STRINGSTRING
ENSCATP00000045990 ENSCATP00000045990 CNOT9 CNOT9 DIS3 DIS3 DHX36 DHX36 EDC3 EDC3 CNOT7 CNOT7 PLXDC2 PLXDC2 CNOT2 CNOT2 ENSCATP00000046006 ENSCATP00000046006 LOC105582850 LOC105582850 ENSCATP00000008723 ENSCATP00000008723 PABPC1L PABPC1L TTC37 TTC37 CNOT8 CNOT8 TOE1 TOE1 ZCCHC2 ZCCHC2 PFKL PFKL DPH1 DPH1 ENSCATP00000031352 ENSCATP00000031352 DDX60 DDX60 IPO8 IPO8 ENSCATP00000031508 ENSCATP00000031508 CCT4 CCT4 PNLDC1 PNLDC1 CCT3 CCT3 CNOT1 CNOT1 C19orf54 C19orf54 NUDT6 NUDT6 ERMARD ERMARD LOC105581026 LOC105581026 LRRC27 LRRC27 MKKS MKKS NUDT18 NUDT18 TENT4B TENT4B LSM3-2 LSM3-2 PNPT1 PNPT1 EXOSC2 EXOSC2 ENSCATP00000008302 ENSCATP00000008302 LSM7 LSM7 CNOT4 CNOT4 TOB1 TOB1 ENSCATP00000007492 ENSCATP00000007492 ZCCHC3 ZCCHC3 BTG4 BTG4 TMEM87B TMEM87B EXOSC4 EXOSC4 DCP2 DCP2 VPS72 VPS72 LSM6 LSM6 DPH2 DPH2 LOC105591903 LOC105591903 CNOT6L CNOT6L PFKP PFKP LSM4 LSM4 PABPC3 PABPC3 DCPS DCPS DCP1B DCP1B LOC105586448 LOC105586448 PLXDC1 PLXDC1 ENSCATP00000014142 ENSCATP00000014142 MPHOSPH6 MPHOSPH6 PAN3 PAN3 LOC105596933 LOC105596933 CCT5 CCT5 DHX57 DHX57 ENSCATP00000013055 ENSCATP00000013055 PPIC PPIC ENSCATP00000012892 ENSCATP00000012892 BTG1 BTG1 ENO1 ENO1 ENSCATP00000026762 ENSCATP00000026762 DHX29 DHX29 SLC30A7 SLC30A7 EXOSC7 EXOSC7 ENSCATP00000026028 ENSCATP00000026028 CWH43 CWH43 ENSCATP00000025852 ENSCATP00000025852 UFSP2 UFSP2 TOB2 TOB2 ZCCHC7 ZCCHC7 LSM1 LSM1 CNBP CNBP ENSCATP00000006293 ENSCATP00000006293 SLC30A6 SLC30A6 ENSCATP00000004528 ENSCATP00000004528 LSM5-2 LSM5-2 CCT6A CCT6A PAM PAM HELZ2 HELZ2 LSM2 LSM2 ENSCATP00000012545 ENSCATP00000012545 LOC105574569 LOC105574569 LOC105582103 LOC105582103 PATL2 PATL2 CCT2 CCT2 ZCCHC9 ZCCHC9 EXD2 EXD2 LOC105576701 LOC105576701 ENSCATP00000040481 ENSCATP00000040481 ENSCATP00000040841 ENSCATP00000040841 PABPC5 PABPC5 LOC105576702 LOC105576702 ENSCATP00000003094 ENSCATP00000003094 UFSP1 UFSP1 PATL1 PATL1 ENSCATP00000002114 ENSCATP00000002114 CBWD1 CBWD1 LOC105572333 LOC105572333 DHX30 DHX30 WDR61 WDR61 BTG3 BTG3 PPP4R2 PPP4R2 EXOSC3 EXOSC3 DCP1A DCP1A EXOSC5 EXOSC5 HSPD1 HSPD1 DDX60L DDX60L EXOSC9 EXOSC9 EDC4 EDC4 DIS3L2 DIS3L2 CNOT3 CNOT3 PDE12 PDE12 DIS3L DIS3L ENSCATP00000045093 ENSCATP00000045093 DDX6 DDX6 PFKM PFKM PAN2 PAN2 BTG2 BTG2 LSM8 LSM8 SKIV2L SKIV2L EXOSC10 EXOSC10 PABPC1 PABPC1 ENSCATP00000032649 ENSCATP00000032649 LSM3 LSM3 CCT6B CCT6B SLC30A5 SLC30A5 NAXE NAXE LSM5 LSM5 ENO4 ENO4 PPIB PPIB XRN2 XRN2 TCP1 TCP1 EXOSC8 EXOSC8 WRN WRN LOC105577057 LOC105577057 NUDT16 NUDT16 PARN PARN TMEM176B TMEM176B KIFBP KIFBP NOCT NOCT CCT7 CCT7 XRN1 XRN1 HSPA9 HSPA9 WRAP73 WRAP73 CNOT6 CNOT6 BBS10 BBS10 MTREX MTREX TENT4A TENT4A ENSCATP00000021515 ENSCATP00000021515 PABPC4 PABPC4 CNOT10 CNOT10 TMEM87A TMEM87A ENO2 ENO2 IPO7 IPO7 EXOSC1 EXOSC1 C1D C1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000045990Uncharacterized protein. (565 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (330 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
DHX36DEAH-box helicase 36. (1011 aa)
EDC3Enhancer of mRNA decapping 3. (508 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
PLXDC2Plexin domain containing 2. (529 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (548 aa)
ENSCATP00000046006Uncharacterized protein. (525 aa)
LOC105582850T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (467 aa)
ENSCATP00000008723T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (53 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
TTC37Tetratricopeptide repeat domain 37. (1564 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
TOE1Target of EGR1, exonuclease. (522 aa)
