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KATNAL1 KATNAL1 ABCA5 ABCA5 CFTR CFTR CHTF18 CHTF18 ORC4 ORC4 MDN1 MDN1 DNAH2 DNAH2 ATAD5 ATAD5 ABCB5 ABCB5 TOR2A TOR2A DNAH7 DNAH7 CLPB CLPB ABCB6 ABCB6 ENSCATP00000043096 ENSCATP00000043096 ABCD4 ABCD4 ENSCATP00000041918 ENSCATP00000041918 ENSCATP00000041490 ENSCATP00000041490 ORC1 ORC1 ABCA2 ABCA2 RNF213 RNF213 PSMC4 PSMC4 ABCA12 ABCA12 GPN1 GPN1 ABCF3 ABCF3 WRNIP1 WRNIP1 NSF NSF ABCG4 ABCG4 ENSCATP00000037470 ENSCATP00000037470 ABCB4 ABCB4 CLPX CLPX YME1L1 YME1L1 ABCF1 ABCF1 DNAH10 DNAH10 ABCB10 ABCB10 ABCC1 ABCC1 ABCC4 ABCC4 LONP1 LONP1 NTPCR NTPCR SPAST SPAST NVL NVL DNAH9 DNAH9 DDX58 DDX58 RAD51C RAD51C DNAH14 DNAH14 ABCC9 ABCC9 MCM9 MCM9 PSMC2 PSMC2 MCM7 MCM7 TAP2 TAP2 PSMC1 PSMC1 ABCD2 ABCD2 AK9 AK9 PEX6 PEX6 DNAH3 DNAH3 NAV2 NAV2 KATNA1 KATNA1 RUVBL2 RUVBL2 ATP5F1B ATP5F1B ABCA6 ABCA6 ABCG2 ABCG2 VPS4B VPS4B KATNAL2 KATNAL2 ENSCATP00000027317 ENSCATP00000027317 MCM8 MCM8 ABCE1 ABCE1 ABCC11 ABCC11 SPATA5 SPATA5 ABCD3 ABCD3 DNAH5 DNAH5 ABCB9 ABCB9 ATAD2B ATAD2B ABCG5 ABCG5 ABCA1 ABCA1 PEX1 PEX1 ABCF2 ABCF2 ABCA13 ABCA13 ABCA8 ABCA8 RAD51D RAD51D PSMC5 PSMC5 TAP1 TAP1 ENSCATP00000020357 ENSCATP00000020357 SPATA5L1 SPATA5L1 ABCC12 ABCC12 VWA8 VWA8 DYNC1H1 DYNC1H1 ENSCATP00000018270 ENSCATP00000018270 AFG3L2 AFG3L2 LOC105571889 LOC105571889 ENSCATP00000016481 ENSCATP00000016481 FIGN FIGN NAV3 NAV3 LOC105589328 LOC105589328 RAD51B RAD51B ABCC8 ABCC8 ENSCATP00000015253 ENSCATP00000015253 MCM3 MCM3 MCM4 MCM4 ABCB8 ABCB8 IGHMBP2 IGHMBP2 MMAA MMAA PSMC6 PSMC6 CDC6 CDC6 RUVBL1 RUVBL1 ABCA9 ABCA9 RFC2 RFC2 ABCB11 ABCB11 RFC4 RFC4 ENSCATP00000011745 ENSCATP00000011745 ABCA7 ABCA7 TRIP13 TRIP13 ABCC5 ABCC5 ATAD2 ATAD2 ABCC2 ABCC2 ABCA10 ABCA10 LONP2 LONP2 SPG7 SPG7 ABCC10 ABCC10 VCP VCP DYNC2H1 DYNC2H1 DNAH8 DNAH8 DNAH11 DNAH11 PSMC3 PSMC3 NAV1 NAV1 ABCA3 ABCA3 ABCG1 ABCG1 FIGNL2 FIGNL2 SNRNP200 SNRNP200 DNAH6 DNAH6 RFC1 RFC1 VPS4A VPS4A HELZ2 HELZ2 RFC5 RFC5 ABCA4 ABCA4 DNAH12 DNAH12 RFC3 RFC3 BCS1L BCS1L ASCC3 ASCC3 ATAD1 ATAD1 NAIP NAIP ABCC6 ABCC6 ABCB7 ABCB7 DHX15 DHX15
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
ABCA5ATP binding cassette subfamily A member 5. (1646 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
CHTF18Chromosome transmission fidelity factor 18. (1003 aa)
ORC4Origin recognition complex subunit 4. (339 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5597 aa)
DNAH2Dynein axonemal heavy chain 2. (4427 aa)
ATAD5ATPase family AAA domain containing 5. (1832 aa)
ABCB5ATP binding cassette subfamily B member 5. (1242 aa)
TOR2ATorsin. (321 aa)
DNAH7Dynein axonemal heavy chain 7. (4024 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (704 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (856 aa)
ENSCATP00000043096ABC transporter domain-containing protein. (602 aa)
ABCD4ATP binding cassette subfamily D member 4. (612 aa)
ENSCATP00000041918Uncharacterized protein. (546 aa)
ENSCATP00000041490AAA domain-containing protein; Belongs to the AAA ATPase family. (199 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
ABCA2ATP binding cassette subfamily A member 2. (2549 aa)
RNF213Ring finger protein 213. (5210 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
GPN1GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (389 aa)
ABCF3ATP binding cassette subfamily F member 3. (709 aa)
WRNIP1WRN helicase interacting protein 1. (665 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (744 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
ENSCATP00000037470AAA domain-containing protein. (389 aa)
ABCB4ATP binding cassette subfamily B member 4. (1409 aa)
CLPXUncharacterized protein. (633 aa)
YME1L1YME1 like 1 ATPase. (765 aa)
ABCF1ATP binding cassette subfamily F member 1. (947 aa)
DNAH10Dynein axonemal heavy chain 10. (4526 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
ABCC1ATP binding cassette subfamily C member 1. (1537 aa)
ABCC4ATP binding cassette subfamily C member 4. (1325 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)
NTPCRNucleoside-triphosphatase, cancer-related. (227 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (599 aa)
NVLNuclear VCP like. (858 aa)
DNAH9Dynein axonemal heavy chain 9. (4474 aa)
DDX58DExD/H-box helicase 58. (925 aa)
RAD51CRAD51 paralog C. (367 aa)
DNAH14Uncharacterized protein. (4500 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
TAP2Transporter 2, ATP binding cassette subfamily B member. (711 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
AK9Adenylate kinase 9. (1914 aa)
PEX6Peroxisomal biogenesis factor 6. (980 aa)
