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| | ENSCATP00000036475 | Uncharacterized protein. (59 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (550 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | PDIA3 | Protein disulfide isomerase family A member 3. (451 aa) |
| | ENSCATP00000035075 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa) |
| | TRIM34 | Uncharacterized protein. (427 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | ENSCATP00000034500 | Uncharacterized protein. (464 aa) |
| | IRF3 | Interferon regulatory factor 3. (422 aa) |
| | CALML4 | Calmodulin like 4. (193 aa) |
| | ENSCATP00000034214 | Ig-like domain-containing protein; Belongs to the MHC class I family. (329 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | TRIM6 | Tripartite motif containing 6. (559 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | TRADD | TNFRSF1A associated via death domain. (308 aa) |
| | ENSCATP00000012040 | IGc1 domain-containing protein; Belongs to the MHC class I family. (392 aa) |
| | APOBEC3H | Apolipoprotein B mRNA editing enzyme catalytic subunit 3H. (199 aa) |
| | ENSCATP00000012291 | Uncharacterized protein; Belongs to the cyclin family. (349 aa) |
| | RAC1 | Uncharacterized protein. (212 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | ENSCATP00000012901 | MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (217 aa) |
| | TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa) |
| | ENSCATP00000012999 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa) |
| | ENSCATP00000013364 | Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa) |
| | CDC25C | Cell division cycle 25C. (471 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | RPS6KB2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1512 aa) |
| | AP1G2 | AP-1 complex subunit gamma. (785 aa) |
| | BID | BH3 interacting domain death agonist. (244 aa) |
| | ELOB | Elongin B. (167 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | ENSCATP00000018990 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNAI1 | G protein subunit alpha i1. (330 aa) |
| | CALR | Calreticulin. (389 aa) |
| | ENSCATP00000019442 | Uncharacterized protein. (368 aa) |
| | ENSCATP00000019483 | MHC_I-like_Ag-recog domain-containing protein. (80 aa) |
| | LOC105572981 | Uncharacterized protein. (132 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | LOC105571657 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (187 aa) |
| | ENSCATP00000020004 | Uncharacterized protein; Belongs to the SKP1 family. (198 aa) |
| | CALM2 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (808 aa) |
| | ENSCATP00000020536 | MHC_I-like_Ag-recog domain-containing protein. (176 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (961 aa) |
| | TRIM5 | Tripartite motif-containing 5 alpha isoform. (497 aa) |
| | CFL1 | Cofilin 1; Belongs to the actin-binding proteins ADF family. (197 aa) |
| | LIMK1 | LIM domain kinase 1. (672 aa) |
| | ELOC | Elongin C. (112 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | CUL5 | Cullin 5; Belongs to the cullin family. (784 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | ENSCATP00000023705 | RING-type domain-containing protein. (100 aa) |
| | PIK3R2 | Uncharacterized protein. (624 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | ENSCATP00000024481 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) |
| | ENSCATP00000024633 | MHC_I-like_Ag-recog domain-containing protein. (147 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | LOC105601524 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | ENSCATP00000026030 | G protein gamma domain-containing protein. (59 aa) |
| | CALM3 | Calmodulin 3. (149 aa) |
| | ENSCATP00000026691 | ADF-H domain-containing protein. (126 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (515 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (580 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (462 aa) |
| | TRAC | T cell receptor alpha constant. (110 aa) |
| | LOC105576705 | Ig-like domain-containing protein; Belongs to the MHC class I family. (368 aa) |
| | ENSCATP00000028696 | Ig-like domain-containing protein. (133 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2568 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1064 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (462 aa) |
| | ENSCATP00000030160 | Ig-like domain-containing protein; Belongs to the MHC class I family. (349 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | PPP1R14B | Uncharacterized protein. (207 aa) |
| | GNA11 | G protein subunit alpha 11. (394 aa) |
| | ENSCATP00000030836 | Uncharacterized protein. (149 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | PLVAP | Plasmalemma vesicle associated protein. (442 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | TAP2 | Transporter 2, ATP binding cassette subfamily B member. (711 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (744 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | ENSCATP00000032242 | Uncharacterized protein; Belongs to the calmodulin family. (128 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa) |
| | ENSCATP00000032552 | Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (109 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3073 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | CALM1 | Calmodulin 1. (149 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (438 aa) |
