STRINGSTRING
BRMS1 BRMS1 FCSK FCSK ENSMFAP00000000260 ENSMFAP00000000260 RAB35 RAB35 ENSMFAP00000000762 ENSMFAP00000000762 SPDYA SPDYA HUWE1 HUWE1 PRDM16 PRDM16 LOC102119988 LOC102119988 MRC1 MRC1 HNRNPK HNRNPK ENSMFAP00000001953 ENSMFAP00000001953 GPNMB GPNMB DPP9 DPP9 SMYD3 SMYD3 MMP14 MMP14 ATP6V1G1 ATP6V1G1 GPR143 GPR143 HMGCL HMGCL DMRTA1 DMRTA1 ENSMFAP00000004047 ENSMFAP00000004047 GNA13 GNA13 YWHAZ YWHAZ PNPT1 PNPT1 PDIA3 PDIA3 AMBRA1 AMBRA1 FLOT1 FLOT1 ADAMTS14 ADAMTS14 SPRTN SPRTN RAB7A RAB7A YTHDF1 YTHDF1 DCD DCD TSC22D3 TSC22D3 VPS18 VPS18 ENSMFAP00000008676 ENSMFAP00000008676 BRAF BRAF TAPBP TAPBP RNF157 RNF157 PPIB PPIB CCR10 CCR10 IL24 IL24 VRK1 VRK1 NDC1 NDC1 HSPB8 HSPB8 GLTP GLTP NME1-NME2 NME1-NME2 CCNL2 CCNL2 PHLPP1 PHLPP1 CTSB CTSB FZD5 FZD5 ACTBL2 ACTBL2 ABCB5 ABCB5 ENSMFAP00000012326 ENSMFAP00000012326 ENSMFAP00000012353 ENSMFAP00000012353 ANXA2R ANXA2R UBE2O UBE2O UBE2C UBE2C CD8A CD8A MIA MIA SCIN SCIN LOC102145093 LOC102145093 ENSMFAP00000013482 ENSMFAP00000013482 PRDX1 PRDX1 ENSMFAP00000013903 ENSMFAP00000013903 ENSMFAP00000013911 ENSMFAP00000013911 LOC102127640 LOC102127640 RAB5B RAB5B ENSMFAP00000014199 ENSMFAP00000014199 ENSMFAP00000014202 ENSMFAP00000014202 LOC102128144 LOC102128144 CCDC85B CCDC85B ANXA2 ANXA2 CPEB1 CPEB1 PARP9 PARP9 TRPV2 TRPV2 BATF BATF EPHA3 EPHA3 MAGEC3 MAGEC3 CSPG4 CSPG4 KCTD16 KCTD16 ENSMFAP00000017173 ENSMFAP00000017173 AHCY AHCY TRUB1 TRUB1 ENSMFAP00000017556 ENSMFAP00000017556 SLC3A2 SLC3A2 CANX CANX SLC2A1 SLC2A1 ENSMFAP00000017801 ENSMFAP00000017801 SHPK SHPK MVP MVP SLC3A2-2 SLC3A2-2 ENSMFAP00000018412 ENSMFAP00000018412 LOC102119362 LOC102119362 ENSMFAP00000018765 ENSMFAP00000018765 DEPDC1B DEPDC1B FANCD2 FANCD2 TRIM9 TRIM9 IPO13 IPO13 SLC24A5 SLC24A5 MAP3K3 MAP3K3 EIF2AK4 EIF2AK4 MAT2B MAT2B ENSMFAP00000021941 ENSMFAP00000021941 SLC16A1 SLC16A1 BLM BLM ENSMFAP00000022812 ENSMFAP00000022812 YWHAB YWHAB HIF1AN HIF1AN GAK GAK WASL WASL FAP FAP ENSMFAP00000024148 ENSMFAP00000024148 LOX LOX PDCD6IP PDCD6IP EPS15 EPS15 ENSMFAP00000025331 ENSMFAP00000025331 SLAMF9 SLAMF9 SERPINF1 SERPINF1 PLA1A PLA1A ENSMFAP00000026164 ENSMFAP00000026164 CTHRC1 CTHRC1 DCT DCT KCTD8 KCTD8 RAB38 RAB38 SLC1A5 SLC1A5 CDCA2 CDCA2 CSGALNACT1 CSGALNACT1 ATP6V1C1 ATP6V1C1 PLA2G2C PLA2G2C BIRC7 BIRC7 TYR TYR ARG1 ARG1 GANAB GANAB MLANA MLANA PLAT PLAT ENSMFAP00000029982 ENSMFAP00000029982 LAMTOR5 LAMTOR5 PAPOLG PAPOLG ENSMFAP00000030878 ENSMFAP00000030878 ST8SIA1 ST8SIA1 ESCO1 ESCO1 PSCA PSCA NRAS NRAS ITGA5 ITGA5 LGALS1 LGALS1 HSP90B1 HSP90B1 MC1R MC1R MMP2 MMP2 VEZF1 VEZF1 ENSMFAP00000032552 ENSMFAP00000032552 ANXA6 ANXA6 HSP90AA1 HSP90AA1 EZR EZR IL4 IL4 ENPP2 ENPP2 USP10 USP10 RAB27A RAB27A RAN RAN FBXO42 FBXO42 IFIH1 IFIH1 ENSMFAP00000034738 ENSMFAP00000034738 SLC1A4 SLC1A4 SLC45A2 SLC45A2 ATRIP ATRIP STOM STOM MCAM MCAM FAM187B FAM187B ENSMFAP00000036562 ENSMFAP00000036562 ENSMFAP00000036680 ENSMFAP00000036680 ITGB1 ITGB1 RAB2A RAB2A UTP20 UTP20 SLC9A1 SLC9A1 MTMR12 MTMR12 ENSMFAP00000037561 ENSMFAP00000037561 SDCBP SDCBP SND1 SND1 MITF MITF MELTF MELTF FASN FASN HSP90AB1 HSP90AB1 HSPA8 HSPA8 P4HB P4HB ENSMFAP00000038879 ENSMFAP00000038879 CTBP2 CTBP2 UGCG UGCG TYRP1 TYRP1 ENSMFAP00000040007 ENSMFAP00000040007 SDC1 SDC1 NFE2L2 NFE2L2 FOXK1 FOXK1 ENSMFAP00000040719 ENSMFAP00000040719 ENSMFAP00000041402 ENSMFAP00000041402 NCOA4 NCOA4 ENSMFAP00000041691 ENSMFAP00000041691 RNF20 RNF20 YWHAE YWHAE ADAMTS1 ADAMTS1 HSPA5 HSPA5 CIP2A CIP2A ENSMFAP00000042475 ENSMFAP00000042475 BSG BSG BAZ2B BAZ2B ENSMFAP00000043889 ENSMFAP00000043889 CLTC CLTC GIT1 GIT1 HMOX1 HMOX1 LOC107127874 LOC107127874 PDIA6 PDIA6 FZD8 FZD8 ENSMFAP00000045057 ENSMFAP00000045057 ANXA5 ANXA5 ILF3 ILF3 GRK5 GRK5 PREX1 PREX1 TFRC TFRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRMS1Uncharacterized protein. (262 aa)
