STRINGSTRING
RIT1 RIT1 EIF2AK3 EIF2AK3 RRAS RRAS USP31 USP31 CALCOCO2 CALCOCO2 AGFG2 AGFG2 MAPK8 MAPK8 ENSCATP00000002569 ENSCATP00000002569 GABARAP GABARAP FIS1 FIS1 REM2 REM2 HIF3A HIF3A ENSCATP00000003653 ENSCATP00000003653 USP15 USP15 SRC SRC SPEN SPEN ERAS ERAS SP1 SP1 LOC105576738 LOC105576738 PDIK1L PDIK1L LOC105579396 LOC105579396 LOC105595668 LOC105595668 HIF1A HIF1A CSNK2A2 CSNK2A2 FUNDC2 FUNDC2 ULK1 ULK1 TBC1D17 TBC1D17 MFN2 MFN2 GABARAPL2 GABARAPL2 PINK1 PINK1 TFE3 TFE3 STK35 STK35 ENSCATP00000011488 ENSCATP00000011488 NPAS3 NPAS3 KRAS KRAS USP32 USP32 ATF4 ATF4 HRAS HRAS RAB7B RAB7B CITED2 CITED2 UBA52 UBA52 GEM GEM TBC1D15 TBC1D15 ATG5 ATG5 TFEB TFEB LOC105589083 LOC105589083 PRKN PRKN ENSCATP00000018866 ENSCATP00000018866 MFN1 MFN1 MAPK9 MAPK9 RIT2 RIT2 SQSTM1 SQSTM1 BCL2L1 BCL2L1 RRAD RRAD USP11 USP11 RASL11B RASL11B TFEC TFEC MITF MITF BCL2L13 BCL2L13 PGAM5 PGAM5 RHOT1 RHOT1 BNIP3L BNIP3L CSDE1 CSDE1 USP43 USP43 AMBRA1 AMBRA1 ATG9A ATG9A USP4 USP4 ENSCATP00000030993 ENSCATP00000030993 ENSCATP00000031033 ENSCATP00000031033 TOMM7 TOMM7 NBR1 NBR1 TP53 TP53 FOXO3 FOXO3 E2F1 E2F1 ATG9B ATG9B FUNDC1 FUNDC1 OPTN OPTN ENSCATP00000034768 ENSCATP00000034768 ENSCATP00000035134 ENSCATP00000035134 METTL17 METTL17 CSNK2B CSNK2B BECN1 BECN1 RELA RELA TAX1BP1 TAX1BP1 NRAS NRAS USP19 USP19 AGFG1 AGFG1 RHOT2 RHOT2 REM1 REM1 CFAP70 CFAP70 TBK1 TBK1 USP30 USP30 USP8 USP8 RRAS2 RRAS2 RPS27A RPS27A ENSCATP00000041990 ENSCATP00000041990 MRAS MRAS MAPK10 MAPK10 GABARAPL1 GABARAPL1 CSNK2A1 CSNK2A1 ENSCATP00000043644 ENSCATP00000043644 NPAS1 NPAS1 BNIP3 BNIP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIT1Ras like without CAAX 1. (236 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (964 aa)
RRASRAS related. (218 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1352 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (470 aa)
AGFG2ArfGAP with FG repeats 2. (490 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
ENSCATP00000002569Uncharacterized protein. (151 aa)
GABARAPUncharacterized protein. (117 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (759 aa)
ENSCATP00000003653Uncharacterized protein. (189 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
SRCTyrosine-protein kinase. (644 aa)
SPENSpen family transcriptional repressor. (3673 aa)
ERASES cell expressed Ras. (233 aa)
SP1Sp1 transcription factor. (786 aa)
LOC105576738Ubiquitin-like domain-containing protein. (134 aa)
PDIK1LPDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily. (341 aa)
LOC105579396Ubiquitin-like domain-containing protein. (156 aa)
LOC105595668Ubiquitin-like domain-containing protein. (126 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (831 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
FUNDC2FUN14 domain containing 2. (189 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1038 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
PINK1PTEN induced kinase 1. (581 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
STK35Serine/threonine kinase 35. (533 aa)
ENSCATP00000011488Uncharacterized protein. (91 aa)
NPAS3Neuronal PAS domain protein 3. (936 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
USP32Uncharacterized protein; Belongs to the peptidase C19 family. (1576 aa)
ATF4Activating transcription factor 4. (351 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RAB7BRAB7B, member RAS oncogene family. (202 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
TBC1D15TBC1 domain family member 15. (693 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TFEBTranscription factor EB. (490 aa)
LOC105589083Uncharacterized protein. (911 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ENSCATP00000018866Uncharacterized protein. (194 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
RIT2Ras like without CAAX 2. (217 aa)
SQSTM1Sequestosome 1. (440 aa)
BCL2L1BCL2 like 1. (233 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (970 aa)
RASL11BRAS like family 11 member B. (248 aa)
TFECTranscription factor EC. (347 aa)
MITFMelanocyte inducing transcription factor. (519 aa)
BCL2L13BCL2 like 13. (509 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa)
RHOT1Ras homolog family member T1. (752 aa)
BNIP3LBCL2 interacting protein 3 like. (179 aa)
CSDE1Cold shock domain containing E1. (844 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1012 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (848 aa)
USP4Ubiquitin specific peptidase 4; Belongs to the peptidase C19 family. (952 aa)
ENSCATP00000030993Uncharacterized protein. (146 aa)
ENSCATP00000031033Ubiquitin-like domain-containing protein. (149 aa)
TOMM7Uncharacterized protein. (125 aa)
NBR1ZZ-type domain-containing protein. (967 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
FOXO3Forkhead box O3. (672 aa)
E2F1E2F transcription factor 1. (437 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
OPTNOptineurin. (571 aa)
ENSCATP00000034768Ubiquitin-like domain-containing protein. (144 aa)
ENSCATP00000035134Ubiquitin-like domain-containing protein. (146 aa)
METTL17Methyltransferase like 17. (459 aa)
CSNK2BUncharacterized protein. (298 aa)
BECN1Beclin 1. (450 aa)
RELARELA proto-oncogene, NF-kB subunit. (550 aa)
TAX1BP1Tax1 binding protein 1. (787 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
USP19Ubiquitin specific peptidase 19. (1421 aa)
AGFG1ArfGAP with FG repeats 1. (585 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (629 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
CFAP70Cilia and flagella associated protein 70. (1122 aa)
TBK1TANK binding kinase 1. (729 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
RRAS2RAS related 2. (204 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCATP00000041990Uncharacterized protein. (114 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
MAPK10Mitogen-activated protein kinase. (474 aa)
GABARAPL1GABA type A receptor associated protein like 1. (145 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
ENSCATP00000043644Ubiquitin-like domain-containing protein. (120 aa)
NPAS1Neuronal PAS domain protein 1. (591 aa)
BNIP3BCL2 interacting protein 3. (194 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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