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (418 aa) |
| | CARM1 | Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (661 aa) |
| | ENSCATP00000021602 | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (308 aa) |
| | TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (514 aa) |
| | SCD | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | RXRA | Retinoid X receptor alpha. (630 aa) |
| | EBPL | Uncharacterized protein. (102 aa) |
| | IDI1 | Isopentenyl-diphosphate delta isomerase 1. (280 aa) |
| | STARD3 | StAR related lipid transfer domain containing 3. (488 aa) |
| | ENSCATP00000019902 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (356 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) |
| | SQLE | Squalene epoxidase. (574 aa) |
| | NFYC | Nuclear transcription factor Y subunit gamma. (439 aa) |
| | SEC24B | SEC24 homolog B, COPII coat complex component. (1261 aa) |
| | ENSCATP00000017225 | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (364 aa) |
| | NFYA | Nuclear transcription factor Y subunit alpha. (347 aa) |
| | ENSCATP00000016881 | START domain-containing protein. (247 aa) |
| | STARD5 | StAR related lipid transfer domain containing 5. (213 aa) |
| | MVD | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (401 aa) |
| | HSD17B2 | Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (263 aa) |
| | HSD3B2 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2. (422 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1570 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (500 aa) |
| | MBTPS2 | Membrane bound transcription factor peptidase, site 2. (520 aa) |
| | STARD6 | StAR related lipid transfer domain containing 6. (220 aa) |
| | LOC105598240 | Uncharacterized protein. (1639 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (205 aa) |
| | FADS6 | Fatty acid desaturase 6. (218 aa) |
| | LBR | Lamin B receptor. (615 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (575 aa) |
| | CYP21A2 | Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (399 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | ENSCATP00000013903 | Aldo_ket_red domain-containing protein. (269 aa) |
| | ENSCATP00000013840 | Aldo_ket_red domain-containing protein. (256 aa) |
| | HSD17B7 | Hydroxysteroid 17-beta dehydrogenase 7. (359 aa) |
| | HSD17B4 | Hydroxysteroid 17-beta dehydrogenase 4. (757 aa) |
| | ENSCATP00000012742 | Aldo_ket_red domain-containing protein. (272 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1317 aa) |
| | HSD17B14 | Hydroxysteroid 17-beta dehydrogenase 14. (270 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2389 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (620 aa) |
| | ALB | Albumin. (608 aa) |
| | MTF1 | Metal regulatory transcription factor 1. (656 aa) |
| | ENSCATP00000029205 | Rad60-SLD domain-containing protein. (74 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa) |
| | FASN | Fatty acid synthase. (2511 aa) |
| | TSPO2 | Translocator protein 2. (170 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2458 aa) |
| | AKR1E2 | Aldo-keto reductase family 1 member E2. (355 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (515 aa) |
| | ENSCATP00000030652 | Ubiquitin-like domain-containing protein. (136 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (732 aa) |
| | ENSCATP00000030199 | Aldo_ket_red domain-containing protein. (253 aa) |
| | SEC23A | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa) |
| | NSDHL | NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2885 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1146 aa) |
| | STARD3NL | MENTAL domain-containing protein. (234 aa) |
| | AKR1B1 | Aldo-keto reductase family 1 member B. (316 aa) |
| | RIMBP2 | RIMS binding protein 2. (1052 aa) |
| | KPNB1 | Karyopherin subunit beta 1. (876 aa) |
| | SEC24C | SEC24 homolog C, COPII coat complex component. (1094 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (237 aa) |
| | ACOX2 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa) |
| | AKR1C8P | Aldo-keto reductase family 1 member C8, pseudogene. (325 aa) |
| | AMACR | Alpha-methylacyl-CoA racemase. (382 aa) |
| | SLC10A2 | Solute carrier family 10 member 2. (348 aa) |
| | TSPOAP1 | TSPO associated protein 1. (1874 aa) |
| | FDXR | NADPH:adrenodoxin oxidoreductase, mitochondrial. (521 aa) |
| | ABCC3 | ABC transmembrane type-1 domain-containing protein. (477 aa) |
| | CUBN | Cubilin. (3620 aa) |
| | FDX2 | 2Fe-2S ferredoxin-type domain-containing protein. (186 aa) |
| | NCOA6 | Nuclear receptor coactivator 6. (2068 aa) |
| | SLC10A1 | Solute carrier family 10 member 1. (349 aa) |
| | SERPINA6 | Serpin family A member 6; Belongs to the serpin family. (404 aa) |
| | SCAP | SREBF chaperone. (1261 aa) |
| | OSBPL3 | Oxysterol-binding protein; Belongs to the OSBP family. (887 aa) |
| | SLC51B | Solute carrier family 51 beta subunit. (231 aa) |
| | PMVK | Phosphomevalonate kinase. (192 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa) |
| | ENSCATP00000040646 | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (330 aa) |
| | HSD11B1 | Hydroxysteroid 11-beta dehydrogenase 1. (292 aa) |
| | LGMN | Legumain. (433 aa) |
| | OSBP2 | Oxysterol-binding protein; Belongs to the OSBP family. (916 aa) |
| | NFYB | CBFD_NFYB_HMF domain-containing protein. (208 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | ENSCATP00000039607 | CBFD_NFYB_HMF domain-containing protein. (280 aa) |
| | GGPS1 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (300 aa) |
