STRINGSTRING
F5 F5 PLG PLG SERPINA10 SERPINA10 F13B F13B FGG FGG HP HP F13A1 F13A1 SERPINA2 SERPINA2 TFPI TFPI LPA LPA SERPIND1 SERPIND1 SERPINC1 SERPINC1 F2 F2 FABP1 FABP1 GC GC F12 F12 HRG HRG APOH APOH F7 F7 SERPINB2 SERPINB2 TFPI2 TFPI2 SERPINA1 SERPINA1 PROS1 PROS1 F10 F10 SERPINE2 SERPINE2 PLAUR PLAUR ENSMFAP00000025660 ENSMFAP00000025660 CELA1 CELA1 PROC PROC F9 F9 FGB FGB FGA FGA KLKB1 KLKB1 F11 F11 F3 F3 AFM AFM PLAT PLAT PROZ PROZ AHSG AHSG A2M A2M SERPINA5 SERPINA5 ITIH4 ITIH4 PLAU PLAU SERPINF2 SERPINF2 ORM1 ORM1 ITIH2 ITIH2 AMBP AMBP HPX HPX F8 F8 SERPINE1 SERPINE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2181 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (811 aa)
SERPINA10Serpin family A member 10; Belongs to the serpin family. (471 aa)
F13BCoagulation factor XIII B chain. (661 aa)
FGGFibrinogen gamma chain. (453 aa)
HPPeptidase S1 domain-containing protein. (426 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
SERPINA2Serpin family A member 2 (gene/pseudogene); Belongs to the serpin family. (419 aa)
TFPITissue factor pathway inhibitor. (304 aa)
LPAUncharacterized protein. (400 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (464 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (620 aa)
FABP1Fatty acid binding protein 1. (127 aa)
GCGC vitamin D binding protein. (490 aa)
F12Coagulation factor XII. (615 aa)
HRGHistidine rich glycoprotein. (525 aa)
APOHUncharacterized protein. (355 aa)
F7Coagulation factor VII. (472 aa)
SERPINB2Serpin family B member 2; Belongs to the serpin family. (415 aa)
TFPI2Tissue factor pathway inhibitor. (235 aa)
SERPINA1Serpin family A member 1; Belongs to the serpin family. (418 aa)
PROS1Protein S. (676 aa)
F10Coagulation factor X. (488 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
PLAURUrokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). (335 aa)
ENSMFAP00000025660Uncharacterized protein. (342 aa)
CELA1Chymotrypsin-like elastase family member 1; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. (261 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (462 aa)
F9Coagulation factor IX. (461 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (928 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (638 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
F3Coagulation factor III, tissue factor. (296 aa)
AFMAfamin. (600 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)
AHSGAlpha 2-HS glycoprotein. (367 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
SERPINA5Serpin family A member 5; Belongs to the serpin family. (477 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (935 aa)
PLAUPlasminogen activator, urokinase. (430 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
ORM1Orosomucoid 1. (180 aa)
ITIH2Inter-alpha-trypsin inhibitor heavy chain 2. (946 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (352 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2351 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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