STRINGSTRING
BRS3 BRS3 CCK CCK GRPR GRPR LEPR LEPR UTS2R UTS2R MC4R MC4R NTS NTS MLNR MLNR NTSR1 NTSR1 TRHR TRHR NLN NLN MLN MLN GAST GAST NMB NMB NMS NMS AGRP AGRP NTSR2 NTSR2 NMUR2 NMUR2 GHRL GHRL LEP LEP NPS NPS MCHR1 MCHR1 TRH TRH ENSMFAP00000031138 ENSMFAP00000031138 MC1R MC1R UTS2B UTS2B PMCH PMCH CCKAR CCKAR NMBR NMBR GRP GRP CCKBR CCKBR NMU NMU NMUR1 NMUR1 GHSR GHSR UTS2 UTS2 MBOAT4 MBOAT4 MCHR2 MCHR2 QRFPR QRFPR NPSR1 NPSR1 POMC POMC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRS3Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (398 aa)
CCKCholecystokinin-58 desnonopeptide; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Belongs to the gastrin/cholecystokinin family. (115 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
LEPRLeptin receptor. (1163 aa)
UTS2RUrotensin 2 receptor; Belongs to the G-protein coupled receptor 1 family. (389 aa)
MC4RMelanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). (332 aa)
NTSNeurotensin. (170 aa)
MLNRMotilin receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
TRHRThyrotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (398 aa)
NLNNeurolysin. (704 aa)
MLNMotilin. (114 aa)
GASTGastrin. (104 aa)
NMBNeuromedin B. (153 aa)
NMSNeuromedin S. (153 aa)
AGRPAgouti related neuropeptide. (132 aa)
NTSR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (408 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
NPSNeuropeptide S. (89 aa)
MCHR1Melanin concentrating hormone receptor 1. (422 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (234 aa)
ENSMFAP00000031138Uncharacterized protein. (68 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (342 aa)
UTS2BUrotensin 2B. (118 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
GRPGastrin releasing peptide. (100 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (513 aa)
NMUNeuromedin U. (115 aa)
NMUR1Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (426 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
UTS2Urotensin 2. (140 aa)
MBOAT4Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (435 aa)
MCHR2Melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. (340 aa)
QRFPRPyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
POMCProopiomelanocortin. (265 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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