STRINGSTRING
ENSCATP00000000676 ENSCATP00000000676 FZD5 FZD5 FZD7 FZD7 FZD9 FZD9 FGF2 FGF2 SMAD2 SMAD2 ACVR1C ACVR1C DUSP9 DUSP9 SMAD3 SMAD3 INHBB INHBB FZD4 FZD4 TCF3 TCF3 LOC105578089 LOC105578089 WNT2B WNT2B ERAS ERAS SOX2 SOX2 INHBC INHBC LOC105576936 LOC105576936 KLF4 KLF4 AKT1 AKT1 MAPK13 MAPK13 NFIL3 NFIL3 FZD10 FZD10 WNT8A WNT8A NEUROG1 NEUROG1 JAK3 JAK3 SOX3 SOX3 ZFHX3 ZFHX3 SOX1 SOX1 ENSCATP00000008104 ENSCATP00000008104 WNT3A WNT3A JAK2 JAK2 ID3 ID3 IGF1R IGF1R WNT4 WNT4 MAPK11 MAPK11 ESX1 ESX1 ENSCATP00000010452 ENSCATP00000010452 BMPR1B BMPR1B MAPK3 MAPK3 WNT1 WNT1 KRAS KRAS PRRX1 PRRX1 ID2 ID2 ONECUT2 ONECUT2 WNT5B WNT5B APC APC MAP2K2 MAP2K2 ESRRB ESRRB MEIS1 MEIS1 WNT3 WNT3 HRAS HRAS FZD8 FZD8 FZD6 FZD6 BMI1 BMI1 ENSCATP00000015541 ENSCATP00000015541 ID1 ID1 MAPK1 MAPK1 OTX1 OTX1 WNT5A WNT5A HOXD1 HOXD1 JARID2 JARID2 DVL1 DVL1 STAT3 STAT3 KAT6A KAT6A BMPR2 BMPR2 ONECUT1 ONECUT1 RIF1 RIF1 BMPR1A BMPR1A AKT3 AKT3 ACVR2A ACVR2A AXIN2 AXIN2 WNT7A WNT7A FGFR3 FGFR3 HAND1 HAND1 MAPK12 MAPK12 FZD2 FZD2 ENSCATP00000021128 ENSCATP00000021128 MEIS2 MEIS2 HOXA1 HOXA1 ISL2 ISL2 CTNNB1 CTNNB1 WNT6 WNT6 GSK3B GSK3B LHX5 LHX5 INHBE INHBE IL6ST IL6ST PIK3R2 PIK3R2 HOXB1 HOXB1 ZIC2 ZIC2 PIK3CB PIK3CB SMARCAD1 SMARCAD1 LHX1 LHX1 RAF1 RAF1 WNT11 WNT11 PCGF1 PCGF1 INHBA INHBA SKIL SKIL ZIC3 ZIC3 PAX6 PAX6 LIF LIF PIK3CA PIK3CA CSDE1 CSDE1 PIK3R3 PIK3R3 ISL1 ISL1 LIFR LIFR PIK3R1 PIK3R1 WNT8B WNT8B ENSCATP00000028238 ENSCATP00000028238 WNT9A WNT9A TBX3 TBX3 ACVR2B ACVR2B FGFR2 FGFR2 MYC MYC NODAL NODAL TBX2 TBX2 FGFR4 FGFR4 MAP2K1 MAP2K1 ACVR1B ACVR1B LEFTY2 LEFTY2 AXIN1 AXIN1 AKT2 AKT2 ID4 ID4 POU5F1 POU5F1 DVL3 DVL3 SMAD9 SMAD9 WNT2 WNT2 HESX1 HESX1 SMAD1 SMAD1 NRAS NRAS WNT10A WNT10A SMAD4 SMAD4 JAK1 JAK1 PCGF3 PCGF3 ONECUT3 ONECUT3 ENSCATP00000037667 ENSCATP00000037667 PIK3CD PIK3CD PCGF6 PCGF6 MAPK14 MAPK14 PCGF2 PCGF2 WNT16 WNT16 MYF5 MYF5 BMP4 BMP4 WNT10B WNT10B ZIC1 ZIC1 APC2 APC2 FGFR1 FGFR1 IGF1 IGF1 ACVR1 ACVR1 SMAD5 SMAD5 GRB2 GRB2 TCF7 TCF7 ESRRG ESRRG DVL2 DVL2 FZD3 FZD3 DLX5 DLX5 SETDB1 SETDB1 REST REST WNT9B WNT9B PCGF5 PCGF5 WNT7B WNT7B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000000676Uncharacterized protein. (240 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (445 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
INHBBInhibin subunit beta B. (407 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TCF3BHLH domain-containing protein. (654 aa)
LOC105578089BHLH domain-containing protein. (589 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
ERASES cell expressed Ras. (233 aa)
SOX2SRY-box transcription factor 2. (319 aa)
INHBCInhibin subunit beta C. (352 aa)
LOC105576936Left-right determination factor. (366 aa)
KLF4Kruppel like factor 4. (479 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NEUROG1Neurogenin 1. (237 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
SOX3SRY-box transcription factor 3. (446 aa)
ZFHX3Zinc finger homeobox 3. (3693 aa)
SOX1SRY-box transcription factor 1. (386 aa)
ENSCATP00000008104Homeobox domain-containing protein. (251 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
ESX1ESX homeobox 1. (347 aa)
ENSCATP00000010452Uncharacterized protein. (596 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PRRX1Paired related homeobox 1. (245 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
ONECUT2One cut domain family member. (504 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ESRRBEstrogen related receptor beta. (475 aa)