ZCCHC2Zinc finger CCHC-type containing 2. (1157 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (778 aa)
DPH12-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (443 aa)
ENSCATP00000031352Sm domain-containing protein. (71 aa)
DDX60DExD/H-box helicase 60. (1712 aa)
IPO8Importin 8. (1037 aa)
ENSCATP00000031508Uncharacterized protein. (318 aa)
CCT4T-complex protein 1 subunit delta. (509 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (531 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2376 aa)
C19orf54Chromosome 19 open reading frame 54. (351 aa)
NUDT6Nudix hydrolase 6; Belongs to the Nudix hydrolase family. (316 aa)
ERMARDER membrane associated RNA degradation. (669 aa)
LOC105581026Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (555 aa)
LRRC27Leucine rich repeat containing 27. (529 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
NUDT18Nudix hydrolase 18; Belongs to the Nudix hydrolase family. (323 aa)
TENT4BTerminal nucleotidyltransferase 4B. (676 aa)
LSM3-2U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (92 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (779 aa)
EXOSC2Uncharacterized protein. (293 aa)
ENSCATP00000008302Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (713 aa)
TOB1Transducer of ERBB2, 1. (345 aa)
ENSCATP00000007492Anti_prolifrtn domain-containing protein. (171 aa)
ZCCHC3Zinc finger CCHC-type containing 3. (402 aa)
BTG4BTG anti-proliferation factor 4. (229 aa)
TMEM87BTransmembrane protein 87B. (556 aa)
EXOSC4Exosome component 4. (260 aa)
DCP2Decapping mRNA 2. (420 aa)
VPS72Vacuolar protein sorting 72 homolog. (374 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
DPH22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (489 aa)
LOC105591903Uncharacterized protein. (363 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (562 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (770 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (231 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (630 aa)
DCPSDecapping enzyme, scavenger. (339 aa)
DCP1BDecapping mRNA 1B. (618 aa)
LOC105586448Nudix hydrolase domain-containing protein. (206 aa)
PLXDC1Plexin domain containing 1. (500 aa)
ENSCATP00000014142Uncharacterized protein. (317 aa)
MPHOSPH6M-phase phosphoprotein 6. (160 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (936 aa)
LOC105596933Uncharacterized protein. (521 aa)
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
DHX57DExH-box helicase 57. (1387 aa)
ENSCATP00000013055Uncharacterized protein; Belongs to the heat shock protein 70 family. (624 aa)
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (220 aa)
ENSCATP00000012892Uncharacterized protein. (226 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
ENO1Enolase 1. (434 aa)
ENSCATP00000026762Uncharacterized protein. (317 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1367 aa)
SLC30A7Solute carrier family 30 member 7. (376 aa)
EXOSC7Exosome component 7. (293 aa)
ENSCATP00000026028S1 motif domain-containing protein. (655 aa)
CWH43Cell wall biogenesis 43 C-terminal homolog. (699 aa)
ENSCATP00000025852Uncharacterized protein. (506 aa)
UFSP2UFM1 specific peptidase 2. (470 aa)
TOB2Transducer of ERBB2, 2. (335 aa)
ZCCHC7Zinc finger CCHC-type containing 7. (543 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
CNBPCCHC-type zinc finger nucleic acid binding protein. (177 aa)
ENSCATP00000006293Uncharacterized protein. (70 aa)
SLC30A6Solute carrier family 30 member 6. (461 aa)
ENSCATP00000004528Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (140 aa)
LSM5-2U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (82 aa)