| | ENSCATP00000033138 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | ENSCATP00000033254 | Ig-like domain-containing protein; Belongs to the MHC class I family. (339 aa) |
| | ENSCATP00000033319 | Uncharacterized protein. (66 aa) |
| | ENSCATP00000004066 | Uncharacterized protein. (189 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | ENSCATP00000004605 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1068 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | ENSCATP00000006421 | Protein kinase domain-containing protein. (297 aa) |
| | LOC105584562 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa) |
| | LOC105588083 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CHEK1 | Checkpoint kinase 1. (493 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (637 aa) |
| | GNB5 | G protein subunit beta 5. (409 aa) |
| | LOC105589984 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PVALEF | Parvalbumin like EF-hand containing. (133 aa) |
| | CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | LOC105581531 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | AP1M2 | AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (419 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1357 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | TAPBP | TAP binding protein. (504 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | ENSCATP00000009380 | Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa) |
| | LOC105573008 | Uncharacterized protein. (79 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (973 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | ENSCATP00000010452 | Uncharacterized protein. (596 aa) |
| | LIMK2 | LIM domain kinase 2. (638 aa) |
| | RAC3 | Rac family small GTPase 3. (205 aa) |
| | LOC105576712 | Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (913 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | CD247 | CD247 molecule. (165 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PXN | Paxillin. (1082 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1143 aa) |
| | CCDC125 | Coiled-coil domain containing 125. (495 aa) |
| | ENSCATP00000043586 | Uncharacterized protein; Belongs to the calmodulin family. (128 aa) |
| | GNAO1 | G protein subunit alpha o1. (354 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (721 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (309 aa) |
| | ENSCATP00000003553 | MHC_I-like_Ag-recog domain-containing protein. (170 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (586 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (356 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (474 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | TRIM22 | TRIM22. (498 aa) |
| | ENSCATP00000041581 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | APOBEC3C | Apolipoprotein B mRNA editing enzyme catalytic subunit 3C. (190 aa) |
| | LOC105571593 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (921 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) |
| | ENSCATP00000040020 | Uncharacterized protein; Belongs to the calmodulin family. (91 aa) |
| | AP1M1 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa) |
| | TRBV11-1 | T cell receptor beta variable 11-1. (142 aa) |
| | BST2 | Bone marrow stromal cell antigen 2. (182 aa) |
| | AP1B1 | AP complex subunit beta. (949 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | TRBV10-1 | T cell receptor beta variable 10-1(gene/pseudogene). (131 aa) |
| | CD3G | CD3g molecule. (181 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (597 aa) |
| | CCDC194 | Coiled-coil domain containing 194. (126 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ENSCATP00000038494 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa) |
| | ENSCATP00000038453 | Uncharacterized protein; Belongs to the peptidase C14A family. (262 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ENSCATP00000037667 | Protein kinase domain-containing protein. (365 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2745 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | ENSCATP00000000152 | Uncharacterized protein. (64 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (563 aa) |
| | GNAQ | Uncharacterized protein. (359 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | ENSCATP00000001050 | G protein gamma domain-containing protein. (63 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC105595720 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCATP00000001452 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (98 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (522 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | ENSCATP00000001579 | Uncharacterized protein. (97 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | HLA-F | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (439 aa) |
| | LOC105576630 | Ig-like domain-containing protein; Belongs to the MHC class I family. (403 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | ENSCATP00000002136 | Ig-like domain-containing protein; Belongs to the MHC class I family. (331 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (408 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (517 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