FCSKFucose kinase. (1084 aa)
ENSMFAP00000000260Uncharacterized protein. (454 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
ENSMFAP00000000762Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (313 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4390 aa)
PRDM16PR/SET domain 16. (1276 aa)
LOC102119988Uncharacterized protein. (173 aa)
MRC1Mannose receptor C-type 1. (1456 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...] (464 aa)
ENSMFAP00000001953UBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa)
GPNMBGlycoprotein nmb. (561 aa)
DPP9Dipeptidyl peptidase 9. (537 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
GPR143G protein-coupled receptor 143. (407 aa)
HMGCLHydroxymethylglutaryl-CoA lyase, mitochondrial; Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3- methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. (315 aa)
DMRTA1DMRT like family A1. (559 aa)
ENSMFAP00000004047S1 motif domain-containing protein. (248 aa)
GNA13G protein subunit alpha 13. (377 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (257 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (783 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ADAMTS14ADAM metallopeptidase with thrombospondin type 1 motif 14. (1223 aa)
SPRTNSprT-like N-terminal domain. (488 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (559 aa)
DCDDermcidin. (119 aa)
TSC22D3TSC22 domain family member 3. (302 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
ENSMFAP00000008676Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (301 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (762 aa)
TAPBPTAP binding protein. (504 aa)
RNF157Ring finger protein 157. (680 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa)
IL24Interleukin 24. (207 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
NDC1NDC1 transmembrane nucleoporin. (523 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
GLTPGlycolipid transfer protein. (209 aa)
NME1-NME2Nucleoside diphosphate kinase. (292 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (520 aa)
PHLPP1PH domain and leucine rich repeat protein phosphatase 1. (1253 aa)
CTSBCathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family. (339 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
ACTBL2Actin beta like 2. (376 aa)
ABCB5ATP binding cassette subfamily B member 5. (1257 aa)
ENSMFAP00000012326Uncharacterized protein. (103 aa)
ENSMFAP00000012353Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (435 aa)
ANXA2RAnnexin A2 receptor. (193 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
UBE2CUbiquitin-conjugating enzyme E2 C; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CD8ACD8a molecule. (235 aa)
MIAMIA-RAB4B readthrough (NMD candidate). (131 aa)
SCINScinderin. (715 aa)
LOC102145093Ubiquitin-conjugating enzyme E2 C. (179 aa)
ENSMFAP00000013482Olfactory receptor. (316 aa)
PRDX1Thioredoxin domain-containing protein. (199 aa)
ENSMFAP00000013903AdoHcyase_NAD domain-containing protein; Belongs to the adenosylhomocysteinase family. (432 aa)
ENSMFAP00000013911Galectin. (134 aa)
LOC102127640Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (437 aa)
RAB5BUncharacterized protein. (221 aa)
ENSMFAP00000014199HATPase_c domain-containing protein. (307 aa)
