STRINGSTRING
RAP1A RAP1A ENSCATP00000001579 ENSCATP00000001579 PAK5 PAK5 SOS1 SOS1 LOC105571986 LOC105571986 ENSCATP00000004469 ENSCATP00000004469 ERAS ERAS CDKN1A CDKN1A PAK6 PAK6 ENSCATP00000005869 ENSCATP00000005869 GAB1 GAB1 LOC105584562 LOC105584562 AKT1 AKT1 HIF1A HIF1A TGFB3 TGFB3 RAPGEF1 RAPGEF1 TGFB1 TGFB1 ENSCATP00000010452 ENSCATP00000010452 TFE3 TFE3 MAPK3 MAPK3 KRAS KRAS VEGFA VEGFA TGFB2 TGFB2 RAC1 RAC1 PRCC PRCC ARAF ARAF ENSCATP00000012999 ENSCATP00000012999 ENSCATP00000013162 ENSCATP00000013162 MAP2K2 MAP2K2 HRAS HRAS CUL2 CUL2 MAPK1 MAPK1 PAK1 PAK1 SLC2A1 SLC2A1 ENSCATP00000017084 ENSCATP00000017084 ELOB ELOB BAD BAD LOC105572981 LOC105572981 AKT3 AKT3 PTPN11 PTPN11 BRAF BRAF ARNT2 ARNT2 CDC42 CDC42 ELOC ELOC PIK3R2 PIK3R2 ETS1 ETS1 PIK3CB PIK3CB RAF1 RAF1 RBX1 RBX1 ENSCATP00000026377 ENSCATP00000026377 PIK3CA PIK3CA VHL VHL CSDE1 CSDE1 PIK3R3 PIK3R3 PAK3 PAK3 PIK3R1 PIK3R1 EGLN2 EGLN2 MAP2K1 MAP2K1 PPP1R14B PPP1R14B ENSCATP00000030673 ENSCATP00000030673 AKT2 AKT2 PAK2 PAK2 CREBBP CREBBP ENSCATP00000033319 ENSCATP00000033319 FLCN FLCN CRKL CRKL HGF HGF EGLN3 EGLN3 NRAS NRAS EPAS1 EPAS1 ENSCATP00000037667 ENSCATP00000037667 ARNT ARNT PIK3CD PIK3CD CRK CRK PAK4 PAK4 EGLN1 EGLN1 SOS2 SOS2 PDGFB PDGFB TGFA TGFA MET MET EP300 EP300 GRB2 GRB2 ENSCATP00000000152 ENSCATP00000000152 ENSCATP00000042801 ENSCATP00000042801 RAP1B RAP1B ENSCATP00000044421 ENSCATP00000044421 FH FH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ENSCATP00000001579Uncharacterized protein. (97 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
LOC105571986Uncharacterized protein. (189 aa)
ENSCATP00000004469Uncharacterized protein. (191 aa)
ERASES cell expressed Ras. (233 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
ENSCATP00000005869Uncharacterized protein. (526 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
LOC105584562Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (831 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1303 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENSCATP00000010452Uncharacterized protein. (596 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
RAC1Uncharacterized protein. (212 aa)
PRCCProline rich mitotic checkpoint control factor. (491 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
ENSCATP00000012999Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
ENSCATP00000013162Uncharacterized protein. (173 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CUL2Cullin 2; Belongs to the cullin family. (764 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (504 aa)
ENSCATP00000017084Uncharacterized protein. (185 aa)
ELOBElongin B. (167 aa)
BADBCL2 associated agonist of cell death. (167 aa)
LOC105572981Uncharacterized protein. (132 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (552 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (762 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (723 aa)
CDC42Uncharacterized protein. (191 aa)
ELOCElongin C. (112 aa)
PIK3R2Uncharacterized protein. (624 aa)
ETS1ETS proto-oncogene 1, transcription factor. (548 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
RAF1Uncharacterized protein. (668 aa)
RBX1Ring-box 1. (108 aa)
ENSCATP00000026377Uncharacterized protein. (170 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
VHLVon Hippel-Lindau tumor suppressor. (213 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (405 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (344 aa)
PPP1R14BUncharacterized protein. (207 aa)
ENSCATP00000030673Uncharacterized protein. (652 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CREBBPCREB binding protein. (2442 aa)
ENSCATP00000033319Uncharacterized protein. (66 aa)
FLCNFolliculin. (680 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
ENSCATP00000037667Protein kinase domain-containing protein. (365 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PAK4Non-specific serine/threonine protein kinase. (597 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (426 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
TGFATransforming growth factor alpha. (166 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
EP300E1A binding protein p300. (2411 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSCATP00000000152Uncharacterized protein. (64 aa)
ENSCATP00000042801Uncharacterized protein. (136 aa)
RAP1BUncharacterized protein. (184 aa)
ENSCATP00000044421Uncharacterized protein. (441 aa)
FHFumarate hydratase. (510 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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