STRINGSTRING
EFTUD2 EFTUD2 SNRNP25 SNRNP25 ENSMFAP00000030958 ENSMFAP00000030958 ENSMFAP00000030936 ENSMFAP00000030936 TRA2B TRA2B SMU1 SMU1 ESS2 ESS2 ENSMFAP00000030668 ENSMFAP00000030668 SF3B4 SF3B4 SNRPN SNRPN SNRPD1 SNRPD1 C9orf78 C9orf78 SYF2 SYF2 SRSF4 SRSF4 SNRPA SNRPA C11orf58 C11orf58 PSIP1 PSIP1 METTL14 METTL14 SRPK2 SRPK2 PRR3 PRR3 SRSF2 SRSF2 SF3B3 SF3B3 RBM8A RBM8A ENSMFAP00000026895 ENSMFAP00000026895 DHX8 DHX8 SNIP1 SNIP1 HTATSF1 HTATSF1 MTHFSD MTHFSD LSM7 LSM7 ENSMFAP00000026069 ENSMFAP00000026069 USP49 USP49 ENSMFAP00000025380 ENSMFAP00000025380 ENSMFAP00000025379 ENSMFAP00000025379 DDX39A DDX39A CWC15 CWC15 GCFC2 GCFC2 BCAS2 BCAS2 TXNL4B TXNL4B NOL3 NOL3 EIF4A3 EIF4A3 ENSMFAP00000024414 ENSMFAP00000024414 ENSMFAP00000024185 ENSMFAP00000024185 NOVA2 NOVA2 DBR1 DBR1 USP4 USP4 TFIP11 TFIP11 METTL3 METTL3 GPATCH11 GPATCH11 TRA2A TRA2A CLNS1A CLNS1A SF3A3 SF3A3 BUD13 BUD13 SRPK3 SRPK3 WBP11 WBP11 ENSMFAP00000021905 ENSMFAP00000021905 LSM8 LSM8 PRPF40B PRPF40B ENSMFAP00000021521 ENSMFAP00000021521 BUD31 BUD31 RBM17 RBM17 SNRPF SNRPF SF1 SF1 RALY RALY LSM6 LSM6 ENSMFAP00000019800 ENSMFAP00000019800 WDR25 WDR25 RBM10 RBM10 U2AF1 U2AF1 DNAJC17 DNAJC17 MAGOH MAGOH DHX38 DHX38 SNRPD2-4 SNRPD2-4 GEMIN5 GEMIN5 YTHDC1 YTHDC1 SF3A1 SF3A1 LENG8 LENG8 DDX41 DDX41 ENSMFAP00000017562 ENSMFAP00000017562 LUC7L3 LUC7L3 SNRPC SNRPC DDX20 DDX20 ENSMFAP00000017194 ENSMFAP00000017194 SMN1-2 SMN1-2 MTREX MTREX RBM5 RBM5 ENSMFAP00000016862 ENSMFAP00000016862 SNRPB2 SNRPB2 ENSMFAP00000016174 ENSMFAP00000016174 CWF19L1 CWF19L1 ENSMFAP00000016083 ENSMFAP00000016083 LSM4 LSM4 ENSMFAP00000015969 ENSMFAP00000015969 FRG1 FRG1 ENSMFAP00000015825 ENSMFAP00000015825 SNU13 SNU13 NCBP1 NCBP1 AQR AQR ENSMFAP00000014996 ENSMFAP00000014996 SNRPC-2 SNRPC-2 ENSMFAP00000014588 ENSMFAP00000014588 GEMIN7 GEMIN7 LSM5-2 LSM5-2 WDR77 WDR77 TGS1 TGS1 PQBP1 PQBP1 XAB2 XAB2 SF3B5 SF3B5 ENSMFAP00000013734 ENSMFAP00000013734 DDX5 DDX5 SRSF8 SRSF8 ENSMFAP00000013256 ENSMFAP00000013256 ENSMFAP00000013227 ENSMFAP00000013227 SNRPG-2 SNRPG-2 ENSMFAP00000012431 ENSMFAP00000012431 CELF5 CELF5 PRPF4B PRPF4B SNRPA1 SNRPA1 SNRPD2-3 SNRPD2-3 ENSMFAP00000011824 ENSMFAP00000011824 DCPS DCPS RNF113A RNF113A RBMXL3 RBMXL3 GEMIN2 GEMIN2 WDR83 WDR83 ENSMFAP00000011196 ENSMFAP00000011196 ENSMFAP00000011123 ENSMFAP00000011123 LSM8-2 LSM8-2 PTBP2 PTBP2 ENSMFAP00000010843 ENSMFAP00000010843 SNRPD2-2 SNRPD2-2 SNRNP35 SNRNP35 SMN1 SMN1 ENSMFAP00000010556 ENSMFAP00000010556 PRPF38B PRPF38B RSRC1 RSRC1 ZCRB1-2 ZCRB1-2 ENSMFAP00000009758 ENSMFAP00000009758 PRPF39 PRPF39 HNRNPA3 HNRNPA3 CDC5L CDC5L SFPQ SFPQ STRAP STRAP LSM2 LSM2 ENSMFAP00000008862 ENSMFAP00000008862 NCBP2 NCBP2 UBL5 UBL5 PRPF31 PRPF31 ENSMFAP00000008638 ENSMFAP00000008638 PRMT5 PRMT5 ALYREF ALYREF ENSMFAP00000008116 ENSMFAP00000008116 TXNL4A TXNL4A RBMX2 RBMX2 GEMIN6 GEMIN6 ZMAT2 ZMAT2 NOVA1 NOVA1 RBM6 RBM6 ENSMFAP00000006611 ENSMFAP00000006611 ENSMFAP00000006286 ENSMFAP00000006286 SFSWAP SFSWAP HNRNPC HNRNPC CELF6 CELF6 SF3A2 SF3A2 HNRNPA2B1 HNRNPA2B1 SART1 SART1 ENSMFAP00000005583 ENSMFAP00000005583 RBM44 RBM44 SRSF5 SRSF5 CDC40 CDC40 CWC25 CWC25 ENSMFAP00000004942 ENSMFAP00000004942 PPIE PPIE RNPC3 RNPC3 SLU7 SLU7 SRSF7 SRSF7 PLRG1 PLRG1 MAGOHB MAGOHB ENSMFAP00000004173 ENSMFAP00000004173 SNRPD3 SNRPD3 SRSF12 SRSF12 SYNCRIP SYNCRIP PRPF6 PRPF6 SNRPD2 SNRPD2 ENSMFAP00000002089 ENSMFAP00000002089 HNRNPU