STRINGSTRING
RAB1B RAB1B RAB6A RAB6A RAB18 RAB18 TBC1D20 TBC1D20 RAB3GAP1 RAB3GAP1 GDI2 GDI2 RAB6B RAB6B RIC1 RIC1 RAB3GAP2 RAB3GAP2 RGP1 RGP1 GDI1 GDI1 RAB1A RAB1A ENSMFAP00000044945 ENSMFAP00000044945 RAB41 RAB41
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB1BRas-related protein Rab-1B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (By similarity). Regulates [...] (214 aa)
RAB6ARAB6A, member RAS oncogene family. (208 aa)
RAB18Uncharacterized protein. (235 aa)
TBC1D20TBC1 domain family member 20. (407 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
GDI2Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (445 aa)
RAB6BRAB6B, member RAS oncogene family. (208 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1422 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1393 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
GDI1Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity). (477 aa)
RAB1AUncharacterized protein. (217 aa)
ENSMFAP00000044945Uncharacterized protein. (199 aa)
RAB41RAB41, member RAS oncogene family. (224 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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