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ASMTL ASMTL ECHS1 ECHS1 ACAD10 ACAD10 TTLL12 TTLL12 AADAT AADAT ALDH16A1 ALDH16A1 DDC DDC CYP1B1 CYP1B1 FIGNL2 FIGNL2 ALDH1B1 ALDH1B1 LOC105584179 LOC105584179 ALDH3A2 ALDH3A2 LOC105580200 LOC105580200 DLST DLST EHHADH EHHADH GCDH GCDH MAOA MAOA ASMT ASMT ACAT1 ACAT1 ACAT2 ACAT2 HAAO HAAO HADHA HADHA FIGN FIGN DLD DLD INMT INMT IDO1 IDO1 MAOB MAOB AOX1 AOX1 TDO2 TDO2 CAT CAT ACMSD ACMSD AANAT AANAT IDO2 IDO2 CYP1A2 CYP1A2 AFMID AFMID ALDH7A1 ALDH7A1 DHTKD1 DHTKD1 CYP1A1 CYP1A1 ACAD11 ACAD11 TPH2 TPH2 KATNAL2 KATNAL2 KMO KMO GTPBP1 GTPBP1 KYAT3 KYAT3 KYNU KYNU AOC1 AOC1 ALDH2 ALDH2 ALDH9A1 ALDH9A1 TPH1 TPH1 SPAST SPAST HADH HADH ENSCATP00000037772 ENSCATP00000037772 LOC105580021 LOC105580021 CARTPT CARTPT KYAT1 KYAT1 WDTC1 WDTC1 IL4I1 IL4I1 ALDH8A1 ALDH8A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASMTLAcetylserotonin O-methyltransferase like. (615 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1011 aa)
TTLL12Tubulin tyrosine ligase like 12. (644 aa)
AADATAminoadipate aminotransferase. (425 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (802 aa)
DDCDopa decarboxylase. (466 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (547 aa)
FIGNL2Fidgetin like 2. (652 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
LOC105584179Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
LOC105580200FAD-binding PCMH-type domain-containing protein. (1342 aa)
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
MAOAAmine oxidase. (527 aa)
ASMTAcetylserotonin O-methyltransferase. (331 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
ACAT2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha. (748 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
DLDDihydrolipoyl dehydrogenase. (517 aa)
INMTUncharacterized protein. (263 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
MAOBAmine oxidase. (520 aa)
AOX1Aldehyde oxidase 1. (1338 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
AANATAralkylamine N-acetyltransferase. (246 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (420 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
AFMIDArylformamidase. (294 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (551 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (889 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (470 aa)
GTPBP1GTP binding protein 1. (669 aa)
KYAT3Kynurenine aminotransferase 3. (454 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (440 aa)
AOC1Amine oxidase. (755 aa)
ALDH2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
ALDH9A1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (518 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (599 aa)
HADHHydroxyacyl-CoA dehydrogenase. (317 aa)
ENSCATP00000037772Thiolase_N domain-containing protein. (276 aa)
LOC105580021Uncharacterized protein. (1326 aa)
CARTPTCART prepropeptide. (116 aa)
KYAT1Aminotran_1_2 domain-containing protein. (515 aa)
WDTC1WD and tetratricopeptide repeats 1. (687 aa)
IL4I1Amine oxidase. (589 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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