HNRNPU ENSMFAP00000001883 ENSMFAP00000001883 SNW1 SNW1 GEMIN8 GEMIN8 DNAJC8 DNAJC8 GPKOW GPKOW KDM1A KDM1A IK IK CDK13 CDK13 CWC22 CWC22 PRMT7 PRMT7 ENSMFAP00000045669 ENSMFAP00000045669 ENSMFAP00000045632 ENSMFAP00000045632 HNRNPM HNRNPM CACTIN CACTIN ENSMFAP00000045276 ENSMFAP00000045276 ENSMFAP00000044874 ENSMFAP00000044874 HNRNPH3 HNRNPH3 ENSMFAP00000044359 ENSMFAP00000044359 SNRNP200 SNRNP200 PRPF38A PRPF38A PRPF4 PRPF4 SRSF9 SRSF9 GEMIN4 GEMIN4 CTNNBL1 CTNNBL1 ZRSR2 ZRSR2 SRSF3 SRSF3 U2AF2 U2AF2 CELF3 CELF3 PRPF8 PRPF8 ENSMFAP00000042686 ENSMFAP00000042686 ENSMFAP00000042675 ENSMFAP00000042675 SRSF1 SRSF1 SNRPE SNRPE CRNKL1 CRNKL1 SART3 SART3 PRPF3 PRPF3 HNRNPR HNRNPR SNRNP70 SNRNP70 SCNM1 SCNM1 ZCRB1 ZCRB1 SETX SETX MFAP1 MFAP1 CASC3 CASC3 RBM41 RBM41 DHX9 DHX9 ENSMFAP00000041006 ENSMFAP00000041006 ENSMFAP00000040857 ENSMFAP00000040857 FMC1-LUC7L2 FMC1-LUC7L2 USP39 USP39 SNRPG SNRPG ENSMFAP00000040515 ENSMFAP00000040515 PPIL1 PPIL1 ENSMFAP00000040063 ENSMFAP00000040063 ENSMFAP00000040050 ENSMFAP00000040050 RBM19 RBM19 DDX17 DDX17 SRSF10 SRSF10 ENSMFAP00000039639 ENSMFAP00000039639 CWF19L2 CWF19L2 SNRPB SNRPB PPIL3 PPIL3 CD2BP2 CD2BP2 PRPF40A PRPF40A CCDC130 CCDC130 LSM5 LSM5 RBMXL2 RBMXL2 U2AF1L4 U2AF1L4 ENSMFAP00000036332 ENSMFAP00000036332 GPATCH1 GPATCH1 PPIH PPIH ENSMFAP00000035908 ENSMFAP00000035908 WBP4 WBP4 DDX39B DDX39B ENSMFAP00000035649 ENSMFAP00000035649 RBM42 RBM42 SNRNP27 SNRNP27 RBM22 RBM22 ENSMFAP00000034721 ENSMFAP00000034721 LUC7L LUC7L ENSMFAP00000034267 ENSMFAP00000034267 DHX16 DHX16 CELF1 CELF1 SRRM2 SRRM2 ENSMFAP00000033862 ENSMFAP00000033862 ENSMFAP00000033787 ENSMFAP00000033787 SF3B2 SF3B2 ENSMFAP00000033576 ENSMFAP00000033576 C19orf54 C19orf54 KHDC4 KHDC4 LSM3 LSM3 PHF5A PHF5A ENSMFAP00000033042 ENSMFAP00000033042 ENSMFAP00000032734 ENSMFAP00000032734 PAXBP1 PAXBP1 ESRP2 ESRP2 ENSMFAP00000032241 ENSMFAP00000032241 ENSMFAP00000032199 ENSMFAP00000032199 ISY1 ISY1 SRSF6 SRSF6 PRPF19 PRPF19 ENSMFAP00000031236 ENSMFAP00000031236 SCAF11 SCAF11 SF3B1 SF3B1 SF3B6 SF3B6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
SNRNP25Small nuclear ribonucleoprotein U11/U12 subunit 25. (134 aa)
ENSMFAP00000030958Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (159 aa)
ENSMFAP00000030936Uncharacterized protein. (60 aa)
TRA2BRRM domain-containing protein. (288 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
ESS2Ess-2 splicing factor homolog. (476 aa)
ENSMFAP00000030668Uncharacterized protein. (305 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events; Belongs to the snRNP SmB/SmN family. (244 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
C9orf78Chromosome 9 open reading frame 78. (289 aa)
SYF2SYF2 pre-mRNA splicing factor. (243 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
C11orf58Chromosome 11 open reading frame 58. (183 aa)
PSIP1PC4 and SFRS1 interacting protein 1. (530 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (472 aa)
SRPK2Protein kinase domain-containing protein. (702 aa)
PRR3Proline rich 3. (188 aa)
SRSF2Testis cDNA, clone: QtsA-15801, similar to human splicing factor, arginine/serine-rich 2 (SFRS2). (221 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
ENSMFAP00000026895RRM domain-containing protein. (350 aa)
DHX8DEAH-box helicase 8. (1222 aa)
SNIP1Smad nuclear interacting protein 1. (396 aa)
