STRINGSTRING
RBX1 RBX1 NCSTN NCSTN PSMD2 PSMD2 PSMD1 PSMD1 PSMD8 PSMD8 PSMA6 PSMA6 PSMC3 PSMC3 AKT1 AKT1 ENSCATP00000004934 ENSCATP00000004934 PSMF1 PSMF1 PSMA1 PSMA1 ENSCATP00000003644 ENSCATP00000003644 ENSCATP00000003364 ENSCATP00000003364 PSMA7 PSMA7 SMAD3 SMAD3 HEY1 HEY1 ENSCATP00000000117 ENSCATP00000000117 DLL4 DLL4 ENSCATP00000034768 ENSCATP00000034768 ENSCATP00000035052 ENSCATP00000035052 ENSCATP00000035134 ENSCATP00000035134 JAG1 JAG1 ENSCATP00000041490 ENSCATP00000041490 RPS27A RPS27A KAT2A KAT2A PSME3 PSME3 EP300 EP300 PSMD11 PSMD11 PSEN2 PSEN2 PSMB5 PSMB5 RBPJ RBPJ PSMD5 PSMD5 SNW1 SNW1 PSME2 PSME2 CUL1 CUL1 PSMD3 PSMD3 ADAM10 ADAM10 LOC105579396 LOC105579396 NOTCH1 NOTCH1 PSMD7 PSMD7 YWHAZ YWHAZ PSMB8 PSMB8 TACC3 TACC3 MAMLD1 MAMLD1 HES4 HES4 PSMA2 PSMA2 ENSCATP00000037470 ENSCATP00000037470 PSMB6 PSMB6 ENSCATP00000037714 ENSCATP00000037714 NOTCH2 NOTCH2 PSMA4 PSMA4 PSMB9 PSMB9 ENSCATP00000010732 ENSCATP00000010732 ENSCATP00000011745 ENSCATP00000011745 ENSCATP00000011971 ENSCATP00000011971 PSMD6 PSMD6 CRB1 CRB1 PSMD4 PSMD4 SKP1 SKP1 PSMD13 PSMD13 PSMC4 PSMC4 PSMD14 PSMD14 ENSCATP00000040310 ENSCATP00000040310 HES5 HES5 PSENEN PSENEN PSMC1 PSMC1 ENSCATP00000031033 ENSCATP00000031033 NOTCH4 NOTCH4 PSEN1 PSEN1 PSMB2 PSMB2 PSMB4 PSMB4 PSMA3 PSMA3 CREBBP CREBBP PSMC2 PSMC2 FBXW7 FBXW7 ENSCATP00000034742 ENSCATP00000034742 PSMC6 PSMC6 APH1B APH1B ENSCATP00000014541 ENSCATP00000014541 ENSCATP00000014620 ENSCATP00000014620 PSMB3 PSMB3 ENSCATP00000015253 ENSCATP00000015253 ENSCATP00000016334 ENSCATP00000016334 ENSCATP00000016481 ENSCATP00000016481 UBA52 UBA52 LOC105579883 LOC105579883 PSMB10 PSMB10 PSMD12 PSMD12 KAT2B KAT2B PSMA5 PSMA5 PSMD10 PSMD10 ENSCATP00000020004 ENSCATP00000020004 PSMB7 PSMB7 ENSCATP00000020357 ENSCATP00000020357 PSMC5 PSMC5 APH1A APH1A ENSCATP00000021172 ENSCATP00000021172 PSME1 PSME1 MAML2 MAML2 PSMD9 PSMD9 HES1 HES1 HEY2 HEY2 FLT4 FLT4 ENSCATP00000023795 ENSCATP00000023795 MAML1 MAML1 PSMB1 PSMB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBX1Ring-box 1. (108 aa)
NCSTNNicastrin. (721 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSCATP00000004934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
ENSCATP00000003644ANK_REP_REGION domain-containing protein. (116 aa)
ENSCATP0000000336414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
ENSCATP00000000117Uncharacterized protein. (93 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
ENSCATP00000035052Uncharacterized protein. (211 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ENSCATP00000041490AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
PSME3Proteasome activator subunit 3. (265 aa)
EP300E1A binding protein p300. (2411 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
PSMB5Proteasome subunit beta. (263 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (488 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (508 aa)
SNW1SNW domain containing 1. (598 aa)
PSME2Proteasome activator subunit 2. (239 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
NOTCH1Notch receptor 1. (2547 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
PSMB8Proteasome subunit beta. (276 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
MAMLD1Mastermind like domain containing 1. (1003 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ENSCATP00000037470AAA domain-containing protein. (389 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSCATP0000003771414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (232 aa)
NOTCH2Notch receptor 2. (2610 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
PSMB9Proteasome subunit beta. (219 aa)
ENSCATP00000010732CSN8_PSD8_EIF3K domain-containing protein. (249 aa)
ENSCATP00000011745AAA domain-containing protein. (410 aa)
ENSCATP00000011971Uncharacterized protein. (191 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
CRB1Crumbs cell polarity complex component 1. (1394 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (363 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (379 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
ENSCATP00000040310ANK_REP_REGION domain-containing protein. (159 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
NOTCH4Notch receptor 4. (2000 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CREBBPCREB binding protein. (2442 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
ENSCATP00000034742JAB_MPN domain-containing protein. (166 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
ENSCATP00000014541Prot_ATP_ID_OB domain-containing protein. (172 aa)
ENSCATP00000014620SKIP_SNW domain-containing protein. (480 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSCATP00000015253AAA domain-containing protein. (373 aa)
ENSCATP00000016334Uncharacterized protein. (338 aa)
ENSCATP00000016481AAA domain-containing protein. (370 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
LOC105579883Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (238 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSCATP00000020004Uncharacterized protein; Belongs to the SKP1 family. (198 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSCATP00000020357AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ENSCATP00000021172Uncharacterized protein. (278 aa)
PSME1Proteasome activator subunit 1. (249 aa)
MAML2Mastermind like transcriptional coactivator 2. (1151 aa)
PSMD9PDZ domain-containing protein. (223 aa)
HES1Hes family bHLH transcription factor 1. (326 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
ENSCATP0000002379514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (238 aa)
MAML1Mastermind like transcriptional coactivator 1. (963 aa)
PSMB1Proteasome subunit beta. (241 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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