STRINGSTRING
HNRNPD HNRNPD NUDT21 NUDT21 YBX1 YBX1 ENSMFAP00000000762 ENSMFAP00000000762 BCAR1 BCAR1 ENSMFAP00000001072 ENSMFAP00000001072 SNW1 SNW1 ENSMFAP00000001201 ENSMFAP00000001201 HNRNPU HNRNPU TNS1 TNS1 LPAR2 LPAR2 LOC102133652 LOC102133652 MAP1A MAP1A HNRNPDL HNRNPDL TOP2A TOP2A PARP1 PARP1 HNRNPA2B1 HNRNPA2B1 ENSMFAP00000007094 ENSMFAP00000007094 ALYREF ALYREF KHDRBS1 KHDRBS1 TGIF2 TGIF2 FSCN1 FSCN1 DAZAP1 DAZAP1 SFPQ SFPQ GPR68 GPR68 ENSMFAP00000009958 ENSMFAP00000009958 H1-5 H1-5 ENSMFAP00000011451 ENSMFAP00000011451 SLC34A2 SLC34A2 YTHDF2 YTHDF2 ENSMFAP00000014202 ENSMFAP00000014202 ACTL6A ACTL6A FOLR1 FOLR1 ENSMFAP00000014996 ENSMFAP00000014996 ENSMFAP00000015784 ENSMFAP00000015784 ENSMFAP00000016862 ENSMFAP00000016862 AKT1 AKT1 PLEC PLEC MN1 MN1 PHGDH PHGDH KLK7 KLK7 EIF5A2 EIF5A2 KRT7 KRT7 RALY RALY ENSMFAP00000021941 ENSMFAP00000021941 LMNB1 LMNB1 ENSMFAP00000022812 ENSMFAP00000022812 EML4 EML4 NMT1 NMT1 DEK DEK ENTPD2 ENTPD2 ENSMFAP00000024414 ENSMFAP00000024414 POLDIP3 POLDIP3 G3BP2 G3BP2 DIAPH2 DIAPH2 ENSMFAP00000026895 ENSMFAP00000026895 PABPC1 PABPC1 LMNA LMNA ALDH1A3 ALDH1A3 TGM2 TGM2 CDC73 CDC73 ENSMFAP00000030668 ENSMFAP00000030668 ULBP4 ULBP4 ESS2 ESS2 DIAPH1 DIAPH1 PIWIL1 PIWIL1 TOP1 TOP1 ARMC8 ARMC8 G3BP1 G3BP1 ENSMFAP00000032199 ENSMFAP00000032199 ENSMFAP00000032386 ENSMFAP00000032386 CALCR CALCR ENOX2 ENOX2 ENSMFAP00000033787 ENSMFAP00000033787 PIWIL3 PIWIL3 TMPRSS3 TMPRSS3 RBM3 RBM3 ENSMFAP00000034697 ENSMFAP00000034697 ENSMFAP00000035469 ENSMFAP00000035469 DFFA DFFA ENSMFAP00000035925 ENSMFAP00000035925 SMAD1 SMAD1 API5 API5 ABCC5 ABCC5 HSPA8 HSPA8 EWSR1 EWSR1 TRIM28 TRIM28 SNAP23 SNAP23 ATG4B ATG4B PRPF8 PRPF8 MSX2 MSX2 STIM2 STIM2 WTAP WTAP BCL2L11 BCL2L11 ENSMFAP00000043809 ENSMFAP00000043809 ENSMFAP00000044068 ENSMFAP00000044068 SMAD5 SMAD5 FKBP4 FKBP4 ENSMFAP00000045669 ENSMFAP00000045669
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
YBX1Y-box binding protein 1. (324 aa)
ENSMFAP00000000762Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
ENSMFAP00000001072Uncharacterized protein. (113 aa)
SNW1SNW domain containing 1. (571 aa)
ENSMFAP00000001201Uncharacterized protein. (378 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
TNS1Tensin 1. (1740 aa)
LPAR2Lysophosphatidic acid receptor 2; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation (By similarity). (351 aa)
LOC102133652MHC_I-like_Ag-recog domain-containing protein. (263 aa)
MAP1AMicrotubule associated protein 1A. (3042 aa)
HNRNPDLHeterogeneous nuclear ribonucleoprotein D like. (420 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
HNRNPA2B1Uncharacterized protein. (353 aa)
ENSMFAP00000007094Uncharacterized protein. (381 aa)
ALYREFAly/REF export factor. (257 aa)
KHDRBS1KH domain-containing protein. (443 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
FSCN1Fascin. (493 aa)
DAZAP1DAZ associated protein 1. (408 aa)
SFPQSplicing factor proline and glutamine rich. (707 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ENSMFAP00000009958Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (574 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
ENSMFAP00000011451Uncharacterized protein. (144 aa)
SLC34A2Solute carrier family 34 member 2. (689 aa)
YTHDF2YTH domain-containing family protein 2; Specifically recognizes and binds N6-methyladenosine (m6A)- containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in mRNA degradation. Required maternally to regulate oocyte maturation: probably acts by binding to m6A-containing mRNAs, thereby regulating maternal transcript dosage during oocyte maturation, which is essential for the competence o [...] (593 aa)