HTATSF1HIV-1 Tat specific factor 1. (754 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (424 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
ENSMFAP00000026069SEC63 domain-containing protein. (319 aa)
USP49Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (688 aa)
ENSMFAP00000025380Uncharacterized protein. (155 aa)
ENSMFAP00000025379J domain-containing protein. (181 aa)
DDX39ADExD-box helicase 39A. (435 aa)
CWC15CWC15 spliceosome associated protein homolog. (229 aa)
GCFC2GC-rich sequence DNA-binding factor 2. (790 aa)
BCAS2BCAS2, pre-mRNA processing factor. (225 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
NOL3CARD domain-containing protein. (258 aa)
EIF4A3Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] (412 aa)
ENSMFAP00000024414Uncharacterized protein. (275 aa)
ENSMFAP00000024185Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)
NOVA2NOVA alternative splicing regulator 2. (455 aa)
DBR1DBR1 domain-containing protein. (544 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (948 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
GPATCH11G-patch domain containing 11. (263 aa)
TRA2ATransformer 2 alpha homolog. (282 aa)
CLNS1AChloride nucleotide-sensitive channel 1A. (237 aa)
SF3A3Matrin-type domain-containing protein. (504 aa)
BUD13BUD13 homolog. (619 aa)
SRPK3SRSF protein kinase 3. (625 aa)
WBP11WW domain binding protein 11. (641 aa)
ENSMFAP00000021905Uncharacterized protein. (195 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (892 aa)
ENSMFAP00000021521Uncharacterized protein. (154 aa)
BUD31BUD31 homolog. (144 aa)
RBM17RNA binding motif protein 17. (401 aa)
SNRPFSm domain-containing protein. (127 aa)
SF1Splicing factor 1. (655 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (309 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
ENSMFAP00000019800Uncharacterized protein. (274 aa)
WDR25WD repeat domain 25. (544 aa)
RBM10RNA binding motif protein 10. (995 aa)
U2AF1Uncharacterized protein. (246 aa)
DNAJC17DnaJ heat shock protein family (Hsp40) member C17. (304 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
DHX38DEAH-box helicase 38. (1234 aa)
SNRPD2-4Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (85 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1512 aa)
YTHDC1YTH domain containing 1. (736 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
LENG8Leukocyte receptor cluster member 8. (873 aa)
DDX41DEAD-box helicase 41. (622 aa)
ENSMFAP00000017562J domain-containing protein. (228 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (489 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (173 aa)
DDX20DEAD-box helicase 20. (856 aa)
ENSMFAP00000017194J domain-containing protein. (243 aa)
SMN1-2Tudor domain-containing protein. (320 aa)
MTREXMtr4 exosome RNA helicase. (1051 aa)
RBM5RNA binding motif protein 5. (815 aa)
ENSMFAP00000016862Uncharacterized protein. (372 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
ENSMFAP00000016174Uncharacterized protein. (365 aa)
CWF19L1Uncharacterized protein. (537 aa)
ENSMFAP00000016083RRM domain-containing protein. (250 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
ENSMFAP00000015969Sm domain-containing protein. (59 aa)
FRG1FSHD region gene 1. (258 aa)
ENSMFAP00000015825Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SNU13NHP2-like protein 1, N-terminally processed; Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. (158 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1480 aa)
