STRINGSTRING
WAS WAS ARPC4 ARPC4 DOCK1 DOCK1 PRKCD PRKCD PLA2G6 PLA2G6 PLCG1 PLCG1 LIMK1 LIMK1 CFL1 CFL1 LAT LAT CDC42 CDC42 HCK HCK PRKCG PRKCG GAB2 GAB2 PIP5K1C PIP5K1C PLCG2 PLCG2 PLD1 PLD1 LOC105571657 LOC105571657 FCGR2A FCGR2A LOC105589237 LOC105589237 ENSCATP00000019774 ENSCATP00000019774 JMJD7 JMJD7 SCIN SCIN AKT3 AKT3 PIP5K1A PIP5K1A LOC105571773 LOC105571773 VAV1 VAV1 PLA2G4B PLA2G4B ARPC2 ARPC2 ENSCATP00000017084 ENSCATP00000017084 PAK1 PAK1 MAPK1 MAPK1 ENSCATP00000015421 ENSCATP00000015421 ENSCATP00000015134 ENSCATP00000015134 ASAP1 ASAP1 ASAP3 ASAP3 PRKCA PRKCA GAB4 GAB4 RPS6KB2 RPS6KB2 PIP5K1B PIP5K1B ENSCATP00000013162 ENSCATP00000013162 ENSCATP00000012908 ENSCATP00000012908 RAC1 RAC1 LYN LYN FCGR2B FCGR2B MAPK3 MAPK3 LOC105575920 LOC105575920 PLA2G4E PLA2G4E LIMK2 LIMK2 ENSCATP00000010452 ENSCATP00000010452 PLPP1 PLPP1 LOC105577130 LOC105577130 WASF1 WASF1 RPS6KB1 RPS6KB1 ENSCATP00000009482 ENSCATP00000009482 WASF2 WASF2 PRKCB PRKCB PLA2G4A PLA2G4A PTPRC PTPRC LOC105600295 LOC105600295 ENSCATP00000007240 ENSCATP00000007240 AMPH AMPH ENSCATP00000006802 ENSCATP00000006802 ENSCATP00000006715 ENSCATP00000006715 AKT1 AKT1 LOC105577155 LOC105577155 LOC105574050 LOC105574050 MYO10 MYO10 ENSCATP00000005099 ENSCATP00000005099 ENSCATP00000005024 ENSCATP00000005024 ENSCATP00000004469 ENSCATP00000004469 LOC105571986 LOC105571986 INPP5D INPP5D PLA2G4C PLA2G4C ARF6 ARF6 VAV3 VAV3 GOLGA2 GOLGA2 MARCKS MARCKS GSN GSN SYK SYK ENSCATP00000001309 ENSCATP00000001309 LOC105574081 LOC105574081 PLPP3 PLPP3 NCF1 NCF1 LOC105574253 LOC105574253 PIK3R2 PIK3R2 PIK3CB PIK3CB BIN1 BIN1 RAF1 RAF1 ASAP2 ASAP2 ENSCATP00000025434 ENSCATP00000025434 VAV2 VAV2 PLA2G4F PLA2G4F ENSCATP00000026691 ENSCATP00000026691 LOC105592899 LOC105592899 PIK3CA PIK3CA PIK3R3 PIK3R3 ARPC1B ARPC1B PIK3R1 PIK3R1 ENSCATP00000027915 ENSCATP00000027915 ARPC5L ARPC5L WASF3 WASF3 ARPC5 ARPC5 ENSCATP00000029599 ENSCATP00000029599 MAP2K1 MAP2K1 INPPL1 INPPL1 DNM2 DNM2 PLD2 PLD2 AKT2 AKT2 LOC105594104 LOC105594104 ENSCATP00000032953 ENSCATP00000032953 SPHK1 SPHK1 CRKL CRKL ARPC3 ARPC3 RAC2 RAC2 SPHK2 SPHK2 PLA2G4D PLA2G4D ENSCATP00000035309 ENSCATP00000035309 PRKCE PRKCE ENSCATP00000037667 ENSCATP00000037667 PIK3CD PIK3CD CRK CRK VASP VASP PLPP2 PLPP2 MARCKSL1 MARCKSL1 ENSCATP00000042801 ENSCATP00000042801 CCDC125 CCDC125 ENSCATP00000043705 ENSCATP00000043705
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WASWASP actin nucleation promoting factor. (503 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (290 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PLA2G6Phospholipase A2 group VI. (784 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LIMK1LIM domain kinase 1. (672 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (197 aa)
LATLinker for activation of T cells. (270 aa)
CDC42Uncharacterized protein. (191 aa)
HCKTyrosine-protein kinase. (504 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GAB2GRB2 associated binding protein 2. (676 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (700 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
PLD1Phospholipase. (1067 aa)
LOC105571657ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (187 aa)
FCGR2AUncharacterized protein. (317 aa)
LOC105589237Low affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor (By similarity). Binds IgG1 and IgG2. (336 aa)
ENSCATP00000019774Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (139 aa)
JMJD7Jumonji domain containing 7. (316 aa)
SCINScinderin. (706 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
LOC105571773Uncharacterized protein. (676 aa)
VAV1Vav guanine nucleotide exchange factor 1. (856 aa)
PLA2G4BPhospholipase A2. (781 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
ENSCATP00000017084Uncharacterized protein. (185 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSCATP00000015421Ig-like domain-containing protein. (140 aa)
ENSCATP00000015134Ig-like domain-containing protein. (173 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1129 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (903 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