MEIS1Meis homeobox 1. (469 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (600 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
BMI1RING-type domain-containing protein. (326 aa)
ENSCATP00000015541Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (462 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
HOXD1Homeobox D1. (328 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
STAT3Signal transducer and activator of transcription. (777 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (997 aa)
ONECUT1One cut domain family member. (413 aa)
RIF1Replication timing regulatory factor 1. (2466 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
AXIN2Axin 2. (843 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
ENSCATP00000021128Homeobox domain-containing protein. (188 aa)
MEIS2Meis homeobox 2. (477 aa)
HOXA1Homeobox A1. (335 aa)
ISL2ISL LIM homeobox 2. (359 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa)
LHX5LIM homeobox 5. (402 aa)
INHBEInhibin subunit beta E. (351 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
PIK3R2Uncharacterized protein. (624 aa)
HOXB1Homeobox B1. (301 aa)
ZIC2Zic family member 2. (522 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
SMARCAD1Uncharacterized protein. (1026 aa)
LHX1LIM homeobox 1. (406 aa)
RAF1Uncharacterized protein. (668 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PCGF1Polycomb group ring finger 1. (259 aa)
INHBAInhibin subunit beta A. (426 aa)
SKILSKI like proto-oncogene. (684 aa)
ZIC3Zic family member 3. (466 aa)
PAX6Paired box 6. (493 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ISL1ISL LIM homeobox 1. (349 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ENSCATP00000028238Homeobox domain-containing protein. (277 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (295 aa)
TBX3T-box transcription factor 3. (743 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
NODALNodal growth differentiation factor. (347 aa)
TBX2T-box transcription factor 2. (588 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
LEFTY2Left-right determination factor. (366 aa)
AXIN1Axin 1. (867 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
POU5F1POU domain protein. (360 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HESX1HESX homeobox 1. (185 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
PCGF3Polycomb group ring finger 3. (242 aa)
ONECUT3One cut domain family member. (489 aa)
ENSCATP00000037667Protein kinase domain-containing protein. (365 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PCGF6Polycomb group ring finger 6. (350 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ZIC1Zic family member 1. (447 aa)
APC2APC regulator of WNT signaling pathway 2. (2301 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
IGF1Insulin like growth factor 1. (208 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
SMAD5Mothers against decapentaplegic homolog. (496 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
TCF7Transcription factor 7. (481 aa)
ESRRGEstrogen related receptor gamma. (470 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
DLX5Distal-less homeobox 5. (288 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1272 aa)
RESTRE1 silencing transcription factor. (1095 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
PCGF5Polycomb group ring finger 5. (256 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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