ENSMFAP00000014996Uncharacterized protein. (308 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
ENSMFAP00000014588Uncharacterized protein. (146 aa)
GEMIN7Gem nuclear organelle associated protein 7. (131 aa)
LSM5-2U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
WDR77WD repeat domain 77. (342 aa)
TGS1Trimethylguanosine synthase 1. (854 aa)
PQBP1Polyglutamine binding protein 1. (265 aa)
XAB2XPA binding protein 2. (855 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
ENSMFAP00000013734Uncharacterized protein. (133 aa)
DDX5Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] (614 aa)
SRSF8Serine and arginine rich splicing factor 8. (287 aa)
ENSMFAP00000013256Uncharacterized protein. (319 aa)
ENSMFAP00000013227Cir_N domain-containing protein. (64 aa)
SNRPG-2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
ENSMFAP00000012431RRM domain-containing protein. (296 aa)
CELF5Uncharacterized protein. (398 aa)
PRPF4BPre-mRNA processing factor 4B. (1007 aa)
SNRPA1U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. (255 aa)
SNRPD2-3Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
ENSMFAP00000011824Uncharacterized protein; Belongs to the DEAD box helicase family. (387 aa)
DCPSDecapping enzyme, scavenger. (339 aa)
RNF113ARing finger protein 113A. (344 aa)
RBMXL3RRM domain-containing protein. (671 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (279 aa)
WDR83WD repeat domain 83. (315 aa)
ENSMFAP00000011196Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
ENSMFAP00000011123Protein kinase domain-containing protein. (160 aa)
LSM8-2U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PTBP2Polypyrimidine tract binding protein 2. (537 aa)
ENSMFAP00000010843J domain-containing protein. (347 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (247 aa)
SMN1Survival motor neuron protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the ch [...] (294 aa)
ENSMFAP00000010556Uncharacterized protein. (167 aa)
PRPF38BPre-mRNA processing factor 38B. (546 aa)
RSRC1Arginine and serine rich coiled-coil 1. (334 aa)
ZCRB1-2Uncharacterized protein. (217 aa)
ENSMFAP00000009758Uncharacterized protein. (512 aa)
PRPF39Pre-mRNA processing factor 39. (548 aa)
HNRNPA3Heterogeneous nuclear ribonucleoprotein A3. (378 aa)
CDC5LCell division cycle 5 like. (802 aa)
SFPQSplicing factor proline and glutamine rich. (707 aa)
STRAPWD_REPEATS_REGION domain-containing protein. (363 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
ENSMFAP00000008862Uncharacterized protein. (77 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
UBL5Testis cDNA, clone: QtsA-15893, similar to human ubiquitin-like 5 (UBL5). (73 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
ENSMFAP00000008638Sm domain-containing protein. (65 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties (By similarity). Mono- and dimethylates arginine resi [...] (620 aa)
ALYREFAly/REF export factor. (257 aa)
ENSMFAP00000008116Uncharacterized protein. (352 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
RBMX2RNA binding motif protein X-linked 2. (322 aa)
GEMIN6Gem nuclear organelle associated protein 6. (166 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
NOVA1RNA-binding protein Nova-1; May regulate RNA splicing or metabolism in a specific subset of developing neurons. (507 aa)
