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EPN3 EPN3 CLTB CLTB NECAP2 NECAP2 AP4B1 AP4B1 AP2M1 AP2M1 AP2S1 AP2S1 AP2A2 AP2A2 NECAP1 NECAP1 CLTCL1 CLTCL1 AP2B1 AP2B1 GAK GAK ITSN1 ITSN1 EPS15 EPS15 DNAJC6 DNAJC6 CLTA CLTA SGIP1 SGIP1 SNAP91 SNAP91 FCHO1 FCHO1 ITSN2 ITSN2 AP2A1 AP2A1 GAS7 GAS7 PICALM PICALM EPN2 EPN2 HIP1R HIP1R CLTC CLTC CLHC1 CLHC1 EPS15L1 EPS15L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPN3Epsin 3. (632 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
NECAP2NECAP endocytosis associated 2. (273 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
NECAP1DUF1681 domain-containing protein. (275 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1640 aa)
AP2B1AP complex subunit beta. (951 aa)
GAKCyclin G associated kinase. (1311 aa)
ITSN1Intersectin 1. (1625 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (898 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (970 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)
SNAP91Synaptosome associated protein 91. (907 aa)
FCHO1FCH domain only 1. (870 aa)
ITSN2Intersectin 2. (1697 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
GAS7Growth arrest specific 7. (476 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
EPN2Epsin 2. (641 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (910 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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