GAB4GRB2 associated binding protein family member 4. (536 aa)
RPS6KB2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa)
ENSCATP00000013162Uncharacterized protein. (173 aa)
ENSCATP00000012908Ig-like domain-containing protein. (144 aa)
RAC1Uncharacterized protein. (212 aa)
LYNTyrosine-protein kinase. (507 aa)
FCGR2BUncharacterized protein. (313 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
LOC105575920Ig-like domain-containing protein. (140 aa)
PLA2G4EPhospholipase A2. (869 aa)
LIMK2LIM domain kinase 2. (638 aa)
ENSCATP00000010452Uncharacterized protein. (596 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
LOC105577130Ig-like domain-containing protein. (133 aa)
WASF1WASP family member 1. (559 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ENSCATP00000009482Ig-like domain-containing protein. (139 aa)
WASF2WASP family member 2. (498 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PLA2G4APhospholipase A2. (749 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
LOC105600295Uncharacterized protein. (647 aa)
ENSCATP00000007240PIPK domain-containing protein. (467 aa)
AMPHAmphiphysin. (694 aa)
ENSCATP00000006802Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
ENSCATP00000006715Ig-like domain-containing protein. (140 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC105577155Uncharacterized protein. (380 aa)
LOC105574050Ig-like domain-containing protein. (138 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2035 aa)
ENSCATP00000005099Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (161 aa)
ENSCATP00000005024Ig-like domain-containing protein. (150 aa)
ENSCATP00000004469Uncharacterized protein. (191 aa)
LOC105571986Uncharacterized protein. (189 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1184 aa)
PLA2G4CPhospholipase A2 group IVC. (531 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
GOLGA2Golgin A2. (1005 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (331 aa)
GSNGelsolin. (809 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
ENSCATP00000001309Uncharacterized protein. (109 aa)
LOC105574081Ig-like domain-containing protein. (132 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
NCF1Neutrophil cytosolic factor 1. (423 aa)
LOC105574253Uncharacterized protein. (443 aa)
PIK3R2Uncharacterized protein. (624 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
BIN1Bridging integrator 1. (608 aa)
RAF1Uncharacterized protein. (668 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
ENSCATP00000025434Uncharacterized protein. (92 aa)
VAV2Vav guanine nucleotide exchange factor 2. (868 aa)
PLA2G4FPhospholipase A2. (849 aa)
ENSCATP00000026691ADF-H domain-containing protein. (126 aa)
LOC105592899Uncharacterized protein. (357 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCATP00000027915Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (143 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa)
WASF3WASP family member 3. (502 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSCATP00000029599WD_REPEATS_REGION domain-containing protein. (334 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
PLD2Phospholipase. (933 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC105594104Uncharacterized protein. (612 aa)
ENSCATP00000032953PIPK domain-containing protein. (487 aa)
SPHK1Sphingosine kinase 1. (470 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (182 aa)
RAC2Rac family small GTPase 2. (192 aa)
SPHK2Sphingosine kinase 2. (653 aa)
PLA2G4DPhospholipase A2. (817 aa)
ENSCATP00000035309Uncharacterized protein. (622 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
ENSCATP00000037667Protein kinase domain-containing protein. (365 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
VASPVasodilator stimulated phosphoprotein. (431 aa)
PLPP2Phospholipid phosphatase 2. (303 aa)
MARCKSL1MARCKS like 1. (195 aa)
ENSCATP00000042801Uncharacterized protein. (136 aa)
CCDC125Coiled-coil domain containing 125. (495 aa)
ENSCATP00000043705Uncharacterized protein. (238 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (28%) [HD]