RBM6G-patch domain-containing protein. (120 aa)
ENSMFAP00000006611Uncharacterized protein. (232 aa)
ENSMFAP00000006286Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (81 aa)
SFSWAPSplicing factor SWAP. (1094 aa)
HNRNPCRRM domain-containing protein. (321 aa)
CELF6Uncharacterized protein. (481 aa)
SF3A2Splicing factor 3a subunit 2. (464 aa)
HNRNPA2B1Uncharacterized protein. (353 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
ENSMFAP00000005583Uncharacterized protein. (107 aa)
RBM44RNA binding motif protein 44. (1049 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
CDC40Cell division cycle 40. (579 aa)
CWC25CWC25 spliceosome associated protein homolog. (361 aa)
ENSMFAP00000004942Uncharacterized protein. (124 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
RNPC3RNA binding region (RNP1, RRM) containing 3. (518 aa)
SLU7Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. (586 aa)
SRSF7Uncharacterized protein. (235 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
MAGOHBUncharacterized protein. (148 aa)
ENSMFAP00000004173Sm domain-containing protein. (57 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SRSF12Serine and arginine rich splicing factor 12. (261 aa)
SYNCRIPUncharacterized protein. (562 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
ENSMFAP00000002089Uncharacterized protein. (150 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
ENSMFAP00000001883Uncharacterized protein. (137 aa)
SNW1SNW domain containing 1. (571 aa)
GEMIN8Gem nuclear organelle associated protein 8. (242 aa)
DNAJC8J domain-containing protein. (253 aa)
GPKOWG-patch domain and KOW motifs. (476 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
IKIK cytokine, down-regulator of HLA II. (557 aa)
CDK13Cyclin dependent kinase 13. (1511 aa)
CWC22CWC22 spliceosome associated protein homolog. (900 aa)
PRMT7Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (701 aa)
ENSMFAP00000045669SKIP_SNW domain-containing protein. (467 aa)
ENSMFAP00000045632DUF1716 domain-containing protein. (469 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (730 aa)
CACTINCactin, spliceosome C complex subunit. (760 aa)
ENSMFAP00000045276RRM domain-containing protein. (281 aa)
ENSMFAP00000044874Uncharacterized protein. (138 aa)
HNRNPH3Heterogeneous nuclear ribonucleoprotein H3. (346 aa)
ENSMFAP00000044359RRM domain-containing protein. (119 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
PRPF38APre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. (312 aa)
PRPF4Pre-mRNA processing factor 4. (543 aa)
SRSF9Serine and arginine rich splicing factor 9. (187 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1058 aa)
CTNNBL1DUF1716 domain-containing protein. (563 aa)
ZRSR2Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (480 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa)
CELF3CUGBP Elav-like family member 3. (470 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
ENSMFAP00000042686RRM domain-containing protein. (260 aa)
ENSMFAP00000042675Uncharacterized protein. (547 aa)
SRSF1Uncharacterized protein. (253 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (850 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa)
PRPF3Pre-mRNA processing factor 3. (683 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R. (636 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (437 aa)
SCNM1Sodium channel modifier 1. (195 aa)
