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GNAQ GNAQ KCNN4 KCNN4 KCNJ5 KCNJ5 KCNJ3 KCNJ3 ERAS ERAS ARR3 ARR3 AKT1 AKT1 GNRH2 GNRH2 KCNJ11 KCNJ11 CACNA1F CACNA1F GABBR1 GABBR1 PRKCB PRKCB KCNJ9 KCNJ9 CACNA1D CACNA1D ENSCATP00000010452 ENSCATP00000010452 TRPC5 TRPC5 GABBR2 GABBR2 MAPK3 MAPK3 KCNN2 KCNN2 KRAS KRAS MAP2K2 MAP2K2 PRKCA PRKCA HRAS HRAS MAPK1 MAPK1 PLCB3 PLCB3 KISS1R KISS1R AKT3 AKT3 HCN3 HCN3 TRPC1 TRPC1 PRKCG PRKCG PIK3R2 PIK3R2 PIK3CB PIK3CB RAF1 RAF1 SPP1 SPP1 ESR2 ESR2 KCNN3 KCNN3 PLCB4 PLCB4 KISS1 KISS1 PIK3CA PIK3CA CSDE1 CSDE1 PIK3R3 PIK3R3 KCNJ6 KCNJ6 PLCB2 PLCB2 PIK3R1 PIK3R1 CGA CGA PIK3CD PIK3CD LHB LHB CACNA1S CACNA1S HCN2 HCN2 CACNA1I CACNA1I KCNN1 KCNN1 CACNA1C CACNA1C HCN1 HCN1 LOC105595270 LOC105595270 PLCB1 PLCB1 TRPC4 TRPC4 GPER1 GPER1 CACNA1H CACNA1H ITPR3 ITPR3 ITPR2 ITPR2 MAP2K1 MAP2K1 GNA11 GNA11 AKT2 AKT2 CACNA1G CACNA1G ARRB1 ARRB1 NRAS NRAS ITPR1 ITPR1 ENSCATP00000037667 ENSCATP00000037667 GNRH1 GNRH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNAQUncharacterized protein. (359 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
ERASES cell expressed Ras. (233 aa)
ARR3Arrestin 3. (388 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNRH2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (121 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1007 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ENSCATP00000010452Uncharacterized protein. (596 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (847 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
KISS1RKISS1 receptor. (398 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (777 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PIK3R2Uncharacterized protein. (624 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
RAF1Uncharacterized protein. (668 aa)
SPP1Secreted phosphoprotein 1. (324 aa)
ESR2Estrogen receptor 2. (530 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (748 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
KISS1KiSS-1 metastasis suppressor. (146 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LHBCys_knot domain-containing protein. (141 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (833 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2227 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (885 aa)
LOC105595270Cys_knot domain-containing protein. (167 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2313 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2568 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa)
GNA11G protein subunit alpha 11. (394 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
ARRB1Arrestin beta 1. (418 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2745 aa)
ENSCATP00000037667Protein kinase domain-containing protein. (365 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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