STRINGSTRING
KRT32 KRT32 GNAQ GNAQ EBAG9 EBAG9 KRT13 KRT13 ADCY1 ADCY1 ADCY4 ADCY4 ATF2 ATF2 ENSCATP00000001293 ENSCATP00000001293 ADCY3 ADCY3 KRT18 KRT18 LOC105576459 LOC105576459 ENSCATP00000002884 ENSCATP00000002884 LOC105585318 LOC105585318 KCNJ5 KCNJ5 KRT28 KRT28 LOC105579629 LOC105579629 LOC105579060 LOC105579060 CEP152 CEP152 GRM1 GRM1 MMP2 MMP2 ENSCATP00000004013 ENSCATP00000004013 SOS1 SOS1 SRC SRC KCNJ3 KCNJ3 ERAS ERAS KRT27 KRT27 SP1 SP1 HSP90B1 HSP90B1 AKT1 AKT1 CALML3 CALML3 ENSCATP00000006855 ENSCATP00000006855 PVALEF PVALEF ENSCATP00000007407 ENSCATP00000007407 HSPA1L HSPA1L ENSCATP00000007490 ENSCATP00000007490 ADCY7 ADCY7 ENSCATP00000007830 ENSCATP00000007830 FKBP5 FKBP5 GABBR1 GABBR1 KCNJ9 KCNJ9 PGR PGR ENSCATP00000010452 ENSCATP00000010452 OPRM1 OPRM1 GABBR2 GABBR2 MMP9 MMP9 CREB3L4 CREB3L4 MAPK3 MAPK3 KRAS KRAS ESR1 ESR1 CTSD CTSD ENSCATP00000012196 ENSCATP00000012196 ATF4 ATF4 ADCY9 ADCY9 ATF6B ATF6B MAP2K2 MAP2K2 GNAI3 GNAI3 HSPA6 HSPA6 HRAS HRAS CCDC170 CCDC170 ADCY6 ADCY6 KRT19 KRT19 MAPK1 MAPK1 PLCB3 PLCB3 KRT25 KRT25 KRT26 KRT26 GNAI1 GNAI1 ENSCATP00000019466 ENSCATP00000019466 AKT3 AKT3 PTRHD1 PTRHD1 CALM2 CALM2 ADCY2 ADCY2 ADCY8 ADCY8 CREB3L2 CREB3L2 ENSCATP00000022027 ENSCATP00000022027 KRT40 KRT40 PRKCD PRKCD ENSCATP00000022722 ENSCATP00000022722 FKBP4 FKBP4 HSP90AB1 HSP90AB1 PIK3R2 PIK3R2 PIK3CB PIK3CB LOC105585293 LOC105585293 ENSCATP00000024311 ENSCATP00000024311 RAF1 RAF1 NCOA1 NCOA1 HSPA8 HSPA8 NCOA3 NCOA3 CREB3L1 CREB3L1 LOC105571822 LOC105571822 ESR2 ESR2 CALM3 CALM3 ADCY5 ADCY5 PLCB4 PLCB4 KRT39 KRT39 PIK3CA PIK3CA SHC1 SHC1 CSDE1 CSDE1 PIK3R3 PIK3R3 CREB1 CREB1 KCNJ6 KCNJ6 PLCB2 PLCB2 PIK3R1 PIK3R1 ENSCATP00000028019 ENSCATP00000028019 ITPR3 ITPR3 ITPR2 ITPR2 HSPA2 HSPA2 CREB3 CREB3 MAP2K1 MAP2K1 KRT9 KRT9 ENSCATP00000031565 ENSCATP00000031565 GNAS GNAS AKT2 AKT2 ENSCATP00000032242 ENSCATP00000032242 NCOA2 NCOA2 CREB5 CREB5 KRT33A KRT33A KRT12 KRT12 CALM1 CALM1 EGFR EGFR KRT20 KRT20 SHC4 SHC4 CALML4 CALML4 KRT33B KRT33B KRT24 KRT24 KRT23 KRT23 CREB3L3 CREB3L3 NOS3 NOS3 NRAS NRAS POMC POMC KRT34 KRT34 KRT14 KRT14 KRT38 KRT38 ITPR1 ITPR1 ENSCATP00000037667 ENSCATP00000037667 ENSCATP00000038085 ENSCATP00000038085 PIK3CD PIK3CD HSP90AA1 HSP90AA1 TFF1 TFF1 PRKACB PRKACB SOS2 SOS2 ENSCATP00000040020 ENSCATP00000040020 TGFA TGFA ENSCATP00000041326 ENSCATP00000041326 SHC3 SHC3 GNAI2 GNAI2 KRT37 KRT37 GRB2 GRB2 KRT15 KRT15 BCL2 BCL2 KRT10 KRT10 LOC105577185 LOC105577185 KRT35 KRT35 GNAO1 GNAO1 ENSCATP00000043586 ENSCATP00000043586 KRT31 KRT31 PRKACA PRKACA ENSCATP00000044017 ENSCATP00000044017 KRT36 KRT36 RARA RARA HBEGF HBEGF FOS FOS CALML6 CALML6 PLCB1 PLCB1 GPER1 GPER1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRT32Keratin 32; Belongs to the intermediate filament family. (448 aa)
GNAQUncharacterized protein. (359 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (258 aa)
KRT13IF rod domain-containing protein; Belongs to the intermediate filament family. (450 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSCATP00000001293Uncharacterized protein; Belongs to the heat shock protein 70 family. (604 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
KRT18IF rod domain-containing protein; Belongs to the intermediate filament family. (538 aa)
LOC105576459IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa)
ENSCATP00000002884HATPase_c domain-containing protein. (680 aa)
LOC105585318Uncharacterized protein. (246 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
KRT28Keratin 28; Belongs to the intermediate filament family. (464 aa)
LOC105579629IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa)
LOC105579060HATPase_c domain-containing protein. (641 aa)
CEP152Centrosomal protein 152. (1706 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
ENSCATP00000004013Uncharacterized protein. (711 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SRCTyrosine-protein kinase. (644 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
ERASES cell expressed Ras. (233 aa)
KRT27Keratin 27; Belongs to the intermediate filament family. (459 aa)
SP1Sp1 transcription factor. (786 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ENSCATP00000006855Uncharacterized protein. (519 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
ENSCATP00000007407PID domain-containing protein. (502 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
ENSCATP00000007490IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
ENSCATP00000007830Uncharacterized protein. (436 aa)
FKBP5Peptidylprolyl isomerase. (452 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1007 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
PGRProgesterone receptor. (933 aa)
ENSCATP00000010452Uncharacterized protein. (596 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (460 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
CTSDCathepsin D; Belongs to the peptidase A1 family. (603 aa)
ENSCATP00000012196Uncharacterized protein. (127 aa)
ATF4Activating transcription factor 4. (351 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