| | FABP6 | Fatty acid binding protein 6. (154 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (482 aa) |
| | ENSCATP00000038979 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (352 aa) |
| | SC5D | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa) |
| | ENSCATP00000038483 | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (188 aa) |
| | HSDL2 | Hydroxysteroid dehydrogenase like 2. (418 aa) |
| | ENSCATP00000037976 | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (321 aa) |
| | LOC105597444 | Aldo_ket_red domain-containing protein. (267 aa) |
| | ENSCATP00000037772 | Thiolase_N domain-containing protein. (276 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1177 aa) |
| | ENSCATP00000037326 | Uncharacterized protein. (270 aa) |
| | CYP17A1 | Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa) |
| | SDR42E1 | Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (393 aa) |
| | LRP2 | LDL receptor related protein 2. (4655 aa) |
| | POMC | Proopiomelanocortin. (265 aa) |
| | RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (234 aa) |
| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (419 aa) |
| | HSD17B11 | Hydroxysteroid 17-beta dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (959 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (238 aa) |
| | ENSCATP00000034372 | MENTAL domain-containing protein. (209 aa) |
| | SRD5A3 | Steroid 5 alpha-reductase 3. (318 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | OSBPL9 | Oxysterol-binding protein; Belongs to the OSBP family. (746 aa) |
| | ACOT8 | Acyl-CoA thioesterase 8. (319 aa) |
| | CDCP2 | CUB domain containing protein 2. (540 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | CYP2R1 | Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (533 aa) |
| | ENSCATP00000032866 | Uncharacterized protein. (66 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (949 aa) |
| | SEC24A | SEC24 homolog A, COPII coat complex component. (1078 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (391 aa) |
| | SLCO1A2 | Solute carrier organic anion transporter family member. (670 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (682 aa) |
| | LOC105597447 | Aldo_ket_red domain-containing protein. (323 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1468 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (815 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | ENSCATP00000032038 | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (403 aa) |
| | PLPP7 | Phospholipid phosphatase 7 (inactive). (271 aa) |
| | SAR1A | Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | HMGCS1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa) |
| | ENSCATP00000031520 | CBFD_NFYB_HMF domain-containing protein. (193 aa) |
| | SEC24D | SEC24 homolog D, COPII coat complex component. (1033 aa) |
| | ENSCATP00000031206 | Ubiquitin-like domain-containing protein. (128 aa) |
| | SLCO1B1 | Solute carrier organic anion transporter family member. (702 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | IDI2 | Isopentenyl-diphosphate delta isomerase 2. (136 aa) |
| | FDX1 | Ferredoxin 1. (172 aa) |
| | ACAT2 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | SRD5A2 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa) |
| | HSD17B1 | Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | ENSCATP00000010735 | Ubiquitin-like domain-containing protein. (132 aa) |
| | RUSC1 | RUN and SH3 domain containing 1. (1042 aa) |
| | MSMO1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (274 aa) |
| | VDR | Vitamin D receptor. (477 aa) |
| | HSD3B1 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa) |
| | FAXDC2 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (333 aa) |
| | SEC23B | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa) |
| | FDFT1 | Farnesyl-diphosphate farnesyltransferase 1. (417 aa) |
| | CYP19A1 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa) |
| | CYP51A1 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (509 aa) |
| | SAR1B | Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | PLPP6 | Phospholipid phosphatase 6. (296 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa) |
| | ADGRD1 | Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (908 aa) |
| | DHRS7C | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1052 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | LOC105581294 | Uncharacterized protein; Belongs to the cytochrome P450 family. (443 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) |
| | HELZ2 | Helicase with zinc finger 2. (2849 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | DHCR24 | 24-dehydrocholesterol reductase. (513 aa) |
| | LOC105587685 | Aldo-keto reductase family 1 member C1. (275 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (480 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | SLC27A5 | Solute carrier family 27 member 5. (690 aa) |
| | LOC105587688 | Aldo_ket_red domain-containing protein. (323 aa) |
| | TBL1X | Transducin beta like 1 X-linked. (573 aa) |
| | MVK | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (418 aa) |
| | ENSCATP00000002113 | Uncharacterized protein. (125 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | TM7SF2 | Transmembrane 7 superfamily member 2. (418 aa) |
| | CYP11B1 | Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. (573 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | TGS1 | Trimethylguanosine synthase 1. (855 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1515 aa) |