DNAH3Dynein axonemal heavy chain 3. (4053 aa)
NAV2Neuron navigator 2. (2465 aa)
KATNA1Katanin catalytic subunit A1; Belongs to the AAA ATPase family. (322 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (465 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (486 aa)
ABCA6ATP binding cassette subfamily A member 6. (1600 aa)
ABCG2ABC transporter domain-containing protein. (655 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (532 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
ENSCATP00000027317AAA domain-containing protein; Belongs to the AAA ATPase family. (343 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (880 aa)
ABCE1ATP binding cassette subfamily E member 1. (599 aa)
ABCC11ATP binding cassette subfamily C member 11. (1178 aa)
SPATA5Spermatogenesis associated 5. (852 aa)
ABCD3ATP binding cassette subfamily D member 3. (659 aa)
DNAH5Dynein axonemal heavy chain 5. (4624 aa)
ABCB9ATP binding cassette subfamily B member 9. (766 aa)
ATAD2BATPase family AAA domain containing 2B. (1458 aa)
ABCG5ATP binding cassette subfamily G member 5. (651 aa)
ABCA1ATP binding cassette subfamily A member 1. (2258 aa)
PEX1Peroxisomal biogenesis factor 1. (1283 aa)
ABCF2Uncharacterized protein. (635 aa)
ABCA13ATP binding cassette subfamily A member 13. (5003 aa)
ABCA8ATP binding cassette subfamily A member 8. (1621 aa)
RAD51DDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (346 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (808 aa)
ENSCATP00000020357AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (740 aa)
ABCC12ATP binding cassette subfamily C member 12. (1359 aa)
VWA8Von Willebrand factor A domain containing 8. (1905 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4673 aa)
ENSCATP00000018270AAA domain-containing protein. (497 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (800 aa)
LOC105571889Uncharacterized protein. (1267 aa)
ENSCATP00000016481AAA domain-containing protein. (370 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
NAV3Neuron navigator 3. (2383 aa)
LOC105589328AAA domain-containing protein. (683 aa)
RAD51BRAD51 paralog B. (425 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
ENSCATP00000015253AAA domain-containing protein. (373 aa)
MCM3DNA helicase; Belongs to the MCM family. (853 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
ABCB8ATP binding cassette subfamily B member 8. (735 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (938 aa)
MMAAMetabolism of cobalamin associated A. (421 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (599 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ABCA9ATP binding cassette subfamily A member 9. (1624 aa)
RFC2Replication factor C subunit 2. (352 aa)
ABCB11ATP binding cassette subfamily B member 11. (1317 aa)
RFC4Replication factor C subunit 4. (349 aa)
ENSCATP00000011745AAA domain-containing protein. (410 aa)
ABCA7ATP binding cassette subfamily A member 7. (2140 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
ATAD2ATPase family AAA domain containing 2. (1382 aa)
ABCC2ATP binding cassette subfamily C member 2. (1545 aa)
ABCA10ATP binding cassette subfamily A member 10. (1545 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (825 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (794 aa)
ABCC10ATP binding cassette subfamily C member 10. (1492 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4314 aa)
DNAH8Dynein axonemal heavy chain 8. (4638 aa)
DNAH11Dynein axonemal heavy chain 11. (4578 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
NAV1Neuron navigator 1. (1877 aa)
ABCA3ATP binding cassette subfamily A member 3. (1704 aa)
ABCG1ATP binding cassette subfamily G member 1. (706 aa)
FIGNL2Fidgetin like 2. (652 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
DNAH6Dynein axonemal heavy chain 6. (4158 aa)
RFC1Replication factor C subunit 1. (1113 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (501 aa)
HELZ2Helicase with zinc finger 2. (2849 aa)
RFC5Replication factor C subunit 5. (343 aa)
ABCA4ATP binding cassette subfamily A member 4. (2273 aa)
DNAH12Uncharacterized protein. (3960 aa)
RFC3Replication factor C subunit 3. (356 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2202 aa)
ATAD1AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
NAIPNLR family apoptosis inhibitory protein. (1403 aa)
ABCC6ATP binding cassette subfamily C member 6. (1444 aa)
ABCB7ATP binding cassette subfamily B member 7. (753 aa)
DHX15DEAH-box helicase 15. (795 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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