CCT6AUncharacterized protein. (566 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (975 aa)
HELZ2Helicase with zinc finger 2. (2849 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
ENSCATP00000012545Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (112 aa)
LOC105574569Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (580 aa)
LOC105582103KH_dom_type_1 domain-containing protein. (275 aa)
PATL2PAT1 homolog 2. (546 aa)
CCT2Chaperonin containing TCP1 subunit 2. (589 aa)
ZCCHC9Uncharacterized protein. (270 aa)
EXD2Exonuclease 3'-5' domain containing 2. (620 aa)
LOC105576701Uncharacterized protein. (200 aa)
ENSCATP00000040481Uncharacterized protein. (411 aa)
ENSCATP00000040841Uncharacterized protein. (248 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
LOC105576702Polyadenylate-binding protein 1-like 2. (200 aa)
ENSCATP00000003094Endo/exonuclease/phosphatase domain-containing protein. (354 aa)
UFSP1UFM1 specific peptidase 1 (inactive). (142 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (770 aa)
ENSCATP00000002114Uncharacterized protein. (431 aa)
CBWD1CobW C-terminal domain-containing protein. (395 aa)
LOC105572333Uncharacterized protein. (141 aa)
DHX30DExH-box helicase 30. (1222 aa)
WDR61WD repeat domain 61. (305 aa)
BTG3BTG anti-proliferation factor 3. (291 aa)
PPP4R2Uncharacterized protein. (417 aa)
EXOSC3Exosome component 3. (275 aa)
DCP1ADecapping mRNA 1A. (582 aa)
EXOSC5Exosome component 5. (235 aa)
HSPD1Heat shock protein family D (Hsp60) member 1. (523 aa)
DDX60LDExD/H-box 60 like. (1712 aa)
EXOSC9Exosome component 9. (456 aa)
EDC4Enhancer of mRNA decapping 4. (1403 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (875 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (784 aa)
PDE12Phosphodiesterase 12. (609 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1053 aa)
ENSCATP00000045093Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (572 aa)
DDX6DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1216 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
EXOSC10Exosome component 10. (884 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
ENSCATP00000032649Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (572 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (535 aa)
SLC30A5Solute carrier family 30 member 5. (762 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
ENO4Enolase 4. (627 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
TCP1Uncharacterized protein. (556 aa)
EXOSC8Exosome component 8. (276 aa)
WRNWRN RecQ like helicase. (1418 aa)
LOC105577057Uncharacterized protein. (353 aa)
NUDT16Nudix hydrolase domain-containing protein. (195 aa)
PARNPoly(A)-specific ribonuclease. (575 aa)
TMEM176BTransmembrane protein 176B. (268 aa)
KIFBPKIF1 binding protein. (646 aa)
NOCTEndo/exonuclease/phosphatase domain-containing protein. (431 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (481 aa)
XRN15'-3' exoribonuclease 1. (1707 aa)
HSPA9Uncharacterized protein; Belongs to the heat shock protein 70 family. (679 aa)
WRAP73WD repeat containing, antisense to TP73. (454 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
BBS10Bardet-Biedl syndrome 10. (720 aa)
MTREXMtr4 exosome RNA helicase. (1051 aa)
TENT4ATerminal nucleotidyltransferase 4A. (727 aa)
ENSCATP00000021515Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (560 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (804 aa)
TMEM87ATransmembrane protein 87A. (555 aa)
ENO2Enolase 2. (434 aa)
IPO7Importin 7. (993 aa)
EXOSC1Exosome component 1. (195 aa)
C1DC1D nuclear receptor corepressor. (141 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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