ENSMFAP00000014202Uncharacterized protein; Belongs to the heat shock protein 70 family. (571 aa)
ACTL6AActin-like protein 6A; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Belongs to the neural progenitors-specific chromatin remo [...] (429 aa)
FOLR1Folate receptor alpha. (257 aa)
ENSMFAP00000014996Uncharacterized protein. (308 aa)
ENSMFAP00000015784SAP domain-containing protein. (344 aa)
ENSMFAP00000016862Uncharacterized protein. (372 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PLECPlectin. (4684 aa)
MN1MN1 proto-oncogene, transcriptional regulator. (1320 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (551 aa)
KLK7Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (186 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
KRT7Keratin 7; Belongs to the intermediate filament family. (469 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (309 aa)
ENSMFAP00000021941Uncharacterized protein. (362 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
ENSMFAP00000022812Uncharacterized protein. (421 aa)
EML4EMAP like 4. (1006 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
DEKSAP domain-containing protein. (375 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
ENSMFAP00000024414Uncharacterized protein. (275 aa)
POLDIP3DNA polymerase delta interacting protein 3. (425 aa)
G3BP2G3BP stress granule assembly factor 2. (482 aa)
DIAPH2Diaphanous related formin 2. (1099 aa)
ENSMFAP00000026895RRM domain-containing protein. (350 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (663 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
TGM2Transglutaminase 2. (687 aa)
CDC73Cell division cycle 73. (531 aa)
ENSMFAP00000030668Uncharacterized protein. (305 aa)
ULBP4MHC_I-like_Ag-recog domain-containing protein. (247 aa)
ESS2Ess-2 splicing factor homolog. (476 aa)
DIAPH1Diaphanous related formin 1. (1222 aa)
PIWIL1Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (861 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
ARMC8Uncharacterized protein. (673 aa)
G3BP1G3BP stress granule assembly factor 1. (466 aa)
ENSMFAP00000032199Uncharacterized protein. (314 aa)
ENSMFAP00000032386Eukaryotic translation initiation factor 5A. (148 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (517 aa)
ENOX2Ecto-NOX disulfide-thiol exchanger 2. (581 aa)
ENSMFAP00000033787Uncharacterized protein. (251 aa)
PIWIL3Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family. (841 aa)
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (454 aa)
RBM3RRM domain-containing protein. (157 aa)
ENSMFAP00000034697RRM domain-containing protein. (135 aa)
ENSMFAP00000035469SAP domain-containing protein. (356 aa)
DFFADNA fragmentation factor subunit alpha. (331 aa)
ENSMFAP00000035925Uncharacterized protein. (535 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
API5Apoptosis inhibitor 5. (524 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
EWSR1Uncharacterized protein. (661 aa)
TRIM28Tripartite motif containing 28. (721 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
MSX2Msh homeobox 2. (267 aa)
STIM2Stromal interaction molecule 2. (840 aa)
WTAPUncharacterized protein. (396 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
ENSMFAP00000043809Uncharacterized protein. (125 aa)
ENSMFAP00000044068SAP domain-containing protein. (339 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
FKBP4Peptidylprolyl isomerase. (459 aa)
ENSMFAP00000045669SKIP_SNW domain-containing protein. (467 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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