ZCRB1Uncharacterized protein. (189 aa)
SETXSenataxin. (2680 aa)
MFAP1Testis cDNA, clone: QtsA-15815, similar to human microfibrillar-associated protein 1 (MFAP1). (439 aa)
CASC3CASC3 exon junction complex subunit. (706 aa)
RBM41RNA binding motif protein 41. (409 aa)
DHX9DExH-box helicase 9. (1275 aa)
ENSMFAP00000041006Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa)
ENSMFAP00000040857Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (53 aa)
FMC1-LUC7L2FMC1-LUC7L2 readthrough. (448 aa)
USP39Ubiquitin specific peptidase 39. (565 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
ENSMFAP00000040515Uncharacterized protein. (168 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
ENSMFAP00000040063Uncharacterized protein. (51 aa)
ENSMFAP00000040050Uncharacterized protein. (287 aa)
RBM19RNA binding motif protein 19. (998 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa)
SRSF10RRM domain-containing protein. (262 aa)
ENSMFAP00000039639Uncharacterized protein. (187 aa)
CWF19L2CWF19 like cell cycle control factor 2. (893 aa)
SNRPBSmall nuclear ribonucleoprotein polypeptides B and B1. (330 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
CD2BP2GYF domain-containing protein. (341 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (930 aa)
CCDC130Coiled-coil domain containing 130. (397 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
RBMXL2RNA-binding motif protein, X-linked-like-2. (392 aa)
U2AF1L4Uncharacterized protein. (220 aa)
ENSMFAP00000036332Uncharacterized protein. (363 aa)
GPATCH1G-patch domain containing 1. (883 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
ENSMFAP00000035908J domain-containing protein. (250 aa)
WBP4WW domain binding protein 4. (375 aa)
DDX39BATP-dependent RNA helicase UAP56/SUB2. (428 aa)
ENSMFAP00000035649Uncharacterized protein. (298 aa)
RBM42RNA binding motif protein 42. (480 aa)
SNRNP27SNRNP27 domain-containing protein. (158 aa)
RBM22Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family. (420 aa)
ENSMFAP00000034721Uncharacterized protein. (125 aa)
LUC7LLUC7 like. (371 aa)
ENSMFAP00000034267C3H1-type domain-containing protein. (118 aa)
DHX16DEAH-box helicase 16. (1044 aa)
CELF1CUGBP Elav-like family member 1. (487 aa)
SRRM2Serine/arginine repetitive matrix 2. (2752 aa)
ENSMFAP00000033862Uncharacterized protein. (92 aa)
ENSMFAP00000033787Uncharacterized protein. (251 aa)
SF3B2Splicing factor 3b subunit 2. (896 aa)
ENSMFAP00000033576Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (248 aa)
C19orf54Chromosome 19 open reading frame 54. (351 aa)
KHDC4KH domain containing 4, pre-mRNA splicing factor. (614 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
PHF5APHD finger protein 5A. (110 aa)
ENSMFAP00000033042Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
ENSMFAP00000032734RRM domain-containing protein. (434 aa)
PAXBP1PAX3 and PAX7 binding protein 1. (917 aa)
ESRP2Epithelial splicing regulatory protein 2. (715 aa)
ENSMFAP00000032241Uncharacterized protein. (189 aa)
ENSMFAP00000032199Uncharacterized protein. (314 aa)
ISY1Uncharacterized protein. (285 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
ENSMFAP00000031236Uncharacterized protein. (424 aa)
SCAF11SR-related CTD associated factor 11. (1464 aa)
SF3B1Uncharacterized protein. (74 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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