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| | ENSCATP00000000560 | C2 tensin-type domain-containing protein. (165 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (927 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1051 aa) |
| | GPSM3 | G protein signaling modulator 3. (160 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (159 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (331 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (213 aa) |
| | SOX4 | Transcription factor SOX. (475 aa) |
| | CEP152 | Centrosomal protein 152. (1706 aa) |
| | TPTE2 | Uncharacterized protein. (550 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | ENSCATP00000004066 | Uncharacterized protein. (189 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (547 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (172 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1127 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1024 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1314 aa) |
| | ENSCATP00000007407 | PID domain-containing protein. (502 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | NOTCH1 | Notch receptor 1. (2547 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1399 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | ENSCATP00000010452 | Uncharacterized protein. (596 aa) |
| | TNN | Tenascin N. (1269 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1349 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (862 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | EZR | Ezrin. (603 aa) |
| | EFNA3 | Ephrin A3; Belongs to the ephrin family. (238 aa) |
| | APC | APC regulator of WNT signaling pathway. (2861 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | CDC25C | Cell division cycle 25C. (471 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1632 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa) |
| | ZFPM2 | Zinc finger protein, FOG family member 2. (992 aa) |
| | BMI1 | RING-type domain-containing protein. (326 aa) |
| | FSCN2 | Fascin. (492 aa) |
| | ROCK1 | Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1337 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | HOXD10 | Homeobox D10. (340 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (206 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | STAT3 | Signal transducer and activator of transcription. (777 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (350 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (997 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | CDC25B | Cell division cycle 25B. (580 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (809 aa) |
| | ENSCATP00000020093 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (433 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (338 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa) |
| | ENSCATP00000020494 | Uncharacterized protein. (408 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) |
| | EFNA2 | Ephrin A2; Belongs to the ephrin family. (213 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1129 aa) |
| | PDCD4 | Programmed cell death 4. (469 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | GLS | Glutaminase. (669 aa) |
| | FSCN1 | Fascin. (493 aa) |
| | PIK3R2 | Uncharacterized protein. (624 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | LOC105585293 | Uncharacterized protein. (290 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa) |
| | BMF | Bcl2 modifying factor. (184 aa) |
| | ENSCATP00000025923 | Uncharacterized protein. (618 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | TNR | Tenascin R. (1358 aa) |
| | HNRNPK | Uncharacterized protein. (466 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | IRS2 | Insulin receptor substrate 2. (1338 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (237 aa) |
| | HMGA2 | High mobility group AT-hook 2. (147 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (861 aa) |
| | RPS6KA5 | Non-specific serine/threonine protein kinase. (896 aa) |
| | ZEB2 | Zinc finger E-box binding homeobox 2. (1253 aa) |
| | CD44 | CD44 molecule (Indian blood group). (742 aa) |
| | NOTCH4 | Notch receptor 4. (2000 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | MMP16 | Matrix metallopeptidase 16. (607 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3073 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | TRIM71 | Tripartite motif containing 71. (868 aa) |
| | E2F3 | E2F transcription factor 3. (467 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | ENSCATP00000034959 | C2H2-type domain-containing protein. (246 aa) |
| | ENSCATP00000035237 | ROKNT domain-containing protein. (71 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (950 aa) |
| | TPM3 | Uncharacterized protein; Belongs to the tropomyosin family. (285 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | TNC | Tenascin C. (2201 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1537 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | SIRT1 | Sirtuin 1. (744 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (974 aa) |
| | ENSCATP00000036747 | Uncharacterized protein. (391 aa) |
| | ENSCATP00000037667 | Protein kinase domain-containing protein. (365 aa) |
| | IGF2BP1 | Insulin like growth factor 2 mRNA binding protein 1. (583 aa) |
| | NOTCH2 | Notch receptor 2. (2610 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | ENSCATP00000038453 | Uncharacterized protein; Belongs to the peptidase C14A family. (262 aa) |
| | ENSCATP00000038535 | E2F_CC-MB domain-containing protein. (193 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (597 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | RASSF1 | Ras association domain family member 1. (340 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) |
| | ENSCATP00000040503 | FERM domain-containing protein. (476 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2301 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1404 aa) |
| | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa) |
| | NOTCH3 | Notch receptor 3. (2321 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | PLAU | Plasminogen activator, urokinase. (428 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (356 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | FOXP1 | Forkhead box P1. (693 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (474 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (233 aa) |
| | CDCA5 | Cell division cycle associated 5. (307 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | HMOX1 | Heme oxygenase 1. (311 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