ENSMFAP00000014202Uncharacterized protein; Belongs to the heat shock protein 70 family. (571 aa)
LOC102128144UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CCDC85BCoiled-coil domain containing 85B. (202 aa)
ANXA2Annexin. (357 aa)
CPEB1Cytoplasmic polyadenylation element binding protein 1. (613 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
EPHA3EPH receptor A3. (984 aa)
MAGEC3MAGE family member C3. (576 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2279 aa)
KCTD16Potassium channel tetramerization domain containing 16. (428 aa)
ENSMFAP00000017173PDZ domain-containing protein. (255 aa)
AHCYAdenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. (455 aa)
TRUB1TruB pseudouridine synthase family member 1. (350 aa)
ENSMFAP00000017556Uncharacterized protein. (292 aa)
SLC3A2Uncharacterized protein. (148 aa)
CANXCalnexin. (592 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
ENSMFAP00000017801Uncharacterized protein. (170 aa)
SHPKFGGY_N domain-containing protein. (479 aa)
MVPMajor vault protein. (893 aa)
SLC3A2-2Aamy domain-containing protein. (483 aa)
ENSMFAP00000018412HATPase_c domain-containing protein. (644 aa)
LOC102119362Uncharacterized protein. (202 aa)
ENSMFAP00000018765GLTP domain-containing protein. (190 aa)
DEPDC1BDEP domain-containing protein 1B. (535 aa)
FANCD2Uncharacterized protein. (1415 aa)
TRIM9Tripartite motif containing 9. (795 aa)
IPO13Importin 13. (963 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1248 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (334 aa)
ENSMFAP00000021941Uncharacterized protein. (362 aa)
SLC16A1MFS domain-containing protein. (500 aa)
BLMBLM RecQ like helicase. (1416 aa)
ENSMFAP00000022812Uncharacterized protein. (421 aa)
YWHAB14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] (246 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (349 aa)
GAKCyclin G associated kinase. (1311 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
ENSMFAP00000024148Uncharacterized protein. (155 aa)
LOXLysyl oxidase. (417 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (898 aa)
ENSMFAP00000025331Uncharacterized protein. (259 aa)
SLAMF9Ig-like domain-containing protein. (284 aa)
SERPINF1SERPIN domain-containing protein; Belongs to the serpin family. (406 aa)
PLA1APhospholipase A1 member A. (456 aa)
ENSMFAP00000026164Uncharacterized protein. (282 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
DCTDopachrome tautomerase. (557 aa)
KCTD8Potassium channel tetramerization domain containing 8. (473 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
SLC1A5Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. (483 aa)
CDCA2Cell division cycle associated 2. (1019 aa)
CSGALNACT1Hexosyltransferase. (532 aa)
ATP6V1C1V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (382 aa)
PLA2G2CPhospholipase A(2). (151 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
TYRTyrosinase. (530 aa)
ARG1Arginase. (322 aa)
GANABNeutral alpha-glucosidase AB; Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia. (969 aa)
MLANAMelan-A. (118 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
ENSMFAP00000029982Uncharacterized protein. (102 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (169 aa)
PAPOLGPoly(A) polymerase gamma. (736 aa)
ENSMFAP00000030878Uncharacterized protein. (74 aa)
ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (356 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (840 aa)
PSCAToxin_TOLIP domain-containing protein. (102 aa)
NRASUncharacterized protein. (189 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