GNAI3G protein subunit alpha i3. (354 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (605 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CCDC170Coiled-coil domain containing 170. (709 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (396 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
KRT25Keratin 25; Belongs to the intermediate filament family. (410 aa)
KRT26Keratin 26; Belongs to the intermediate filament family. (468 aa)
GNAI1G protein subunit alpha i1. (330 aa)
ENSCATP00000019466Uncharacterized protein; Belongs to the heat shock protein 70 family. (621 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (139 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ENSCATP00000022027Uncharacterized protein; Belongs to the heat shock protein 70 family. (594 aa)
KRT40Keratin 40; Belongs to the intermediate filament family. (431 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ENSCATP00000022722Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
FKBP4Peptidylprolyl isomerase. (459 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
PIK3R2Uncharacterized protein. (624 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
LOC105585293Uncharacterized protein. (290 aa)
ENSCATP00000024311IF rod domain-containing protein; Belongs to the intermediate filament family. (151 aa)
RAF1Uncharacterized protein. (668 aa)
NCOA1Nuclear receptor coactivator. (1515 aa)
HSPA8Uncharacterized protein. (129 aa)
NCOA3Nuclear receptor coactivator. (1428 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
LOC105571822Uncharacterized protein; Belongs to the heat shock protein 70 family. (534 aa)
ESR2Estrogen receptor 2. (530 aa)
CALM3Calmodulin 3. (149 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
KRT39Keratin 39; Belongs to the intermediate filament family. (491 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
SHC1SHC adaptor protein 1. (584 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCATP00000028019HATPase_c domain-containing protein. (647 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2568 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa)
KRT9Keratin 9; Belongs to the intermediate filament family. (367 aa)
ENSCATP00000031565Uncharacterized protein. (357 aa)
GNASGNAS complex locus. (1028 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSCATP00000032242Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
NCOA2Nuclear receptor coactivator. (1468 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
KRT33AKeratin 33A; Belongs to the intermediate filament family. (404 aa)
KRT12Keratin 12; Belongs to the intermediate filament family. (495 aa)
CALM1Calmodulin 1. (149 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
KRT20Keratin 20; Belongs to the intermediate filament family. (424 aa)
SHC4SHC adaptor protein 4. (630 aa)
CALML4Calmodulin like 4. (193 aa)
KRT33BKeratin 33B; Belongs to the intermediate filament family. (404 aa)
KRT24Keratin 24; Belongs to the intermediate filament family. (525 aa)
KRT23Keratin 23; Belongs to the intermediate filament family. (422 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (461 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
POMCProopiomelanocortin. (265 aa)
KRT34Keratin 34; Belongs to the intermediate filament family. (436 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (504 aa)
KRT38Keratin 38; Belongs to the intermediate filament family. (452 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2745 aa)
ENSCATP00000037667Protein kinase domain-containing protein. (365 aa)
ENSCATP00000038085IF rod domain-containing protein; Belongs to the intermediate filament family. (382 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (831 aa)
TFF1Trefoil factor 1. (88 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa)
ENSCATP00000040020Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
TGFATransforming growth factor alpha. (166 aa)
ENSCATP00000041326IF rod domain-containing protein; Belongs to the intermediate filament family. (402 aa)
SHC3SHC adaptor protein 3. (598 aa)
GNAI2G protein subunit alpha i2. (355 aa)
KRT37Keratin 37; Belongs to the intermediate filament family. (449 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (456 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
KRT10Keratin 10; Belongs to the intermediate filament family. (564 aa)
LOC105577185Uncharacterized protein. (133 aa)
KRT35Keratin 35; Belongs to the intermediate filament family. (455 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ENSCATP00000043586Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
KRT31IF rod domain-containing protein; Belongs to the intermediate filament family. (416 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
ENSCATP00000044017IF rod domain-containing protein; Belongs to the intermediate filament family. (379 aa)
KRT36Keratin 36; Belongs to the intermediate filament family. (467 aa)
RARARetinoic acid receptor alpha. (478 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CALML6Calmodulin like 6. (181 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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