STRINGSTRING
FCER1G FCER1G GP9 GP9 GNAQ GNAQ PTGS1 PTGS1 ADCY1 ADCY1 F2R F2R ADCY4 ADCY4 ACTG1 ACTG1 ADCY3 ADCY3 SYK SYK TBXAS1 TBXAS1 LOC105585318 LOC105585318 GP1BB GP1BB PLA2G4C PLA2G4C STIM1 STIM1 SRC SRC LCP2 LCP2 VWF VWF RHOA RHOA P2RY1 P2RY1 ACTRT1 ACTRT1 AKT1 AKT1 MAPK13 MAPK13 ACTL7A ACTL7A P2RY12 P2RY12 ADCY7 ADCY7 ACTL7B ACTL7B DHRSX DHRSX PLA2G4A PLA2G4A ARHGAP35 ARHGAP35 COL1A1 COL1A1 MAPK11 MAPK11 GNA13 GNA13 VAMP8 VAMP8 PLA2G4E PLA2G4E FGA FGA MAPK3 MAPK3 FCGR2B FCGR2B LYN LYN ADCY9 ADCY9 GNAI3 GNAI3 PPP1CA PPP1CA ACTB ACTB RDH13 RDH13 COL3A1 COL3A1 TLN1 TLN1 ARHGEF1 ARHGEF1 ADCY6 ADCY6 ROCK1 ROCK1 MAPK1 MAPK1 PLCB3 PLCB3 COL1A2 COL1A2 MYL12B MYL12B ITGB3 ITGB3 PLA2G4B PLA2G4B PRKCI PRKCI GP6 GP6 MYLK3 MYLK3 GNAI1 GNAI1 AKT3 AKT3 JMJD7 JMJD7 ENSCATP00000019657 ENSCATP00000019657 PTRHD1 PTRHD1 FCGR2A FCGR2A PIK3R6 PIK3R6 PLCG2 PLCG2 ADCY2 ADCY2 BTK BTK MAPK12 MAPK12 ADCY8 ADCY8 ITGA2B ITGA2B ENSCATP00000023132 ENSCATP00000023132 ENSCATP00000023365 ENSCATP00000023365 FYN FYN FGB FGB PIK3R2 PIK3R2 PIK3CB PIK3CB ACTL8 ACTL8 ZNF408 ZNF408 ARHGEF12 ARHGEF12 FERMT3 FERMT3 PRKCZ PRKCZ PRKG2 PRKG2 ENSCATP00000026377 ENSCATP00000026377 PLA2G4F PLA2G4F MYLK4 MYLK4 ITGA2 ITGA2 ADCY5 ADCY5 MYLK2 MYLK2 PLCB4 PLCB4 PIK3CA PIK3CA PIK3R3 PIK3R3 PLCB2 PLCB2 TBXA2R TBXA2R PIK3R1 PIK3R1 PRKG1 PRKG1 SRMS SRMS PPP1CB PPP1CB GUCY1A2 GUCY1A2 ITPR3 ITPR3 ITPR2 ITPR2 F2 F2 PPP1R12A PPP1R12A ITGB1 ITGB1 FGG FGG GNAS GNAS AKT2 AKT2 PTK6 PTK6 LOC105579900 LOC105579900 PPP1CC PPP1CC RDH14 RDH14 SSPO SSPO TLN2 TLN2 PIK3CG PIK3CG GUCY1A1 GUCY1A1 PLA2G4D PLA2G4D NOS3 NOS3 APBB1IP APBB1IP SNAP23 SNAP23 MYL12A MYL12A ITPR1 ITPR1 MYLK MYLK PIK3CD PIK3CD P2RX1 P2RX1 MAPK14 MAPK14 GP1BA GP1BA PIK3R5 PIK3R5 PRKACB PRKACB ENSCATP00000039367 ENSCATP00000039367 F2RL3 F2RL3 RASGRP2 RASGRP2 VASP VASP LOC105573641 LOC105573641 ROCK2 ROCK2 GNAI2 GNAI2 RASGRP1 RASGRP1 PRKACA PRKACA RAP1B RAP1B PTGIR PTGIR ORAI1 ORAI1 GUCY1B1 GUCY1B1 RAP1A RAP1A PLCB1 PLCB1 RHOC RHOC LRRC15 LRRC15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FCER1GFc fragment of IgE receptor Ig. (111 aa)
GP9Glycoprotein IX platelet. (177 aa)
GNAQUncharacterized protein. (359 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ACTG1Actin gamma 1. (377 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa)
LOC105585318Uncharacterized protein. (246 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
PLA2G4CPhospholipase A2 group IVC. (531 aa)
STIM1Stromal interaction molecule 1. (784 aa)
SRCTyrosine-protein kinase. (644 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
VWFVon Willebrand factor. (2812 aa)
RHOARas homolog family member A. (193 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
DHRSXDehydrogenase/reductase X-linked. (330 aa)
PLA2G4APhospholipase A2. (749 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
GNA13G protein subunit alpha 13. (377 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
PLA2G4EPhospholipase A2. (869 aa)
FGAFibrinogen alpha chain. (863 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
FCGR2BUncharacterized protein. (313 aa)
LYNTyrosine-protein kinase. (507 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
ACTBUncharacterized protein. (375 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (323 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
TLN1Talin 1. (2546 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1337 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
MYL12BMyosin light chain 12B. (172 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PLA2G4BPhospholipase A2. (781 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
GP6Glycoprotein VI platelet. (563 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
GNAI1G protein subunit alpha i1. (330 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
JMJD7Jumonji domain containing 7. (316 aa)
ENSCATP00000019657Uncharacterized protein; Belongs to the actin family. (368 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (139 aa)
FCGR2AUncharacterized protein. (317 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
BTKTyrosine-protein kinase. (659 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
ENSCATP00000023132Uncharacterized protein. (138 aa)
ENSCATP00000023365Uncharacterized protein. (143 aa)
FYNTyrosine-protein kinase. (537 aa)
FGBFibrinogen beta chain. (491 aa)
PIK3R2Uncharacterized protein. (624 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ACTL8Actin like 8; Belongs to the actin family. (386 aa)
ZNF408Zinc finger protein 408. (719 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
FERMT3Fermitin family member 3. (663 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ENSCATP00000026377Uncharacterized protein. (170 aa)
PLA2G4FPhospholipase A2. (849 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
TBXA2RThromboxane A2 receptor. (406 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
SRMSTyrosine-protein kinase. (492 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2. (419 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2568 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
FGGFibrinogen gamma chain. (453 aa)
GNASGNAS complex locus. (1028 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PTK6Tyrosine-protein kinase. (507 aa)
LOC105579900Uncharacterized protein. (319 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
SSPOSCO-spondin. (5143 aa)
TLN2Talin 2. (2542 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PLA2G4DPhospholipase A2. (817 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (665 aa)
SNAP23Synaptosome associated protein 23. (211 aa)
MYL12AMyosin light chain 12A. (177 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2745 aa)
MYLKMyosin light chain kinase. (1914 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (638 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (880 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSCATP00000039367Uncharacterized protein. (360 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
RASGRP2RAS guanyl releasing protein 2. (610 aa)
VASPVasodilator stimulated phosphoprotein. (431 aa)
LOC105573641Uncharacterized protein; Belongs to the actin family. (323 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
GNAI2G protein subunit alpha i2. (355 aa)
RASGRP1RAS guanyl releasing protein 1. (837 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
RAP1BUncharacterized protein. (184 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (298 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
RHOCRas homolog family member C. (193 aa)
LRRC15Leucine rich repeat containing 15. (584 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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