LGALS1Galectin. (135 aa)
HSP90B1Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. (804 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (342 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
VEZF1Vascular endothelial zinc finger 1. (511 aa)
ENSMFAP00000032552ROKNT domain-containing protein. (71 aa)
ANXA6Annexin. (680 aa)
HSP90AA1Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (831 aa)
EZREzrin. (586 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
USP10Ubiquitin specific peptidase 10; Belongs to the peptidase C19 family. (810 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
RANGTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] (233 aa)
FBXO42F-box protein 42. (716 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
ENSMFAP00000034738KH domain-containing protein. (380 aa)
SLC1A4Amino acid transporter. (538 aa)
SLC45A2Solute carrier family 45 member 2. (530 aa)
ATRIPATR-interacting protein; Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein (By similarity). (791 aa)
STOMStomatin. (288 aa)
MCAMMelanoma cell adhesion molecule. (649 aa)
FAM187BProtein FAM187B. (369 aa)
ENSMFAP00000036562Uncharacterized protein. (92 aa)
ENSMFAP00000036680RWD domain-containing protein. (136 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
RAB2ARas-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex. (212 aa)
UTP20UTP20 small subunit processome component. (2785 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
MTMR12Myotubularin related protein 12. (747 aa)
ENSMFAP00000037561Uncharacterized protein. (115 aa)
SDCBPUncharacterized protein. (324 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
MITFMelanocyte inducing transcription factor. (519 aa)
MELTFMelanotransferrin. (812 aa)
FASNFatty acid synthase. (2502 aa)
HSP90AB1Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (724 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
P4HBProtein disulfide-isomerase. (510 aa)
ENSMFAP00000038879GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (206 aa)
CTBP2C-terminal binding protein 2. (985 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
TYRP1Tyrosinase related protein 1. (537 aa)
ENSMFAP00000040007UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
FOXK1Forkhead box K1. (638 aa)
ENSMFAP0000004071914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
ENSMFAP00000041402Uncharacterized protein. (155 aa)
NCOA4Nuclear receptor coactivator 4. (651 aa)
ENSMFAP0000004169114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
RNF20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa)
YWHAE14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (906 aa)
ENSMFAP00000042475Uncharacterized protein. (290 aa)
BSGBasigin (Ok blood group). (366 aa)
BAZ2BBromodomain adjacent to zinc finger domain 2B. (2169 aa)
ENSMFAP00000043889Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
GIT1GIT ArfGAP 1. (776 aa)
HMOX1Uncharacterized protein. (288 aa)
LOC107127874UN_NPL4 domain-containing protein. (130 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (492 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa)
ENSMFAP00000045057Uncharacterized protein. (295 aa)
ANXA5Annexin A5; This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. (320 aa)
ILF3Interleukin enhancer binding factor 3. (899 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1661 aa)
TFRCTransferrin receptor. (760 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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