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LRRC47 LRRC47 YARS1 YARS1 IAH1 IAH1 TARS3 TARS3 AARS1 AARS1 FDXACB1 FDXACB1 HARS1 HARS1 AARS2 AARS2 EARS2 EARS2 WARS2 WARS2 VARS1 VARS1 CARS1 CARS1 DARS1 DARS1 MARS1 MARS1 MARS2 MARS2 ENSMFAP00000011863 ENSMFAP00000011863 ENSMFAP00000012610 ENSMFAP00000012610 RARS1 RARS1 TARS2 TARS2 FARSA FARSA WARS1 WARS1 NARS1 NARS1 QRSL1 QRSL1 NARS2 NARS2 QARS1 QARS1 SARS2 SARS2 IARS1 IARS1 SARS1 SARS1 FARS2 FARS2 TARS1 TARS1 QRSL1-2 QRSL1-2 AIMP1 AIMP1 AIMP2 AIMP2 GATB GATB EPRS1 EPRS1 VARS2 VARS2 DARS2 DARS2 HARS2 HARS2 LARS2 LARS2 GATC GATC FAAH2 FAAH2 NFKBIL1 NFKBIL1 FARSB FARSB LARS1 LARS1 GARS1 GARS1 ENSMFAP00000041212 ENSMFAP00000041212 KARS1 KARS1 TMEM179B TMEM179B ASNSD1 ASNSD1 RARS2 RARS2 IARS2 IARS2 TMEM109 TMEM109 EEF1E1 EEF1E1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC47Leucine rich repeat containing 47. (527 aa)
YARS1Tyrosine--tRNA ligase. (503 aa)
IAH1Isoamyl acetate hydrolyzing esterase 1 (putative). (248 aa)
TARS3Threonyl-tRNA synthetase like 2. (801 aa)
AARS1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
FDXACB1Ferredoxin-fold anticodon binding domain containing 1. (624 aa)
HARS1Histidyl-tRNA synthetase. (509 aa)
AARS2Alanyl-tRNA synthetase 2, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (985 aa)
EARS2Probable glutamate--tRNA ligase, mitochondrial; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (523 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (369 aa)
VARS1Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa)
CARS1Cysteine--tRNA ligase, cytoplasmic. (831 aa)
DARS1Aspartyl-tRNA synthetase. (501 aa)
MARS1Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (908 aa)
MARS2Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (593 aa)
ENSMFAP00000011863Uncharacterized protein. (126 aa)
ENSMFAP00000012610Uncharacterized protein. (145 aa)
RARS1Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (660 aa)
TARS2Threonyl-tRNA synthetase 2, mitochondrial. (718 aa)
FARSAPhenylalanyl-tRNA synthetase subunit alpha. (550 aa)
WARS1WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa)
NARS1Asparagine--tRNA ligase, cytoplasmic; Catalyzes the attachment of asparagine to tRNA(Asn) in a two- step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induces immune response in a CCR3-dependent manner. (558 aa)
QRSL1Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (528 aa)
NARS2Asparaginyl-tRNA synthetase 2, mitochondrial. (477 aa)
QARS1Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
SARS2AA_TRNA_LIGASE_II domain-containing protein. (520 aa)
IARS1Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1420 aa)
SARS1Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16 [...] (491 aa)
FARS2Phenylalanyl-tRNA synthetase 2, mitochondrial. (451 aa)
TARS1Threonyl-tRNA synthetase. (740 aa)
QRSL1-2Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (484 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (321 aa)
AIMP2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (251 aa)
GATBUncharacterized protein. (429 aa)
EPRS1Glutamyl-prolyl-tRNA synthetase. (1512 aa)
VARS2Valyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1063 aa)
DARS2Aspartyl-tRNA synthetase 2, mitochondrial. (645 aa)
HARS2Histidyl-tRNA synthetase 2, mitochondrial. (506 aa)
LARS2Leucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (903 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (136 aa)
FAAH2Fatty acid amide hydrolase 2. (532 aa)
NFKBIL1NFKB inhibitor like 1. (381 aa)
FARSBB5 domain-containing protein. (589 aa)
LARS1Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa)
GARS1Glycyl-tRNA synthetase. (738 aa)
ENSMFAP00000041212Uncharacterized protein; Belongs to the glutamine synthetase family. (196 aa)
KARS1Lysine--tRNA ligase. (625 aa)
TMEM179BTransmembrane protein 179B. (219 aa)
ASNSD1Asparagine synthetase domain-containing protein 1. (643 aa)
RARS2Arginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (582 aa)
IARS2Isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1012 aa)
TMEM109Transmembrane protein 109. (243 aa)
EEF1E1GST C-terminal domain-containing protein. (174 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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